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Articles 1 - 30 of 1875
Full-Text Articles in Life Sciences
Using Conservation Genetics To Inform Reintroduction Of The Endangered Mottled Duskywing (Erynnis Martialis), Shayla Kroeze
Using Conservation Genetics To Inform Reintroduction Of The Endangered Mottled Duskywing (Erynnis Martialis), Shayla Kroeze
Electronic Thesis and Dissertation Repository
Habitat loss and climate change have caused declines in species diversity and abundance globally, including in butterflies which are important components of many ecosystems. Reintroductions are increasingly used to reverse diversity loss but are most effective when informed using genetics. I developed 24 microsatellites and characterized genetic structure and diversity of the endangered Mottled Duskywing (Erynnis martialis) in Ontario and neighbouring provinces and states. These were used to inform a planned reintroduction in Ontario. Populations had moderate levels of genetic diversity, however all but the largest populations may be subject to appreciable levels of genetic drift. Populations more than 8 ...
Identification Of Dna Methylation Episignatures For Classification And Phenotype/Genotype Correlation In Mendelian Neurodevelopmental Disorders, John Reilly
Electronic Thesis and Dissertation Repository
ABSTRACT: Diagnosis for neurodevelopmental disorders poses numerous challenges, related to the lack of specific findings and limited understanding of clinical impact of the majority of genetic variation. Epigenomics mechanisms involve chemical modifications in DNA that involve a range of cellular mechanisms. DNA methylation is an epigenetic mechanism involving addition and removal of methyl groups to cytosine residues. These methylation signals form episignatures; patterns of methylation that can be used as biomarkers capable of differentiating neurodevelopmental disorders. EpiSigns have enabled molecular diagnosis of a number of genetic conditions, classification of variants of unknown significance, and provided insights into the pathophysiology of ...
From Individuals To Communities: The Effect Of Climate Change On Ectothermic Predators, Matthew Lawrence Meehan
From Individuals To Communities: The Effect Of Climate Change On Ectothermic Predators, Matthew Lawrence Meehan
Electronic Thesis and Dissertation Repository
The living components of ecological systems exist within a nested hierarchy, consisting of individuals, populations, and communities. Because of this nestedness, climate change can greatly impact ecological systems, as whole-organism metabolic and physiological demands change for ectotherms under warming, the effects of which may compound with every succeeding level. Therefore, a multi-level approach can better isolate how climate change will reshape ecological systems. In my doctoral research, I used feeding and mesocosm experiments to examine how climate change affects ectothermic predators at the individual-, population-, and community-level, using mesostigmatic mites (Arachnida: Parasitiformes) as my model predator. My research objectives were ...
Improving Accessibility Of Cancer Research (Canadian Cancer Society - Research Information Outreach Team), Harjot Athwal, Alexander Dimitrov, Ava Kavianpour, Urvi Patel
Improving Accessibility Of Cancer Research (Canadian Cancer Society - Research Information Outreach Team), Harjot Athwal, Alexander Dimitrov, Ava Kavianpour, Urvi Patel
Biochemistry 4455F/G: Translation in Cancer Biology
Cancer is one of the largest human health problems faced globally. Therefore, it is an important focus of research for many disciplines. Cancer research has made significant advancements as clinicians and researchers have expanded their knowledge to better understand this complex disease. Throughout this semester we completed a community engagement learning (CEL) project with the Research Information Outreach Team (RIOT) team from the Canadian Cancer Society (CCS) to promote cancer research amongst adolescents and the general public. We completed blog posts for their website, along with promotional material for their Let’s Talk Cancer (LTC) event and infographics for their ...
Collagen Iv-Β1integrin Regulation Of Exocytotic Machinery In Pancreatic Beta-Cell Insulin Secretion, Malina Barillaro
Collagen Iv-Β1integrin Regulation Of Exocytotic Machinery In Pancreatic Beta-Cell Insulin Secretion, Malina Barillaro
Electronic Thesis and Dissertation Repository
Diabetes is a prevalent metabolic disease characterized by impaired insulin secretion, action, or both. β1-integrin is a key receptor that regulates cell-ECM interactions and is important in maintaining beta-cell functions, including insulin secretion. However, little is reported about the relationship between β1-integrin and the exocytotic proteins involved in insulin secretion. This study examined the influence of ECM-mediated β1-integrin activation on exocytotic machinery involved in insulin secretion using rat insulinoma (INS-1) cells. Collagen IV (COL IV) promoted INS-1 cell adhesion, spreading, and insulin secretion. Additionally, these cells displayed changes in levels and localization of exocytotic proteins involved in insulin secretion. β1-integrin ...
