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Full-Text Articles in Life Sciences

Pasnet: Pathway-Associated Sparse Deepneural Network For Prognosis Prediction From High-Throughput Data, Jie Hao, Youngsoon Kim, Tae-Kyung Kim, Mingon Kang Dec 2018

Pasnet: Pathway-Associated Sparse Deepneural Network For Prognosis Prediction From High-Throughput Data, Jie Hao, Youngsoon Kim, Tae-Kyung Kim, Mingon Kang

Faculty Publications

Background: Predicting prognosis in patients from large-scale genomic data is a fundamentally challenging problem in genomic medicine. However, the prognosis still remains poor in many diseases. The poor prognosis maybe caused by high complexity of biological systems, where multiple biological components and their hierarchical relationships are involved. Moreover, it is challenging to develop robust computational solutions with high-dimension, low-sample size data. Results: In this study, we propose a Pathway-Associated Sparse Deep Neural Network (PASNet) that not only predicts patients’ prognoses but also describes complex biological processes regarding biological pathways for prognosis. PASNet models a multilayered, hierarchical biological system of genes ...


Micrat: A Novel Algorithm For Inferring Gene Regulatory Networks Using Time Series Gene Expression Data, Bei Yang, Yaohui Xu, Andrew Maxwell, Wonryull Koh, Ping Gong, Chaoyang Zhang Dec 2018

Micrat: A Novel Algorithm For Inferring Gene Regulatory Networks Using Time Series Gene Expression Data, Bei Yang, Yaohui Xu, Andrew Maxwell, Wonryull Koh, Ping Gong, Chaoyang Zhang

Faculty Publications

Background

Reconstruction of gene regulatory networks (GRNs), also known as reverse engineering of GRNs, aims to infer the potential regulation relationships between genes. With the development of biotechnology, such as gene chip microarray and RNA-sequencing, the high-throughput data generated provide us with more opportunities to infer the gene-gene interaction relationships using gene expression data and hence understand the underlying mechanism of biological processes. Gene regulatory networks are known to exhibit a multiplicity of interaction mechanisms which include functional and non-functional, and linear and non-linear relationships. Meanwhile, the regulatory interactions between genes and gene products are not spontaneous since various processes ...


Rhizosphere Microbial Communities Of Spartina Alternifloa And Juncus Roemerianus From Restored And Natural Tidal Marshes On Deer Island, Mississippi, Olga Mavrodi, Carina M. Jung, Jed O. Eberly, Samuel Hendry, Sanchirmaa Namijilsuren, Patrick D. Biber, Karl J. Indest, Dmitri V. Mavrodi Dec 2018

Rhizosphere Microbial Communities Of Spartina Alternifloa And Juncus Roemerianus From Restored And Natural Tidal Marshes On Deer Island, Mississippi, Olga Mavrodi, Carina M. Jung, Jed O. Eberly, Samuel Hendry, Sanchirmaa Namijilsuren, Patrick D. Biber, Karl J. Indest, Dmitri V. Mavrodi

Faculty Publications

The U. S. Gulf of Mexico is experiencing a dramatic increase in tidal marsh restoration actions, which involves planting coastal areas with smooth cordgrass (Spartina alterniflora) and black needlerush (Juncus roemerianus) for erosion control and to provide habitat for fish and wildlife. It can take decades for sedimentary cycles in restored marshes to approach reference conditions, and the contribution of the sediment microbial communities to these processes is poorly elucidated. In this study, we addressed this gap by comparing rhizosphere microbiomes of S. alterniflora and J. roemerianus from two restored marshes and a natural reference marsh located at Deer Island ...


Multiple Environmental Stressors Induce Complex Transcriptomic Responses Indicative Of Phenotypic Outcomes In Western Fence Lizard, Kurt A. Gust, Vijender Chaitankar, Preetam Ghosh, Mitchell S. Wilbanks, Xianfeng Chen, Natalie D. Barker, Don Pham, Leona D. Scanlan, Arun Rawat, Larry G. Talent, Michael J. Quinn Jr., Christopher D. Vulpe, Mohamed O. Elasri, Mark S. Johnson, Edward J. Perkins, Craig A. Mcfarland Dec 2018

Multiple Environmental Stressors Induce Complex Transcriptomic Responses Indicative Of Phenotypic Outcomes In Western Fence Lizard, Kurt A. Gust, Vijender Chaitankar, Preetam Ghosh, Mitchell S. Wilbanks, Xianfeng Chen, Natalie D. Barker, Don Pham, Leona D. Scanlan, Arun Rawat, Larry G. Talent, Michael J. Quinn Jr., Christopher D. Vulpe, Mohamed O. Elasri, Mark S. Johnson, Edward J. Perkins, Craig A. Mcfarland

Faculty Publications

Background

The health and resilience of species in natural environments is increasingly challenged by complex anthropogenic stressor combinations including climate change, habitat encroachment, and chemical contamination. To better understand impacts of these stressors we examined the individual- and combined-stressor impacts of malaria infection, food limitation, and 2,4,6-trinitrotoluene (TNT) exposures on gene expression in livers of Western fence lizards (WFL, Sceloporus occidentalis) using custom WFL transcriptome-based microarrays.

