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Full-Text Articles in Life Sciences
The Effectiveness Of Oxandrolone In Promoting Linear Growth In Growth Hormone Deficient Children, Charles B. Wolf, Raymond C. Mellinger, Lewis B. Morrow, M. Saeed-Uz Zafar
The Effectiveness Of Oxandrolone In Promoting Linear Growth In Growth Hormone Deficient Children, Charles B. Wolf, Raymond C. Mellinger, Lewis B. Morrow, M. Saeed-Uz Zafar
Henry Ford Hospital Medical Journal
This two-year study consisted of a comparison of oxandrolone and growth hormone for the treatment of five children with documented growth hormone deficiency. Previously, androgens have been reported to be relatively ineffective in accelerating linear growth In growth hormone deficient children. Oxandrolone was administered for one year. Growth hormone was added in the second six months and then was given as a single agent in the third six months. Growth accelerated markedly in all patients. Only one child showed more rapid growth with the addition of growth hormone while two children actually grew more rapidly under the Influence of oxandrolone …
Surgical Treatment Of Liver Trauma: Technical Considerations And Case Reports, C. Grodsinsky, T. A. Fox Jr., B. E. Brush
Surgical Treatment Of Liver Trauma: Technical Considerations And Case Reports, C. Grodsinsky, T. A. Fox Jr., B. E. Brush
Henry Ford Hospital Medical Journal
The incidence of abdominal trauma, and thus that of liver trauma, has been increasing in the past few years. Improvements in the understanding of the anatomy of the liver and improvements in diagnostic techniques have resulted in shorter and better operations with less delay between injury and surgery. Improvements in transportation to adequate hospital facilities and vigorous resuscitative measures have also contributed to lowering the mortality rate for this type of injury. Suggestions are made for the surgical management of liver injuries, together with illustrative case reports.
Near Basal Blood Pressure: A Method Applicable To Clinical Practice, John R. Caldwell
Near Basal Blood Pressure: A Method Applicable To Clinical Practice, John R. Caldwell
Henry Ford Hospital Medical Journal
A method is described for determining near basal blood pressure (NBBP) measurements that is applicable to outpatient clinic or office use in daily practice. In our clinic, patients' mean casual pressure was significantly higher than the NBBP, the difference being 40 mm Hg systolic (p < .001) and 18 mm Hg diastolic (p < .001). In hospitalized patients the casual blood pressure was higher than the fourth to sixth day hospital average, and the hospital average was higher than NBBP. The difference between the last two was 15 mm Hg systolic (p <. 005) and 9 mm Hg diastolic (p < .005). In patients recording blood pressure readings at home the average weekly home-recorded blood pressure was not significantly different from NBBP during the same week, -1 mm Hg systolic (p > .80) and 4 mm Hg diastolic (p > .10). NBBP by this method offers a practical way to estimate the average daily blood pressure.
Electrical Alternans In Cardiac Tamponade, Andreas P. Niarchos
Electrical Alternans In Cardiac Tamponade, Andreas P. Niarchos
Henry Ford Hospital Medical Journal
Of nine patients with pericardial effusion due to various causes, four developed cardiac tamponade. Electrical alternans was present In all four, being total in three, and ventricular in one. From the diagnostic point of view, the alternans corresponded with the clinical diagnosis of cardiac tamponade and the radiological signs of a large pericardial effusion. The pericardial fluid was hemorrhagic in three patients and transudate (hydropericardium) in the fourth. In two patients alternans was present with heart rates below 100 per minute. Apart from the exact (1:1) type of electrical alternans, three new types are described; a 2:1, 3:1 and a …
Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research
Henry Ford Hospital Medical Journal
No abstract provided.
Efficacy Of Betaprone With Ultraviolet Irradiation On Hepatitis B Antigen In Human Plasma Pools (A Retrospective Study), Gerald A. Logrippo, Hajime Hayashi
Efficacy Of Betaprone With Ultraviolet Irradiation On Hepatitis B Antigen In Human Plasma Pools (A Retrospective Study), Gerald A. Logrippo, Hajime Hayashi
Henry Ford Hospital Medical Journal
In a retrospective study, hepatitis B antigen (HB Ag) was found in 14 lots of human plasma pools (16-20 liters each) that had been treated by the combined Betaprone (BPL) with ultraviolet (UV) irradiation procedure. No evidence of clinical hepatitis was found during a six-month follow-up after 185.2 liters of HB Ag positive plasma were Infused into 257 patients. Since HB Ag positive blood products treated by BPL with UV produced no clinical hepatitis, it is evident that our treatment is efficacious against hepatitis virus agents.
