Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 30 of 48
Full-Text Articles in Life Sciences
Comparing Low Salinity Transcriptomic Profiles Among Hard Clam, Mercenaria Mercenaria, Lines, Leslie Speight Youtsey
Comparing Low Salinity Transcriptomic Profiles Among Hard Clam, Mercenaria Mercenaria, Lines, Leslie Speight Youtsey
Dissertations, Theses, and Masters Projects
The hard clam is an important ecological and economic resource along the U.S. Eastern Seaboard. In Virginia alone, farm gate sales were estimated at $38.8 million in 2018 and $57.8 million in 2021, making Virginia the largest producer of hard clams in the U.S. This industry is primarily limited to higher salinity habitats on the seaside of the Eastern Shore of Virginia and lower Chesapeake Bay. Although the hard clam can be found in lower salinity habitats, they do not grow or survive at rates that are practical for productive aquaculture. Even in areas of higher salinity, hard clams are …
Acetylation Controls Thyroid Hormone Receptor Intracellular Localization And Intranuclear Mobility, Cyril S. Anyetei-Anum
Acetylation Controls Thyroid Hormone Receptor Intracellular Localization And Intranuclear Mobility, Cyril S. Anyetei-Anum
Dissertations, Theses, and Masters Projects
Thyroid hormone receptor (TR) is responsible for mediating the expression of genes involved in growth, development, and homeostatic regulation, in response to thyroid hormone. There are two main subtypes of TR, TRα1 and TRβ1, that mediate these physiological processes. Dysregulation of TR mediated processes is a contributing factor in disease pathology. Our prior studies show that TR is shuttled rapidly between the nucleus and cytosol, while localizing primarily to the nucleus. TRα1 contains two nuclear localization signals (NLSs) that act together to confer strong nuclear localization, while TRβ1 only contains one NLS (NLS-1). Recently, we found that the intracellular localization …
Identifying Sumo Protease Targets And Investigating E3 Ligase Interactions, Mark Guillotte
Identifying Sumo Protease Targets And Investigating E3 Ligase Interactions, Mark Guillotte
Dissertations, Theses, and Masters Projects
No abstract provided.
Investigating Heat Shock Protein 70 As A Binding Partner Of Mk-Styx, And The Role Of Mk-Styx In Neuronal Differentiation, Lauren Elizabeth Rusnak
Investigating Heat Shock Protein 70 As A Binding Partner Of Mk-Styx, And The Role Of Mk-Styx In Neuronal Differentiation, Lauren Elizabeth Rusnak
Dissertations, Theses, and Masters Projects
No abstract provided.
Spe-7, A Novel Regulator Of Msp Assembly In C Elegans Spermatocytes, Kari Lynn Messina
Spe-7, A Novel Regulator Of Msp Assembly In C Elegans Spermatocytes, Kari Lynn Messina
Dissertations, Theses, and Masters Projects
No abstract provided.
An Investigation Of The Polymorphic Arss Gene Of Helicobacter Pylori, Daniel Ross Hallinger
An Investigation Of The Polymorphic Arss Gene Of Helicobacter Pylori, Daniel Ross Hallinger
Dissertations, Theses, and Masters Projects
No abstract provided.
Sumo-Dependent Substrate Targeting Of The Sumo Protease Ulp1, Zachary Cole Elmore
Sumo-Dependent Substrate Targeting Of The Sumo Protease Ulp1, Zachary Cole Elmore
Dissertations, Theses, and Masters Projects
No abstract provided.
Understanding The Origins, Dispersal, And Evolution Of Bonamia Species (Phylum Haplosporidia) Based On Genetic Analyses Of Ribosomal Rna Gene Regions, Kristina M. Hill
Understanding The Origins, Dispersal, And Evolution Of Bonamia Species (Phylum Haplosporidia) Based On Genetic Analyses Of Ribosomal Rna Gene Regions, Kristina M. Hill
Dissertations, Theses, and Masters Projects
No abstract provided.