Results

Computational analysis including annotation enrichment and correlation analysis identified putative functional mechanisms linking transcript expression and toxicological phenotypes. TNT exposure increased transcript expression for genes involved in erythropoiesis, potentially in response ...


Autophagy And Aging: Maintaining The Proteome Through Exercise And Caloric Restriction, Kurt A. Escobar, Nathan H. Cole, Christine M. Mermier, Trisha A. Vandusseldrop Nov 2018

Autophagy And Aging: Maintaining The Proteome Through Exercise And Caloric Restriction, Kurt A. Escobar, Nathan H. Cole, Christine M. Mermier, Trisha A. Vandusseldrop

Faculty Publications

Accumulation of dysfunctional and damaged cellular proteins and organelles occursduring aging, resulting in a disruption of cellular homeostasis and progressive degen-eration and increases the risk of cell death. Moderating the accrual of these defunctcomponents is likely a key in the promotion of longevity. While exercise is knownto promote healthy aging and mitigate age‐related pathologies, the molecular under-pinnings of this phenomenon remain largely unclear. However, recent evidencessuggest that exercise modulates the proteome. Similarly, caloric restriction (CR), aknown promoter of lifespan, is understood to augment intracellular protein quality.Autophagy is an evolutionary conserved recycling pathway responsible for thedegradation, then turnover of ...


Seascape Connectivity Of Gulf Sturgeon Acipenser Oxyrinchus Desotoi Population Units Across The Northern Gulf Of Mexico, Page E. Vick, Mark S. Peterson, William T. Slack Oct 2018

Seascape Connectivity Of Gulf Sturgeon Acipenser Oxyrinchus Desotoi Population Units Across The Northern Gulf Of Mexico, Page E. Vick, Mark S. Peterson, William T. Slack

Faculty Publications

Critical habitat was designated in 2003 for federally threatened anadromous Gulf sturgeon to aid in population recovery. This study examined overwintering Gulf sturgeon spatial use and movement through critical habitat monitored by the Ship Island acoustic array from 2011 to 2015. Previous studies observed western population Gulf sturgeon (Pearl and Pascagoula rivers) overwintering near the ends and within the passes of the barrier islands of the Mississippi Sound, USA. Recent telemetry studies detected eastern population fish (Escambia, Blackwater, Yellow, and Choctawhatchee rivers) overwintering as far west as Mobile Bay, Alabama; however, this study is the first to observe eastern population ...


A 4-Year Analysis Of The Incidence Of Injuries Among Crossfit-Trained Participants, Yuri Feito, Evanette K. Burrows, Loni Phillip Tabb Oct 2018

A 4-Year Analysis Of The Incidence Of Injuries Among Crossfit-Trained Participants, Yuri Feito, Evanette K. Burrows, Loni Phillip Tabb

Faculty Publications

Background: High-intensity functional training (HIFT) is a new training modality that merges high-intensity exercise with functional (multijoint) movements. Even though others exist, CrossFit training has emerged as the most common form of HIFT. Recently, several reports have linked CrossFit training to severe injuries and/or life-threatening conditions, such as rhabdomyolysis.Empirical evidence regarding the safety of this training modality is currently limited. Purpose: To examine the incidence of injuries related to CrossFit participation and to estimate the rate of injuries in a large cross-sectional convenience sample of CrossFit participants from around the world. Study Design: Descriptive epidemiology study. Methods: A ...


Effects Of Coumaphos And Imidacloprid On Honey Bee (Hymenoptera: Apidae) Lifespan And Antioxidant Gene Regulations In Laboratory Experiments, Ales Gregorc, Mohamed Alburaki, Nicholas Rinderer, Blair Sampson, Patricia R. Knight, Shahid Karim, John Adamczyk Oct 2018

Effects Of Coumaphos And Imidacloprid On Honey Bee (Hymenoptera: Apidae) Lifespan And Antioxidant Gene Regulations In Laboratory Experiments, Ales Gregorc, Mohamed Alburaki, Nicholas Rinderer, Blair Sampson, Patricia R. Knight, Shahid Karim, John Adamczyk

Faculty Publications

The main objective of this study was to test comparatively the effects of two common insecticides on honey bee Apis mellifera worker’s lifespan, food consumption, mortality, and expression of antioxidant genes. Newly emerged worker bees were exposed to organophosphate insecticide coumaphos, a neonicotinoid imidacloprid, and their mixtures. Toxicity tests were conducted along with bee midgut immunohistological TUNEL analyses. RT-qPCR assessed the regulation of 10 bee antioxidant genes linked to pesticide toxicity. We tested coumaphos at 92,600 ppb concentration, in combination with 5 and 20 ppb imidacloprid. Coumaphos induced significantly higher bee mortality, which was associated with down regulation ...


