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Full-Text Articles in Life Sciences
Health Care Delivery System: Current Trends And Prospects For The Future, Vinod K. Sahney, Douglas S. Peters, Stanley R. Nelson
Health Care Delivery System: Current Trends And Prospects For The Future, Vinod K. Sahney, Douglas S. Peters, Stanley R. Nelson
Henry Ford Hospital Medical Journal
No abstract provided.
Issues Facing Group Practice In The 1990s, Bruce W. Steinhauer
Issues Facing Group Practice In The 1990s, Bruce W. Steinhauer
Henry Ford Hospital Medical Journal
No abstract provided.
The Ambulatory Care "Gold Rush?", Michael A. Slubowski
The Ambulatory Care "Gold Rush?", Michael A. Slubowski
Henry Ford Hospital Medical Journal
No abstract provided.
The Employer-Purchaser Impact On Health Care Delivery And Financing, Robert Asmussen
The Employer-Purchaser Impact On Health Care Delivery And Financing, Robert Asmussen
Henry Ford Hospital Medical Journal
No abstract provided.
Marketing Physician Practices: Developing An Action Plan For Success, Barbara Steiner, Douglas Klegon, William Conway, Patricia Mccarthy
Marketing Physician Practices: Developing An Action Plan For Success, Barbara Steiner, Douglas Klegon, William Conway, Patricia Mccarthy
Henry Ford Hospital Medical Journal
No abstract provided.
Use Of A "Permission Giving" Patient Checklist In Identification Of Social And Sexual Problems, William B. Anderson
Use Of A "Permission Giving" Patient Checklist In Identification Of Social And Sexual Problems, William B. Anderson
Henry Ford Hospital Medical Journal
A checklist derived from the ACOG bulletin entitled "Communication of Sexual Problems in Office Gynecology" was given to 614 women. The findings demonstrate that social and sexual concerns are encountered frequently in the practice of clinical gynecology and that a checklist is effective in identifying these concerns.
No Miracle Remedies In Sight For Financing Health Care For The Poor, John M. Kuder
No Miracle Remedies In Sight For Financing Health Care For The Poor, John M. Kuder
Henry Ford Hospital Medical Journal
No abstract provided.
Money And Manpower In Graduate Medical Education, David C. Leach
Money And Manpower In Graduate Medical Education, David C. Leach
Henry Ford Hospital Medical Journal
No abstract provided.
Alternative Delivery Systems: The Changing Role Of The Physician, David Siegel, Douglas Klegon
Alternative Delivery Systems: The Changing Role Of The Physician, David Siegel, Douglas Klegon
Henry Ford Hospital Medical Journal
No abstract provided.
Clinical And Laboratory Study Of Sickle Cell/Β-Thalassemia, Koichi Maeda, Ellis J. Van Slyck, Robert C. Hawley
Clinical And Laboratory Study Of Sickle Cell/Β-Thalassemia, Koichi Maeda, Ellis J. Van Slyck, Robert C. Hawley
Henry Ford Hospital Medical Journal
We have studied 39 patients doubly heterozygous for sickle cell/β-thalassemia, 12 with sickle cell/βo- thalassemia and 27 with sickle cell/β+-thalassemia. Generally, sickle cell/βo-thalassemia is considered more severe than sickle cell/β+-thalassemia. In our study, however clinical complications in the group with sickle cell/β+-thalassemia were seen almost as frequently as in the group with sickle cell/βo-thalassemia. A wide variety of clinical manifestations were seen in both groups of patients.