The Sumo-Targeted Ubiquitin Ligase Subunit Slx5 Functional Interacts With The Sumo E3 Ligase Siz1, Jason William Westerbeck
The Sumo-Targeted Ubiquitin Ligase Subunit Slx5 Functional Interacts With The Sumo E3 Ligase Siz1, Jason William Westerbeck
Dissertations, Theses, and Masters Projects
No abstract provided.
Molecular Marker Development For The Discrimination Of Atlantic And Pacific Blue Marlin (Makaira Nigricans), Laurie Sorenson
Molecular Marker Development For The Discrimination Of Atlantic And Pacific Blue Marlin (Makaira Nigricans), Laurie Sorenson
Dissertations, Theses, and Masters Projects
No abstract provided.
The Pax-5 Gene Is Alternatively Spliced In Trout B Cells, Raaj Mahendra Talauliker
The Pax-5 Gene Is Alternatively Spliced In Trout B Cells, Raaj Mahendra Talauliker
Dissertations, Theses, and Masters Projects
No abstract provided.
Assessing Genetic Variation Within And Among Native Populations And Hatchery Stocks Of Crassostrea Ariakensis Using Microsatellite Markers, Jie Xiao
Dissertations, Theses, and Masters Projects
Assessing genetic variation within and among native populations and hatchery stocks of Crassostrea ariakensis using microsatellite markers In response to the dramatic decline of eastern oyster (Crassostrea virginica) populations in the Chesapeake Bay, introduction of the non-native Asian oyster Crassostrea ariakensis has been proposed. Currently several hatchery stocks of C. ariakensis, derived from a few wild populations along the coast of Japan and China, are being maintained in U.S. hatcheries in the Pacific northwest and on the east coast. In recent years, as the risks of the proposed introduction are being assessed, these hatchery animals have been widely used for …
A Molecular Analysis Of Atlantic Menhaden (Brevoortia Tyrannus) Stock Structure, Abigail J. Lynch
A Molecular Analysis Of Atlantic Menhaden (Brevoortia Tyrannus) Stock Structure, Abigail J. Lynch
Dissertations, Theses, and Masters Projects
Atlantic menhaden is an ecologically and economically important species along the U.S. east coast. As a filter-feeder and key prey fish, it provides a critical link between primary production, phytoplankton, and larger piscivorous predators, such as striped bass, bluefish, and weakfish. The species is also the target of one of the largest commercial fisheries in the country. Menhaden are assessed as a single, coastwide stock, and recent assessments indicate that it is not overfished. However, there is very limited population genetics data to support the assumption of a single stock. Additionally, the recent consolidation of the fishery and localization of …
The Relationship Between Antibody Redox Structure And Affinity In Rainbow Trout, Jianmin Ye
The Relationship Between Antibody Redox Structure And Affinity In Rainbow Trout, Jianmin Ye
Dissertations, Theses, and Masters Projects
Teleost immunoglobulin M (IgM), an 800 kDa tetramer, possesses considerable structural diversity due to the non-uniform disulfide polymerization of its halfmeric or monomeric subunits. However, to date, no plausible functional role for this diversity has been demonstrated or proposed. This research was, therefore, designed to investigate the possible functional role(s) for this diversity using the trout model. The possible relationship between this structural diversity and affinity was specifically addressed. The relationship between high levels of disulfide polymerization and high affinity was demonstrated by selective immunoadsorption and analysis of antibodies isolated during the process of affinity maturation. A pivotal determinative role …
Analysis Of Sequence Variation At Two Helicobacter Pylori Genetic Loci Potentially Involved In Virulence, George Warren Liechti
Analysis Of Sequence Variation At Two Helicobacter Pylori Genetic Loci Potentially Involved In Virulence, George Warren Liechti
Dissertations, Theses, and Masters Projects
No abstract provided.
A Molecular Phylogeny Of The Genus Bonamia Based On Sequence Data Of The Ribosomal Rna (Rrna) Gene Complex, Delonna M. White
A Molecular Phylogeny Of The Genus Bonamia Based On Sequence Data Of The Ribosomal Rna (Rrna) Gene Complex, Delonna M. White
Dissertations, Theses, and Masters Projects
No abstract provided.