Effect Of Branched-Chain Amino Acid Supplementationon Recovery Following Acute Eccentric Exercise, Trisha A. Vandusseldorp, Kurt A. Escobar, Kelly E. Johnson, Matthew T. Stratton, Terence Moriarty, Nathan Cole, James J. Mccormick, Chad M. Kersick, Roger A. Vaughan, Karol Dokladny, Len Kravitz, Christine M. Mermier Oct 2018

Effect Of Branched-Chain Amino Acid Supplementationon Recovery Following Acute Eccentric Exercise, Trisha A. Vandusseldorp, Kurt A. Escobar, Kelly E. Johnson, Matthew T. Stratton, Terence Moriarty, Nathan Cole, James J. Mccormick, Chad M. Kersick, Roger A. Vaughan, Karol Dokladny, Len Kravitz, Christine M. Mermier

Faculty Publications

This study investigated the effect of branched-chain amino acid (BCAA) supplementationon recovery from eccentric exercise. Twenty males ingested either a BCAA supplement or placebo(PLCB) prior to and following eccentric exercise. Creatine kinase (CK), vertical jump (VJ), maximalvoluntary isometric contraction (MVIC), jump squat (JS) and perceived soreness were assessed.No significant (p> 0.05) group by time interaction effects were observed for CK, soreness, MVIC, VJ,or JS. CK concentrations were elevated above baseline (p< 0.001) in both groups at 4, 24, 48 and 72 hr,while CK was lower (p= 0.02) in the BCAA group at 48 hr compared to PLCB. Soreness increasedsignificantly from baseline (p< 0.01) in both groups at all time-points; however, BCAA supplementedindividuals reported less soreness (p< 0.01) at the 48 and 72 hr time-points. MVIC force outputreturned to baseline levels (p> 0.05) at 24, 48 and 72 hr for BCAA individuals. No significant differencebetween groups (p> 0.05) was detected for VJ or JS. BCAA ...


Lipopolysaccharide‐Induced Inflammation Does Not Alter Muscle Spindle Afferent Mechanosensation Or Sensory Integration In The Spinal Cord Of Adult Mice, Dasha Zaytseva, Anusha Allawala, Joy Franco, Shea Putnam, Adam Abtahie, Nina Bubalo, Connor Criddle, Tuan Nguyen, Peter Nguyen, Shreejit Padmanabhan, Puneet Sanghera, Martina Bremer, Tzvia Abramson, Katherine A. Wilkinson Sep 2018

Lipopolysaccharide‐Induced Inflammation Does Not Alter Muscle Spindle Afferent Mechanosensation Or Sensory Integration In The Spinal Cord Of Adult Mice, Dasha Zaytseva, Anusha Allawala, Joy Franco, Shea Putnam, Adam Abtahie, Nina Bubalo, Connor Criddle, Tuan Nguyen, Peter Nguyen, Shreejit Padmanabhan, Puneet Sanghera, Martina Bremer, Tzvia Abramson, Katherine A. Wilkinson

Faculty Publications

Inflammation is known to alter nervous system function, but its effect on muscle spindle afferent mechanosensation and sensory integration in the spinal cord has not been well studied. We tested the hypothesis that systemic inflammation induced by an intraperitoneal injection of the endotoxin lipopolysaccharide (LPS; 7.5 × 105 endotoxin units/kg 18 h before experiment) would alter muscle spindle afferent mechanosensation and spinal cord excitability to Group Ia input in male and female adult C57Bl/6 mice. LPS injection caused a systemic immune response, evidenced by decreased white blood cell, monocyte, and lymphocyte concentrations in the blood, increased blood granulocyte ...


Resistance Training Does Not Induce Uniform Adaptations To Quadriceps, Gerald T. Mangine, Michael J. Redd, Adam M. Gonzalez, Jeremy R. Townsend, Adam J. Wells, Adam R. Jajtner, Kyle S. Beyer, Carleigh H. Boone, Michael B. La Monica, Jeffrey R. Stout, David H. Fukuda, Nicholas R. Ratamess, Jay R. Hoffman Aug 2018

Resistance Training Does Not Induce Uniform Adaptations To Quadriceps, Gerald T. Mangine, Michael J. Redd, Adam M. Gonzalez, Jeremy R. Townsend, Adam J. Wells, Adam R. Jajtner, Kyle S. Beyer, Carleigh H. Boone, Michael B. La Monica, Jeffrey R. Stout, David H. Fukuda, Nicholas R. Ratamess, Jay R. Hoffman

Faculty Publications

Resistance training may differentially affect morphological adaptations along the length of uni-articular and bi-articular muscles. The purpose of this study was to compare changes in muscle morphology along the length of the rectus femoris (RF) and vastus lateralis (VL) in response to resistance training. Following a 2-wk preparatory phase, 15 resistance-trained men (24.0 ± 3.0 y, 90.0 ± 13.8 kg, 174.9 ± 20.7 cm) completed pre-training (PRE) assessments of muscle thickness (MT), pennation angle (PA), cross-sectional area (CSA), and echo-intensity in the RF and VL at 30, 50, and 70% of each muscle’s length; fascicle length ...