Radiographic Features Of Anterior Cruciate Ligament Reconstruction, Mark I. Burnstein, Burton I. Ellis, Robert A. Teitge, Martin L. Gross, Christopher K. Shier
Radiographic Features Of Anterior Cruciate Ligament Reconstruction, Mark I. Burnstein, Burton I. Ellis, Robert A. Teitge, Martin L. Gross, Christopher K. Shier
Henry Ford Hospital Medical Journal
Anterior cruciate ligament disruption is a common injury that occurs in contact sports such as football. The treating orthopedic surgeon may elect any of a variety of therapeutic options. Surgical management may consist of primary repair of the torn ligament or replacement of the torn ligament with graft material, known as anterior cruciate ligament reconstruction (ACER). Many physicians, including radiologists, are unfamiliar with the surgical procedure or the expected postoperative radiographic appearance of ACER. Assessment of radiographs following ACER, as with many surgical procedures, requires understanding of the surgical procedure. We present our experience in assessing the postoperative radiographs of …
Characteristics, Mortality, And Outcome Of Infants Weighing Over 2500 Grams Who Require Intensive Care, Anthony Udo-Inyang, Chang Y. Lee
Characteristics, Mortality, And Outcome Of Infants Weighing Over 2500 Grams Who Require Intensive Care, Anthony Udo-Inyang, Chang Y. Lee
Henry Ford Hospital Medical Journal
Documentations of morbidity and mortality of infants weighing over 2500 g who require intensive care, along with research to improve their outcome, have not received adequate emphasis in the literature. From 1981 to 1984 these infants accounted for 495 (40.1%) admissions and 16 (9.8%) deaths in Henry Ford Hospital's neonatal intensive care unit. The most common diagnoses were hematologic diseases (24.6%), meconium aspiration (20.4%), respiratory distress/asphyxia (17.2%), congenital anomalies (13.8%), and infants of diabetic mothers (10.7%). Infant mortality was 56.2% from congenital anomalies. 25% from meconium aspiration, 6.2% from infection, 6.2% from maternal accident, and 6.2% from accidental neonatal asphyxia. …
The First-Bite Syndrome, William S. Haubrich
The First-Bite Syndrome, William S. Haubrich
Henry Ford Hospital Medical Journal
Patients presenting with esophageal disorders often describe what can be called a "first-bite syndrome." The condition can be discerned by its characteristic clinical features. It may be a variant of diffuse esophageal spasm. While in a majority of patients it is a benign functional disturbance, it can be a harbinger of carcinoma. When of functional origin, it is amenable, in most cases, to relatively simple medical management.
Small Cell Carcinoma Of The Lung In The Intensive Care Unit, Paul Harkaway, Cynthia Glines, Michael Eichenhorn, Paul Kvale, Robert Chapman, John Popovich Jr.
Small Cell Carcinoma Of The Lung In The Intensive Care Unit, Paul Harkaway, Cynthia Glines, Michael Eichenhorn, Paul Kvale, Robert Chapman, John Popovich Jr.
Henry Ford Hospital Medical Journal
The outcome of 29 patients with a diagnosis of small cell carcinoma of the lung admitted to the medical intensive care unit (MICU) from 1980 through 1984 was reviewed retrospectively. Respiratory failure was the most common admitting diagnosis (23 patients [80%]). followed by cardiopulmonary arrest (three patients [10%]), and hypotension (three patients [10%] ). Only five patients survived to leave the MICU, and only two of these patients lived longer than two months after MICU discharge. Of the features examined, the absence of sepsis was the only statistically significant predictor of MICU survival. Treatment of the malignancy did not appear …
Robert K. Nixon, Md, Robert J. Priest
Robert K. Nixon, Md, Robert J. Priest
Henry Ford Hospital Medical Journal
No abstract provided.
Echocardiographic Features Of Metastatic Pericardial And Myocardial Malignancy, Carey Green, Mohsin Alam, Howard S. Rosman, Jeffrey B. Lakier
Echocardiographic Features Of Metastatic Pericardial And Myocardial Malignancy, Carey Green, Mohsin Alam, Howard S. Rosman, Jeffrey B. Lakier
Henry Ford Hospital Medical Journal
Clinical and echocardiographic features of a patient with extensive metastasis to the pericardium and myocardium are presented. Echocardiography revealed pericardial effusion, markedly thickened pericardium, and myocardium with increased echogenicity. These findings were subsequently confirmed during surgery and autopsy, which revealed marked tumor encasement of the heart and pericardial myocardial infiltration.
