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Full-Text Articles in Life Sciences
Synaptic Modification Of Inhibitory Inputs To Gaba Neurons In The Ventral Tegmental Area: A Novel Potential Target Mediating Reward And Addiction In The Brain, Jeff Edwards
Journal of Undergraduate Research
The objectives of this award were met, especially in regard to the mentoring focus of the award. The students have been mentored and trained in an effective manner as outlined in my Mentoring Plan (abbreviated below). This includes mentoring students in research, writing, publishing, presenting at conferences, etc. Indeed, one measure of the success of mentoring is demonstrated by the fact that all the students graduating from my lab during this time were accepted to the professional school of their choice (see students listed below). Research, especially where the students are actually involved in all aspects of it including data …
The Role Of Bdnf Expression In Chronic Ethanol Usage, Caleb Porter, Scott Steffensen
The Role Of Bdnf Expression In Chronic Ethanol Usage, Caleb Porter, Scott Steffensen
Journal of Undergraduate Research
It has been observed that chronic exposure to drugs of abuse, particularly opiates, increases brain-derived neurotrophic factor (BDNF) levels in ventral tegmental area (VTA) neurons. In particular, BDNF expression is dramatically increased during drug withdrawal, which would suggest a direct connection between the aversive state of withdrawal and BDNFinduced neuronal plasticity. The purpose of this project was to evaluate the relationship between brain-derived neurotrophic factor (BDNF) expression, which is dramatically increased within the ventral tegmental area (VTA) during drug abuse, and alcohol withdrawal symptoms.