Normative Values For Self-Reported Benchmark Workout Scores In Crossfit® Practitioners, Gerald T. Mangine, Brant Cebulla, Yuri Feito Aug 2018

Normative Values For Self-Reported Benchmark Workout Scores In Crossfit® Practitioners, Gerald T. Mangine, Brant Cebulla, Yuri Feito

Faculty Publications

Background: CrossFit® practitioners commonly track progress by monitoring their ability to complete a variety of standardized benchmark workouts within a typical class setting. However, objective assessment of progress is challenging because normative data does not currently exist for any of these benchmark workouts. Therefore, the purpose of this study was to develop normative values for five common benchmark workouts (i.e., Fran, Grace, Helen, Filthy-50 [F50], and Fight-Gone-Bad [FGB]). Methods: Performance data from 133,857 male (M) and female (F) profiles located on a publicly available website were collected and sorted by sex (i.e., male [M] and female [F ...


The Tick Endosymbiont Candidatus Midichloria Mitochondrii And Selenoproteins Are Essential For The Growth Of Rickettsia Parkeri In The Gulf Coast Tick Vector, Khemraj Budachetri, Deepak Kumar, Gary Crispell, Christine Beck, Gregory Dasch, Shahid Karim Aug 2018

The Tick Endosymbiont Candidatus Midichloria Mitochondrii And Selenoproteins Are Essential For The Growth Of Rickettsia Parkeri In The Gulf Coast Tick Vector, Khemraj Budachetri, Deepak Kumar, Gary Crispell, Christine Beck, Gregory Dasch, Shahid Karim

Faculty Publications

Background

Pathogen colonization inside tick tissues is a significant aspect of the overall competence of a vector. Amblyomma maculatum is a competent vector of the spotted fever group rickettsiae, Rickettsia parkeri. When R. parkeri colonizes its tick host, it has the opportunity to dynamically interact with not just its host but with the endosymbionts living within it, and this enables it to modulate the tick’s defenses by regulating tick gene expression. The microbiome in A. maculatum is dominated by two endosymbiont microbes: a Francisella-like endosymbiont (FLE) and CandidatusMidichloria mitochondrii (CMM). A range of selenium-containing proteins (selenoproteins) in ...


Congenital Zika Virus Infection In Immunocompetent Mice Causes Postnatal Growth Impediment And Neurobehavioral Deficits, Fengwei Bai, Amber Paul, Dhiraj Acharya, Biswas Neupane, E.A. Thompson, Gabriel Gonzalez-Fernandez, Katherine Copeland, Melanae Garrett, Haibei Liu, Mariper Lopez, Matthew De Cruz, Alex S. Flynt, Jun Liao, Yan-Lin Guo, Federico Gonzalez-Fernandez, Parminder Vig Aug 2018

Congenital Zika Virus Infection In Immunocompetent Mice Causes Postnatal Growth Impediment And Neurobehavioral Deficits, Fengwei Bai, Amber Paul, Dhiraj Acharya, Biswas Neupane, E.A. Thompson, Gabriel Gonzalez-Fernandez, Katherine Copeland, Melanae Garrett, Haibei Liu, Mariper Lopez, Matthew De Cruz, Alex S. Flynt, Jun Liao, Yan-Lin Guo, Federico Gonzalez-Fernandez, Parminder Vig

Faculty Publications

A small percentage of babies born to Zika virus (ZIKV)-infected mothers manifest severe defects at birth, including microcephaly. Among those who appeared healthy at birth, there are increasing reports of postnatal growth or developmental defects. However, the impact of congenital ZIKV infection in postnatal development is poorly understood. Here, we report that a mild congenital ZIKV-infection in pups born to immunocompetent pregnant mice did not display apparent defects at birth, but manifested postnatal growth impediments and neurobehavioral deficits, which include reduced locomotor and cognitive deficits that persisted into adulthood. We found that the brains of these pups were smaller ...


The Gut Microbiome And Aquatic Toxicology: An Emerging Concept For Environmental Health, Ondrej Adamovsky, Amanda Buerger, Alexis M. Wormington, Naomi Ector, Robert J. Griffitt, Joseph H. Bisesi Jr., Christopher J. Martyniuk Aug 2018

The Gut Microbiome And Aquatic Toxicology: An Emerging Concept For Environmental Health, Ondrej Adamovsky, Amanda Buerger, Alexis M. Wormington, Naomi Ector, Robert J. Griffitt, Joseph H. Bisesi Jr., Christopher J. Martyniuk

Faculty Publications

The microbiome plays an essential role in the health and onset of diseases in all animals, including humans. The microbiome has emerged as a central theme in environmental toxicology, as microbes interact with the host immune system in addition to its role in chemical detoxification. Pathophysiological changes in the gastrointestinal tissue caused by ingested chemicals, and metabolites generated from microbial biodegradation, can lead to systemic adverse effects. This critical review dissects what we know about the impacts of environmental contaminants on the microbiome of aquatic species, with special emphasis on the gut microbiome. We highlight some of the known major ...


