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Full-Text Articles in Life Sciences
Investigating The Effects Of Cancer Mutations On The Activity Of P300, Meghan Hall
Investigating The Effects Of Cancer Mutations On The Activity Of P300, Meghan Hall
Spring Showcase for Research and Creative Inquiry
Investigating the effects of cancer mutations on the activity of p300
The Use Hela Derived Telomerase On Nk Cells In The Treatment Of Ovarian Cancer, Juwairyah Gunter
The Use Hela Derived Telomerase On Nk Cells In The Treatment Of Ovarian Cancer, Juwairyah Gunter
Spring Showcase for Research and Creative Inquiry
A research proposal for a novel immunotherapy for treating ovarian cancer.
Ability Of Flavonoids To Mimic The Estrogen Receptor To Drive Myeloid Derived Suppressor Cell Differentiation, Megan Bland, Cecilie Elliott, Kathryn Kosiorek
Ability Of Flavonoids To Mimic The Estrogen Receptor To Drive Myeloid Derived Suppressor Cell Differentiation, Megan Bland, Cecilie Elliott, Kathryn Kosiorek
Spring Showcase for Research and Creative Inquiry
Flavonoids are natural compounds found in dietary elements such as soy, grains, and vegetables that have the potential to bind to the estrogen receptor. Activation of the estrogen receptor drives myeloid derived suppressor cell (MDSC) accumulation, cells that increase during cancer, inflammation, and infection. In this study, we are investigating specific flavonoids, such as epigallocatechin-3-gallate (EGCG), kaempferol, naringenin, daidzein, and genistein, for their ability to mimic estrogen. After examination, we expect that MDSC differentiation will decrease upon treatment of the chosen flavonoids, leading to reduced carcinogenic effects.