Heart Failure: New Questions And Insights About An Old Foe, Jeffrey B. Lakier
Heart Failure: New Questions And Insights About An Old Foe, Jeffrey B. Lakier
Henry Ford Hospital Medical Journal
No abstract provided.
Pathophysiology Of Heart Failure, Mihai Gheorghiade, Jeffrey B. Lakier
Pathophysiology Of Heart Failure, Mihai Gheorghiade, Jeffrey B. Lakier
Henry Ford Hospital Medical Journal
Heart failure occurs when the heart is unable to maintain a cardiac output sufficient to satisfy the oxygen requirements of the body despite adequate blood volume and hemoglobin content. Regardless of the initial cause of heart failure and in spite of compensatory mechanisms, patients often follow a course of worsening heart failure that is characterized by a low cardiac output, high filling pressures, and increased peripheral vascular resistance. In addition to persistence of the initiating event, cardiac deterioration may be caused or aggravated by a variety of factors including depletion of cardiac norepinephrine stores, down-regulation of myocardial beta-adrenergic receptors, microvascular …
"Congestion": An Infrequent Feature In Patients With Chronic Heart Failure On Therapy, Syed M. Jafri, Jeffrey B. Lakier, Howard S. Rosman, Sidney Goldstein
"Congestion": An Infrequent Feature In Patients With Chronic Heart Failure On Therapy, Syed M. Jafri, Jeffrey B. Lakier, Howard S. Rosman, Sidney Goldstein
Henry Ford Hospital Medical Journal
The clinical presentation of chronic heart failure has changed with advances in therapy, and the physical findings of congestion are now inconsistently present. To determine the clinical signs of congestion, we studied the clinical findings of 44 patients who had chronic heart failure and abnormal left ventricular ejection fractions (23 ± 10%). Signs of pulmonary edema manifested as rales were absent in all patients in New York Heart Association (NYHA) classes I and II, in 66% of patients in NYHA class III, and in 14% of patients in NYHA class IV. Signs of right heart failure manifested as elevated jugular …
Echocardiographic Evaluation Of Patients With Congestive Heart Failure, Mohsin Alam
Echocardiographic Evaluation Of Patients With Congestive Heart Failure, Mohsin Alam
Henry Ford Hospital Medical Journal
Echocardiography is a useful noninvasive test for evaluating patients with suspected heart failure and enlarged cardiac silhouette. This test can obtain the dimensions and wall thickness of all four cardiac chambers and can evaluate left ventricular function. The test results are reproducible, and in many instances the etiology of heart failure can be determined.
Altered Platelet Function In Patients With Severe Congestive Heart Failure, Syed M. Jafri, Jeanne M. Riddle, Sundara B. K. Raman, Sidney Goldstein
Altered Platelet Function In Patients With Severe Congestive Heart Failure, Syed M. Jafri, Jeanne M. Riddle, Sundara B. K. Raman, Sidney Goldstein
Henry Ford Hospital Medical Journal
Platelet function was assessed in 15 patients with severe congestive heart failure (CHF) and in 26 control subjects of similar ages. The platelet count (mm3), surface reactivity, aggregometry studies, release factors, and circulating aggregates were investigated. The mean number of circulating platelets was normal, but a hyperactive platelet response was found in 53% of the CHF patients. CHF patients had a 42% mean for the spread type platelet, and the average number of aggregates was 64: control subjects had a 12% mean for the spread type platelet, and the average number of aggregates was 40 (p < 0.05). Aggregation with all of the inducers was normal, although 27% of CHF patients showed spontaneous aggregation. The mean plasma levels of both platelet factor 4 and betathromboglobulin were abnormally elevated. No circulating platelet aggregates were detected. Our studies indicate that platelet function is abnormal in patients with CHF. The abnormal platelet reactivity found might contribute to the increased incidence of thromboembolic events observed in CHF patients.