High-Intensity Functional Training (Hift): Definitionand Research Implications For Improved Fitness, Yuri Feito, Katie M. Heinrich, Scotty J. Butcher, Walker S. Carlos Poston Aug 2018

High-Intensity Functional Training (Hift): Definitionand Research Implications For Improved Fitness, Yuri Feito, Katie M. Heinrich, Scotty J. Butcher, Walker S. Carlos Poston

Faculty Publications

High-intensity functional training (HIFT) is an exercise modality that emphasizes functional,multi-joint movements that can be modified to any fitness level and elicit greater muscle recruitmentthan more traditional exercise. As a relatively new training modality, HIFT is often compared tohigh-intensity interval training (HIIT), yet the two are distinct. HIIT exercise is characterized byrelatively short bursts of repeated vigorous activity, interspersed by periods of rest or low-intensityexercise for recovery, while HIFT utilizes constantly varied functional exercises and various activitydurations that may or may not incorporate rest. Over the last decade, studies evaluating theeffectiveness of HIIT programs have documented improvements in metabolic ...


Mood State Changes Accompanying The Crossfitopen™ Competition In Healthy Adults, Allyson G. Box, Yuri Feito, Steven J. Petruzzello, Gerald T. Mangine Jul 2018

Mood State Changes Accompanying The Crossfitopen™ Competition In Healthy Adults, Allyson G. Box, Yuri Feito, Steven J. Petruzzello, Gerald T. Mangine

Faculty Publications

Background: Specific mood states were examined during the CrossFit Open, a consecutive 5-week fitness competition involving five separate CrossFit®workouts, to determine whether the unique design or strenuous workouts of the competition resulted in acute and/or chronic mood statealterations. Methods: Participants (n= 8) completed the Profile of Mood States (POMS) questionnaire one-week prior to the competition (baseline), prior to (PRE), immediately post (IP), 30-min post-(30P) and 60-min post-workout (60P) each week. Tension, depression, anger, confusion, fatigue and vigor were derived from the POMS, as was Total Mood Disturbance (TMD) and an Energy Index (EI). Results: Workout intensity exceeded ...


Testosterone And Cortisol Responses To Fivehigh-Intensity Functional Training Competitionworkouts In Recreationally Active Adults, Gerald T. Mangine, Trisha A. Vandusseldorp, Yuri Feito, Alyssa J. Holmes, Paul R. Serafini, Allyson G. Box, Adam M. Gonzalez Jul 2018

Testosterone And Cortisol Responses To Fivehigh-Intensity Functional Training Competitionworkouts In Recreationally Active Adults, Gerald T. Mangine, Trisha A. Vandusseldorp, Yuri Feito, Alyssa J. Holmes, Paul R. Serafini, Allyson G. Box, Adam M. Gonzalez

Faculty Publications

To determine the salivary steroid response to high-intensity functional training (HIFT)competition workouts, saliva samples were collected from ten recreationally trained male and femalecompetitors during a 5-week (WK1–WK5) international competition. Competitors arrived at theirlocal affiliate and provided samples prior to (PRE) their warm-up, immediately (IP), 30-min (30P),and 60-min (60P) post-exercise. Samples were analyzed for concentrations of testosterone (T), cortisol(C), and their ratio (TC). Generalized linear mixed models with repeated measures revealed significantmain effects for time (p< 0.001) for T, C, and TC. Compared to PRE-concentrations, elevated (p< 0.05)T was observed at IP on WK2–WK5 (mean difference: 135–511 pg·mL−1), at 30P on WK3 (meandifference: 81.0±30.1 pg·mL−1) and WK5 (mean difference: 56.6±22.7 pg·mL−1), and at 60P onWK3 (mean difference: 73.5±29.7 pg·mL−1) and WK5 (mean difference: 74.3±28.4 pg·mL−1).Compared to PRE-concentrations, elevated (p< 0.05) C was noted on all weeks at IP (mean difference:9.3–15.9 ng·mL−1) and 30P (mean difference: 6.0–19.9 ng·mL−1); significant (p< 0.006) elevationswere noted at 60P on WK1 (mean difference: 9.1±3.0 ng·mL−1) and WK5 (mean difference:12.8±2.9 ng·mL−1). Additionally, TC was significantly reduced from PRE-values by 61% on WK1 at60P (p= 0.040) and by 80% on WK5 at 30P (p= 0.023). Differences in T, C, and TC were also observedbetween weeks at specific time points. Although each workout affected concentrations in T, C, and/orthe TC ratio, changes appeared to be modulated by the presence of overload and workout duration.During periods of elevated training or competition, athletes and coaches may consider monitoringthese hormones for consistency and as a means of assessing workout difficulty.