Blood Pressure In Hypertension, Lawrence H. Warbasse Jr.
Blood Pressure In Hypertension, Lawrence H. Warbasse Jr.
Henry Ford Hospital Medical Journal
No abstract provided.
Localization Of Deep Abscesses With Radioactive Isotopes: An Experimental Study, H. M. Allen, R. Berguer, L. A. Dusault, M. A. Block
Localization Of Deep Abscesses With Radioactive Isotopes: An Experimental Study, H. M. Allen, R. Berguer, L. A. Dusault, M. A. Block
Henry Ford Hospital Medical Journal
Life-endangering effects of deep abscesses make early and precise identification and localization important to permit adequate surgical drainage. An experiment was undertaken to study the feasibility of detecting abscesses by using leucocytes tagged with radioactive isotopes. For the labeling, 51chromium appeared preferable to 131iodine or 99technetium. Leucocytes so labelled will concentrate sufficiently in abscesses to permit identification of abscesses by scintillation scanning. For clinical application, techniques require further simplification and refinement to eliminate interference by collection of radioactive isotopes in the liver and spleen.
A Clinical Trial Of Tobramycin With Pharmacological And Microbiological Studies, Keith Burch, Richard D. Nichols, Edward L. Quinn, Frank Cox, Evelyn J. Fisher, T. Madhavan, Donald Pohlod
A Clinical Trial Of Tobramycin With Pharmacological And Microbiological Studies, Keith Burch, Richard D. Nichols, Edward L. Quinn, Frank Cox, Evelyn J. Fisher, T. Madhavan, Donald Pohlod
Henry Ford Hospital Medical Journal
Tobramycin, a new aminoglycoside antibiotic, was shown to be effective in vitroagainst Pseudomonas, Klebsiella, Staphylococcus aureus, Enterobacter, Proteus mirabilis, indole-positive Proteus, and Eshcherichia coli. It was shown to produce serum and urine concentrations similar to gentamicin when administered intramuscularly. Preliminary animal studies showed this agent to have nephrotoxic and ototoxic effects similar to gentamicin. In our studies, tobramycin was well tolerated and produced only two transient elevations in serum creatinine and no abnormalities in audiograms and vestibular function tests. It was effective in 10 of 12 susceptible infections, including 2 of 4 with Pseudomonas endocarditis. Tobramycin compared favorably with gentamicin …
Haversian And Endosteal Bone Formation Rates In Rib Biopsies Of 50 Patients With Senile And Postmenopausal Osteoporosis, Kent K. Wu
Henry Ford Hospital Medical Journal
Eleventh rib biopsies of 50 patients with senile and postmenopausal osteoporosis, studied by means of tetracycline bone labeling, revealed significant and similar although modest decreases In bone formation on the cortical-endosteal and haversian surfaces of the biopsies.
Statistics For Clinical Research, W. R. Mccrum
Statistics For Clinical Research, W. R. Mccrum
Henry Ford Hospital Medical Journal
The purpose of this paper is to make understandable the use of statistics in the field of medicine, and to introduce to the clinician some new methods of statistics for drawing some reasonable conclusions based on the meager data usually available. There is, after all, only one valid use of statistics: to enable oneself to make a personal decision based on the information available.
Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research
Henry Ford Hospital Medical Journal
No abstract provided.
Frank J. Sladen 1882-1973, Enisse Chimes
Frank J. Sladen 1882-1973, Enisse Chimes
Henry Ford Hospital Medical Journal
No abstract provided.
Primary Biliary Cirrhosis With Systemic Sclerosis, Pedro A. Diaz, Bernard M. Schuman
Primary Biliary Cirrhosis With Systemic Sclerosis, Pedro A. Diaz, Bernard M. Schuman
Henry Ford Hospital Medical Journal
Two patients with combinedbilian/ cirrhosis and scleroderma are described. Both patients also presented features of the CRST syndrome, namely Raynaud's phenomenon, and telangiectasiae. Nine previously reported cases are reviewed and the clinical data suggest that a common underlying immunologic basis may account for both clinical conditions.