A Molecular Study Of The Mitochondrial Genome And Invasions Of The Veined Rapa Whelk, Rapana Venosa, Emily A. Chandler
A Molecular Study Of The Mitochondrial Genome And Invasions Of The Veined Rapa Whelk, Rapana Venosa, Emily A. Chandler
Dissertations, Theses, and Masters Projects
No abstract provided.
A Molecular Technique For Specific Identification Of Western Atlantic Ocean Scombrids And An Analysis Of A Larval Scombrid Assemblage Off The Kona Coast Of Hawaii, Melissa A. Paine
A Molecular Technique For Specific Identification Of Western Atlantic Ocean Scombrids And An Analysis Of A Larval Scombrid Assemblage Off The Kona Coast Of Hawaii, Melissa A. Paine
Dissertations, Theses, and Masters Projects
No abstract provided.
Effects Of Overexpressing Alternative Isoform Pax-5e In Vivo, Suzanne Elizabeth Cole
Effects Of Overexpressing Alternative Isoform Pax-5e In Vivo, Suzanne Elizabeth Cole
Dissertations, Theses, and Masters Projects
No abstract provided.
A Mycobacterium-Inducible Nramp In Striped Bass Morone Saxatilis, Erin Jeffrey Burge
A Mycobacterium-Inducible Nramp In Striped Bass Morone Saxatilis, Erin Jeffrey Burge
Dissertations, Theses, and Masters Projects
In mammals, the natural resistance-associated macrophage protein 1 gene, Nramp1, plays a major role in resistance to mycobacterial infections. Chesapeake Bay (USA) striped bass, Morone saxatilis, are currently experiencing an epizootic of mycobacteriosis that threatens the health of this ecologically and economically important species. This dissertation characterizes an Nramp gene in this species (MsNramp ) and provide evidence for induction following Mycobacterium exposure. The striped bass MsNramp gene and 554 amino acid sequence contain all the signal features of the Nramp family, including a topology of 12 transmembrane domains (TM), the transport protein specific 'binding-protein-dependent transport system inner membrane component …
Synalpheus Shrimp From Carrie Bow Cay, Belize. Systematics, Phylogenetics And Biological Observations (Crustacea: Decapoda: ; Alpheidae), Ruben Rios Gonzalez
Synalpheus Shrimp From Carrie Bow Cay, Belize. Systematics, Phylogenetics And Biological Observations (Crustacea: Decapoda: ; Alpheidae), Ruben Rios Gonzalez
Dissertations, Theses, and Masters Projects
Snapping shrimp in the family Alpheidae are remarkably abundant in coral reef ecosystems worldwide. The second most speciose genus, Synalpheus , includes species usually small and reclusive, and their general morphology is notably uniform, yet the number of species is staggeringly high, as is the intraspecific variability. These features have contributed to a poorly resolved taxonomic status, as evidenced both by recurring lumping and splitting of species and by lack of proper definition of several common species. I examined western Atlantic species of Synalpheus in the large and regionally dominant "Gambarelloides group of species", an informal but widely used guild …
Genetic Variation Within And Among The Suminoe Oyster (Crassostrea Ariakensis) Populations And Stocks As Assessed By Molecular Markers, Qian Zhang
Dissertations, Theses, and Masters Projects
No abstract provided.
Characterization Of The Xgat-1 Gene In Xenopus Laevis, Lisa Layne August
Characterization Of The Xgat-1 Gene In Xenopus Laevis, Lisa Layne August
Dissertations, Theses, and Masters Projects
No abstract provided.