Physiological Responses Of Species To Microclimate Help Explain Population Dynamics Along Succession In A Tropical Dry Forest Of Yucatan, Mexico, Paula C. Jackson, José Luis Andrade, Casandra Reyes-García, Olivia Hernández-González, Thomas C. Mcelroy, Roberth Us-Santamaría, José Luis Simá, Juan Manuel Dupuy Jul 2018

Physiological Responses Of Species To Microclimate Help Explain Population Dynamics Along Succession In A Tropical Dry Forest Of Yucatan, Mexico, Paula C. Jackson, José Luis Andrade, Casandra Reyes-García, Olivia Hernández-González, Thomas C. Mcelroy, Roberth Us-Santamaría, José Luis Simá, Juan Manuel Dupuy

Faculty Publications

We investigated relationships between population dynamics and microclimate, physiology, and the degree of mycorrhizal colonization, for three species (Piscidia piscipula L.(Sarg.)) (Fabaceae), Bunchosia swartzianaGriseb. (Malpighiaceae) and Psidium sartorianum (Bergius) Nied. (Myrtaceae)) of a tropical sub deciduous forest in Yucatan, Mexico that were growing in plots of different successional ages. We hypothesized that abundance and persistence were related to increased plasticity in CO2assimilation. We found that Piscidia piscipula had greater abundance in intermediate plots (18 to 21 years), presented higher levels of plasticity in CO2 assimilation (greater variability among individuals, plots, and seasons), presented the highest CO2 assimilation rates, and ...


Plasticity Of Foraging Behaviors In Response To Diverse Environmental Conditions, Morgan Gilmour, José Castillo‐Guerrero, Abram Fleishman, Salvador Hernández‐Vázquez, Hillary Young, Scott Shaffer Jul 2018

Plasticity Of Foraging Behaviors In Response To Diverse Environmental Conditions, Morgan Gilmour, José Castillo‐Guerrero, Abram Fleishman, Salvador Hernández‐Vázquez, Hillary Young, Scott Shaffer

Faculty Publications

Due to rapidly changing global environmental conditions, many animals are now experiencing concurrent changes in both resource availability and the foraging cues associated with finding those resources. By employing flexible, plastic foraging strategies that use different types of environmental foraging cues, animals could adapt to these novel future environments. To evaluate the extent to which such flexibility and plasticity exist, we analyzed a large dataset of a clade (Sulidae; the boobies) of widespread aerial tropical predators that feed in highly variable marine habitats. These surface foragers are typical of many ocean predators that face dynamic and patchy foraging environments and ...


Combined Effects Of Deepwater Horizon Crude Oil And Environmental Stressors On Fundulus Grandis Embryos, Maria L. Rodgers, Elizabeth R. Jones, Christopher Klinkhamer, Cecon T. Mahapatra, Jennifer Serafin, Thijs Bosker, Chris Perkins, Robert J. Griffitt, Sylvain De Guise, Maria S. Sepúlveda Jul 2018

Combined Effects Of Deepwater Horizon Crude Oil And Environmental Stressors On Fundulus Grandis Embryos, Maria L. Rodgers, Elizabeth R. Jones, Christopher Klinkhamer, Cecon T. Mahapatra, Jennifer Serafin, Thijs Bosker, Chris Perkins, Robert J. Griffitt, Sylvain De Guise, Maria S. Sepúlveda

Faculty Publications

In the present study, we examined how sensitivity to oil changes in combination with environmental stressors in Fundulus grandis embryos. We exposed embryos (fertilization) to a range of high‐energy water accommodated fraction (HEWAF) concentrations (0–50 parts per billion [ppb] total polycyclic aromatic hydrocarbons [PAHs]) made from Macondo crude oil in conjunction with various environmental conditions (temperature: 20 and 30 °C; salinity: 3, 7, and 30 practical salinity units [PSU]; and dissolved oxygen: 2 and 6 mg/L). Endpoints included mortality, hatching rates, and expression of cytochrome p450 1a and 1c (cyp1a, cyp1c) in hatched larvae. There was 100 ...