The Involvement Of Urinary Kallikrein In The Renal Escape From The Sodium Retaining Effect Of Mineralocorticoids, M. Marin-Grez, N. B. Oza, Oscar A. Carretero
The Involvement Of Urinary Kallikrein In The Renal Escape From The Sodium Retaining Effect Of Mineralocorticoids, M. Marin-Grez, N. B. Oza, Oscar A. Carretero
Henry Ford Hospital Medical Journal
It is well known that the normal kidney "escapes" the sodium retaining effect of mineralocorticoids. However, the mechanism that mediates this "escape" is not understood. The possible role of kallikrein in this "escape" phenomenon was investigated by placing seven dogs in metabolic cages and giving them a constant sodium diet. After they had been on this diet three days, urine was collected for two 24-hour periods. DOCA (25 mg/day) was then given intramuscularly for five days. Urine was collected daily during this DOCA period and for two additional 24- hour periods. Urine volume, sodium, potassium, protein, and kallikrein excretion were …
The Scanning Electron Microscope: Applications At The Edsel B. Ford Institute For Medical Research, John H. L. Watson
The Scanning Electron Microscope: Applications At The Edsel B. Ford Institute For Medical Research, John H. L. Watson
Henry Ford Hospital Medical Journal
The Henry Ford Hospital with its research partner, The Edsel B. Ford Institute for Medical Research, was the first private medical center in the State of Michigan to purchase a scanning electron microscope and to begin to apply it, a year ago, to the study of medical and biological problems in both the animal and the human. This article briefly describes how the instrument works and shows some samples of micrographs produced.
Complications Of Treated Cushing's Syndrome, Lewis B. Morrow, Raymond C. Mellinger, M. Saeed Zafar, Richmond W. Smith Jr.
Complications Of Treated Cushing's Syndrome, Lewis B. Morrow, Raymond C. Mellinger, M. Saeed Zafar, Richmond W. Smith Jr.
Henry Ford Hospital Medical Journal
Fifty-two patients with Cushing's syndrome are reported with emphasis on post treatment complications. Seven patients, cured of their disease following appropriate therapy, had a recurrence of adrenal hypersecretion from one to ten years later. This occurred after all modalities of treatment, but was more common after sub-total adrenalectomy. Pituitary adenomas were found in two cases. Pseudotumor cerebri, psychiatnc complications, hyperthyroidism and hyperpigmentation were observed. One patient developed progressive hyperplgmentation despite pituitary radiation. Thirteen of fifty-two patients had malignant disease including three endometrial carcinomas, one rectal carcinoma and one adenocarcinoma of the mandible. Despite the remarkable improvement In the prognosis for …
Publications Of The Staff Of The Henry Ford Hospital And The Edsel B. Ford Institute For Medical Research
Henry Ford Hospital Medical Journal
No abstract provided.
Experience With Cleft Lip And Palate At The Henry Ford Hospital, W. Peter Mccabe
Experience With Cleft Lip And Palate At The Henry Ford Hospital, W. Peter Mccabe
Henry Ford Hospital Medical Journal
A detailed analysis is presented of 321 patients with clefts of the lip and/or palate treated at Henry Ford Hospital. Comments are made on past and future trends in the management of these complex entities.
Toxic Megacolon In Granulomatous Colitis, K. Anselm, S. A. Rosenblum, V. De Marco
Toxic Megacolon In Granulomatous Colitis, K. Anselm, S. A. Rosenblum, V. De Marco
Henry Ford Hospital Medical Journal
Acute, toxic dilatation of the colon in granulomatous colitis occurs more frequently than heretofore reported, and is a more serious complication than its counterpart in ulcerative colitis. Twenty-six patients who had toxic megacolon were seen at the Henry Ford Hospital between 1961 and 1971. Fourteen of these had ulcerative colitis and 12 had granulomatous colitis. Coricosteroids were relatively ineffective in these 12 patients and all but two needed surgical intervention. Postoperative complications occurred in two cases, with two deaths. Although the initial clinical picture between the two conditions is identical, the clinical course In those with granulomatous colitis is more …
Concomitant Streptococcal Endocarditis And Tuberculous Pleuro-Pericardial Effusion, T. Madhavan, Evelyn J. Fisher, Frank Cox Jr., Edward L. Quinn
Concomitant Streptococcal Endocarditis And Tuberculous Pleuro-Pericardial Effusion, T. Madhavan, Evelyn J. Fisher, Frank Cox Jr., Edward L. Quinn
Henry Ford Hospital Medical Journal
No abstract provided.