Molecular And Morphological Evolution Of The Amphipod Radiation Of Lake Baikal, Kenneth S. Macdonald Iii
Molecular And Morphological Evolution Of The Amphipod Radiation Of Lake Baikal, Kenneth S. Macdonald Iii
Dissertations, Theses, and Masters Projects
The amphipods of Lake Baikal, Russia, are a taxonomically and morphologically diverse group, and have been cited as a classic example of adaptive radiation. An unfortunate consequence of this diversity has been an instability of Baikal amphipod classification, with frequent revisions spurred by differing opinions about the phylogenetic utility of different characters. Classifications have never been based on a rigorous phylogenetic analysis of morphological data and only recently has the phylogeny of Lake Baikal's amphipods been examined using molecular tools. Unfortunately, most of these studies have led to a limited expansion of our understanding of Baikal amphipod systematics. Phylogenetic relationships …
Genetic Stock Structure Of The Sailfish, Istiophorus Platypterus, Based On Nuclear And Mitochondrial Dna, Jan Renee Mcdowell
Genetic Stock Structure Of The Sailfish, Istiophorus Platypterus, Based On Nuclear And Mitochondrial Dna, Jan Renee Mcdowell
Dissertations, Theses, and Masters Projects
The results of life history studies involving the sailfish, Istiophorus platypterus, from the Atlantic, Pacific, and Indian oceans were reviewed. Results of studies agree on several aspects of sailfish biology; sailfish exhibit opportunistic feeding behavior, follow the 28??C isotherm, spawn in summer mature at approximately age 3, and are the least migratory of the billfishes. However, results are in conflict concerning sex ratio and whether sailfish are single or multiple spawners. Although many researchers have reported that sailfish are sexually dimorphic, their fragile otoliths make them difficult to age, aging studies have not been validated, and sexual dimorphism has not …
Chromosome Set Instability In 1--2 Year Old Triploid Crassostrea Ariakensis In Multiple Environments, Mingfang Zhou
Chromosome Set Instability In 1--2 Year Old Triploid Crassostrea Ariakensis In Multiple Environments, Mingfang Zhou
Dissertations, Theses, and Masters Projects
No abstract provided.
Molecular Characterization Of Cultured Perkinsus Marinus Isolates, Gwynne D. Brown
Molecular Characterization Of Cultured Perkinsus Marinus Isolates, Gwynne D. Brown
Dissertations, Theses, and Masters Projects
Perkinsus marinus is the causative agent of the oyster disease Dermo in the eastern oyster, Crassostrea virginica. In vitro propagation of the parasite has led to the establishment of multiple isolates by several investigators. Little work, however, has been done to characterize different isolates. In this study multiple isolates were examined for genetic and biochemical diversity. at two loci, the ITS region and the ATAN region, there was as much intra-isolate genetic variation among DNA sequences of some isolates as there was inter-isolate variation. Variation was also observed at a third loci, a subtilisin-like serine protease gene. This is the …
Adrenal Expression Of Cyp17 And Hsd3b1 Mrna In Peromyscus Maniculatus Bairdii, Brian Thomas Lovitt
Adrenal Expression Of Cyp17 And Hsd3b1 Mrna In Peromyscus Maniculatus Bairdii, Brian Thomas Lovitt
Dissertations, Theses, and Masters Projects
No abstract provided.
The Specific Immune Response In Rainbow Trout: Somatic Hypermutation And Vh Gene Utilization, Teresa D. Lewis
The Specific Immune Response In Rainbow Trout: Somatic Hypermutation And Vh Gene Utilization, Teresa D. Lewis
Dissertations, Theses, and Masters Projects
The study of antibody responses in prominent aquaculture species such as the rainbow trout, Oncorhynchus mykiss, can facilitate vaccine development and contribute to producing useful paradigms of adaptive immunity in lower vertebrates. Thus, it is essential to identify genes responsible for antibody responses. In the mouse model, hybridoma technology allows for the association of monoclonal antibodies possessing various affinities for antigen with specific VH sequences, gene family utilization, and other molecular events (i.e. somatic hypermutation) that occur during the specific immune response. The absence of a comparable hybridoma technology in piscine systems has limited similar studies of fish immunogenetics to …
Function And Regulation Of Alternative Isoforms Of The Transcription Factor Pax-5 During B Lymphocyte Differentiation, Marina A. Lowen
Function And Regulation Of Alternative Isoforms Of The Transcription Factor Pax-5 During B Lymphocyte Differentiation, Marina A. Lowen
Dissertations, Theses, and Masters Projects
No abstract provided.