Seasonal Patterns In Phytoplankton Biomass Across The Northern And Deep Gulf Of Mexico: A Numerical Model Study, Fabian A. Gomez, Sang-Ki Lee, Yanyun Liu, Frank J. Hernandez Jr., Frank E. Muller-Karger, John T. Lamkin Jun 2018

Seasonal Patterns In Phytoplankton Biomass Across The Northern And Deep Gulf Of Mexico: A Numerical Model Study, Fabian A. Gomez, Sang-Ki Lee, Yanyun Liu, Frank J. Hernandez Jr., Frank E. Muller-Karger, John T. Lamkin

Faculty Publications

Biogeochemical models that simulate realistic lower-trophic-level dynamics, including the representation of main phytoplankton and zooplankton functional groups, are valuable tools for improving our understanding of natural and anthropogenic disturbances in marine ecosystems. Pre- vious three-dimensional biogeochemical modeling studies in the northern and deep Gulf of Mexico (GoM) have used only one phytoplankton and one zooplankton type. To advance our modeling capability of the GoM ecosystem and to investigate the dominant spatial and seasonal patterns of phytoplank- ton biomass, we configured a 13-component biogeochemical model that explicitly represents nanophytoplankton, diatoms, micro-, and mesozooplankton. Our model outputs compare reasonably well with observed ...


Changes In Body Composition, Bone Metabolism, Strength, And Skill-Specific Performance Resulting From 16-Weeks Of Hift, Yuri Feito, Wade Hoffstetter, Paul Serafini, Gerald Mangine Jun 2018

Changes In Body Composition, Bone Metabolism, Strength, And Skill-Specific Performance Resulting From 16-Weeks Of Hift, Yuri Feito, Wade Hoffstetter, Paul Serafini, Gerald Mangine

Faculty Publications

High Intensity Functional Training (HIFT) is a training modality, characterized by multimodal exercises performed at high-intensity. Little is known about the training adaptations that occur as a prolonged training program. The purpose of this study was to examine changes in body composition, bone metabolism, strength, and skill-specific performance over 16-weeks of HIFT. Twenty-six recreationally active adult males (n = 9; 34.2 ± 9.1 y; 91.5 ± 17.7 kg; 178.5 ± 5.4 cm) and females (n = 17 = 36.4 ± 7.9 y; 91.5 ± 17.7 kg; 162.9 ± 7.0 cm) completed pre and post training assessments of ...


Stability, Persistence And Habitat Associations Of The Pearl Darter Percina Aurora In The Pascagoula River System, Southeastern Usa, Scott R. Clark, William T. Slack, Brian Kreiser, Jacob F. Schaefer, Mark A. Dugo Jun 2018

Stability, Persistence And Habitat Associations Of The Pearl Darter Percina Aurora In The Pascagoula River System, Southeastern Usa, Scott R. Clark, William T. Slack, Brian Kreiser, Jacob F. Schaefer, Mark A. Dugo

Faculty Publications

The southeastern United States represents one of the richest collections of aquatic biodiversity worldwide; however, many of these taxa are under an increasing threat of imperilment, local extirpation, or extinction. The pearl darter Percina aurora is a small-bodied freshwater fish endemic to the Pearl and Pascagoula river systems of Mississippi and Louisiana (USA). The last collected specimen from the Pearl River drainage was taken in 1973, and it now appears that populations in this system are likely extirpated. This reduced the historical range of this species by approximately 50%, ultimately resulting in federal protection under the US Endangered Species Act ...


Exposure To Crude Oil And Chemical Dispersant May Impact Marine Microbial Biofilm Composition And Steel Corrosion, Jennifer Salerno, Brenda Little, Jason Lee, Leila J. Hamdan Jun 2018

Exposure To Crude Oil And Chemical Dispersant May Impact Marine Microbial Biofilm Composition And Steel Corrosion, Jennifer Salerno, Brenda Little, Jason Lee, Leila J. Hamdan

Faculty Publications

The release of hydrocarbons and chemical dispersant in marine environments may disrupt benthic ecosystems, including artificial reefs, formed by historic steel shipwrecks, and their associated organisms. Experiments were performed to determine the impacts of crude oil, dispersed crude oil, and dispersant on the community structure and function of microorganisms in seawater (SW) and biofilms formed on carbon steel, a common ship hull construction material. Steel corrosion was also monitored to illustrate how oil spills may impact preservation of steel shipwrecks. Microcosms were filled with seawater (SW) and incubated at 4°C. Carbon steel disks (CSDs) were placed in each tank ...


Variation In Mating Dynamics Across Five Species Of Leiobunine Harvestmen (Arachnida: Opliones), Kasey D. Fowler-Finn, Sarah L. Boyer, Raine Ikagawa, Timothy Jeffries, Penelope C. Kahn, Eva M. Larsen, Daniel Lee, Morgan Smeester Jun 2018

Variation In Mating Dynamics Across Five Species Of Leiobunine Harvestmen (Arachnida: Opliones), Kasey D. Fowler-Finn, Sarah L. Boyer, Raine Ikagawa, Timothy Jeffries, Penelope C. Kahn, Eva M. Larsen, Daniel Lee, Morgan Smeester

Faculty Publications

No abstract provided.