Restrictive Cardiomyopathy, Remigio Garcia, Mohsin Alam
Restrictive Cardiomyopathy, Remigio Garcia, Mohsin Alam
Henry Ford Hospital Medical Journal
Restrictive obliterative cardiomyopathy, with emphasis on amyloid infiltration of the heart, is discussed. The presence of right-sided failure associated with low-voltage electrocardiographic complexes may simulate constrictive pericarditis. Intractable congestive heart failure is the most frequent presentation of amyloid heart disease, and the average survival from diagnosis is 14 months. Digitalis sensitivity and fatal arrhythmias are notoriously common. Other important, although less common, restrictive cardiomyopathies include 1) hemochromatosis, which is the only reversible cause of heart failure in this group: and 2) endomyocardial fibrosis, which is rarely seen in temperate zones but which is amenable to surgical palliation. Many questions regarding …
Potassium And Heart Failure, Howard S. Rosman, Mihai Gheorghiade, Sidney Goldstein
Potassium And Heart Failure, Howard S. Rosman, Mihai Gheorghiade, Sidney Goldstein
Henry Ford Hospital Medical Journal
No abstract provided.
Beta-Adrenergic Blocking Agents In Congestive Heart Failure, Sidney Goldstein
Beta-Adrenergic Blocking Agents In Congestive Heart Failure, Sidney Goldstein
Henry Ford Hospital Medical Journal
Although recent physiologic studies suggest that increased catecholamine release in humans may in the long run represent an adverse homeostatic mechanism, this catecholamine release is acutely important in permitting human response to stress. Clinical interventions with beta-adrenergic blocking agents have showed a salutary effect on cardiac function in patients with severe heart failure: in patients with heart failure associated with myocardial infarction, these agents may help improve mortality rates. These studies indicate that the drugs are well tolerated when used carefully in these high-risk patients.
The Effect Of Aortic Valve Replacement On Left Ventricular Function In Patients With Aortic Valvular Disease, Tennyson Lee, Cathy L. Glick, Jeffrey B. Lakier, Sidney Goldstein
The Effect Of Aortic Valve Replacement On Left Ventricular Function In Patients With Aortic Valvular Disease, Tennyson Lee, Cathy L. Glick, Jeffrey B. Lakier, Sidney Goldstein
Henry Ford Hospital Medical Journal
Despite improved surgical techniques and survival in patients following aortic valve replacement for aortic stenosis and aortic insufficiency, the proper timing for surgery remains controversial. The incomplete reversibility of left ventricular dysfunction remains a concern, and postoperative improvement of left ventricular function is not consistently demonstrated. We studied 11 patients with aortic stenosis and nine patients with aortic insufficiency using angiographic and radioisotope assessment of left ventricular function preoperatively. Postoperative left ventricular function was assessed over nine to 13 months by radioisotope multiple-gated acquisition (MUGA) scan. All patients with impaired left ventricular function preoperatively showed slow but significant recovery toward …
New Positive Inotropic Agents, Syed M. Jafri, James A. Bristol
New Positive Inotropic Agents, Syed M. Jafri, James A. Bristol
Henry Ford Hospital Medical Journal
Current therapy for heart failure remains inadequate. New positive inotropic agents that augment myocardial contractility have been introduced. The positive inotropic effects of these nonglycoside, nonsympathomimetic agents are due, at least in part, to inhibition of cardiac phosphodiesterase activity and hence to an increase in myocardial cyclic AMP levels. These agents also have vasodilator properties through their effects on the enzyme phosphodiesterase in the vascular smooth muscle. Recent developments in the preclinical pharmacology, mechanism of action, and clinical experience with these new inotrope vasodilators are presented in this review. The role these drugs will play in revising our therapeutic strategy …