Nuptial Gift Chemistry Reveals Convergent Evolution Correlated With Antagonism In Mating Systems Of Harvestmen (Arachnida, Opiliones), Penelope C. Kahn, Dennis D. Cao, Mercedes Burns, Sarah L. Boyer Jun 2018

Nuptial Gift Chemistry Reveals Convergent Evolution Correlated With Antagonism In Mating Systems Of Harvestmen (Arachnida, Opiliones), Penelope C. Kahn, Dennis D. Cao, Mercedes Burns, Sarah L. Boyer

Faculty Publications

Nuptial gifts are material donations given from male to female before or during copulation and are subject to sexual selection in a wide variety of taxa. The harvestman genus Leiobunum has emerged as a model system for understanding the evolution of reproductive morphology and behavior, as transitions between solicitous and antagonistic modes of courtship have occurred multiple times within the lineage and are correlated with convergence in genital morphology. We analyzed the free amino acid content of nuptial gift secretions from five species of Leiobunum using gas chromatography–mass spectrometry. Multivariate analysis of the free amino acid profiles revealed that ...


The Receptor Protein Tyrosine Phosphatase Clr-1 Is Required For Synaptic Partner Recognition, Aruna Varshney, Kelli Benedetti, Katherine Watters, Raakhee Shankar, David Tatarakis, Doris Coto Villa, Khristina Magallanes, Venia Agenor, William Wung, Fatima Farah, Nebat Ali, Nghi Le, Jacqueline Pyle, Amber Farooqi, Zanett Kieu, Martina Bremer, Miri Vanhoven May 2018

The Receptor Protein Tyrosine Phosphatase Clr-1 Is Required For Synaptic Partner Recognition, Aruna Varshney, Kelli Benedetti, Katherine Watters, Raakhee Shankar, David Tatarakis, Doris Coto Villa, Khristina Magallanes, Venia Agenor, William Wung, Fatima Farah, Nebat Ali, Nghi Le, Jacqueline Pyle, Amber Farooqi, Zanett Kieu, Martina Bremer, Miri Vanhoven

Faculty Publications

During neural circuit formation, most axons are guided to complex environments, coming into contact with multiple potential synaptic partners. However, it is critical that they recognize specific neurons with which to form synapses. Here, we utilize the split GFP-based marker Neuroligin-1 GFP Reconstitution Across Synaptic Partners (NLG-1 GRASP) to visualize specific synapses in live animals, and a circuit-specific behavioral assay to probe circuit function. We demonstrate that the receptor protein tyrosine phosphatase (RPTP) clr-1 is necessary for synaptic partner recognition (SPR) between the PHB sensory neurons and the AVA interneurons in C. elegans. Mutations in clr-1/RPTP result in reduced ...


Exotic Properties Of A Voltage-Gated Proton Channel From The Snail Helisoma Trivolvis, Sarah Thomas, Vladimir V. Cherny, Deri Morgan, Liana R. Artinian, Vincent Rehder, Susan M. E. Smith, Thomas E. Decoursey May 2018

Exotic Properties Of A Voltage-Gated Proton Channel From The Snail Helisoma Trivolvis, Sarah Thomas, Vladimir V. Cherny, Deri Morgan, Liana R. Artinian, Vincent Rehder, Susan M. E. Smith, Thomas E. Decoursey

Faculty Publications

Voltage-gated proton channels, HV1, were first reported in Helix aspersa snail neurons. These H+ channels open very rapidly, two to three orders of magnitude faster than mammalian HV1. Here we identify an HV1 gene in the snail Helisoma trivolvis and verify protein level expression by Western blotting of H. trivolvis brain lysate. Expressed in mammalian cells, HtHV1 currents in most respects resemble those described in other snails, including rapid activation, 476 times faster than hHV1 (human) at pHo 7, between 50 and 90 mV. In contrast to most HV1, activation of HtHV1 is exponential, suggesting first-order kinetics. However, the large ...


Histidine168 Is Crucial For Δph-Dependent Gating Of The Human Voltage-Gated Proton Channel, Hhv1, Vladimir V. Cherny, Deri Morgan, Sarah Thomas, Susan M. E. Smith, Thomas E. Decoursey May 2018

Histidine168 Is Crucial For Δph-Dependent Gating Of The Human Voltage-Gated Proton Channel, Hhv1, Vladimir V. Cherny, Deri Morgan, Sarah Thomas, Susan M. E. Smith, Thomas E. Decoursey

Faculty Publications

We recently identified a voltage-gated proton channel gene in the snail Helisoma trivolvis, HtHV1, and determined its electrophysiological properties. Consistent with early studies of proton currents in snail neurons, HtHV1 opens rapidly, but it unexpectedly exhibits uniquely defective sensitivity to intracellular pH (pHi). The H+ conductance (gH)-V relationship in the voltage-gated proton channel (HV1) from other species shifts 40 mV when either pHi or pHo (extracellular pH) is changed by 1 unit. This property, called ΔpH-dependent gating, is crucial to the functions of HV1 in many species and in numerous human tissues. The HtHV1 channel exhibits normal pHo dependence ...