Applications Of Nanopore Dna Sequencing For Improved Genome Assembly, Daniel Giguere
Applications Of Nanopore Dna Sequencing For Improved Genome Assembly, Daniel Giguere
Electronic Thesis and Dissertation Repository
An organism's genome is the ultimate determinant of its functional potential. Understanding genomes is therefore essential to understand function, and a foundational knowledge of a genome is required transfer functions to and from microorganisms of interest. Sequencing DNA using nanopores is a recent advance that resolves limitations of previous technologies, enabling an improved understanding of genomes. For this thesis, I improved our understanding of microbial genomes by developing novel approaches to analyze long read sequencing data, setting the foundation for future synthetic biology work.
Long sequencing reads have enabled routine assembly of complete bacterial genomes by directly sequencing DNA ...
Effects Of Spatial And Temporal Heterogeneity On The Genetic Diversity Of The Alpine Butterfly Parnassius Smintheus, Mel Lucas
Electronic Thesis and Dissertation Repository
Genetic diversity represents a population’s evolutionary potential, as well as its demographic and evolutionary history. Advances in DNA sequencing have allowed the development of new and potentially powerful methods to quantify this diversity. However, when using these methods best practices for sampling populations and analyzing data are still being developed. Furthermore, while effects of the landscape on spatial patterns of genetic variation have received considerable attention, we have a poorer understanding of how genetic diversity changes as a result of temporal variation in environmental and demographic variables. Here, I take advantage of advances in DNA sequencing to investigate genetic ...
Temperature-Dependent Developmental Plasticity In The Cardiorespiratory System Of Atlantic Salmon, Carlie A. Muir
Temperature-Dependent Developmental Plasticity In The Cardiorespiratory System Of Atlantic Salmon, Carlie A. Muir
Electronic Thesis and Dissertation Repository
Anthropogenic climate change is expected to have pervasive impacts on the performance and viability of fishes, as increasing temperatures create aerobically constrained environments for many species. Given the rapid rates of projected temperature increases, it is critical to evaluate the capacity for fish to respond to a changing thermal environment through phenotypic plasticity. In this thesis, I examined the capacity for developmental plasticity in the thermal performance of juvenile Atlantic salmon (Salmo salar) reared under two thermal regimes from fertilization, and investigated potential mechanistic underpinnings within the cardiorespiratory system. Cardiac performance was examined using a noninvasive Doppler echocardiograph system originally ...
Examining The Impact Of Financial Incentive Removal On Physical Activity: A Quasi-Experimental Study Of 584,760 Mobile Health Application Users, Sean Kevin Spilsbury
Examining The Impact Of Financial Incentive Removal On Physical Activity: A Quasi-Experimental Study Of 584,760 Mobile Health Application Users, Sean Kevin Spilsbury
Electronic Thesis and Dissertation Repository
BACKGROUND: Government interest in using financial incentives (FIs) to stimulate physical activity (PA) is increasing. The cost of longer-term incentive interventions may be prohibitive, however. PURPOSE: To examine the impact of FI withdrawal on PA. METHODS: A 25-week retrospective pre-post quasi-experimental study was conducted with users of a FI-based mHealth app. Users from three Canadian provinces were included. Daily FI were removed in Ontario (ON; intervention) but not British Columbia (BC) and Newfoundland and Labrador (NL; control). Simple linear regression models were used to examine weekly mean daily step count after FI withdrawal. RESULTS: The total sample included 584,760 ...
Connexin 43 Contributes To Phenotypic Variability Of The Mouse Skull, Elizabeth Jewlal
Connexin 43 Contributes To Phenotypic Variability Of The Mouse Skull, Elizabeth Jewlal
Electronic Thesis and Dissertation Repository
The purpose of this study was to determine whether connexin 43 (Cx43) contributes to craniofacial phenotypic variability. Skull shape and variation were compared within and among two heterozygous mutant mouse models (G60S/+ and I130T/+) that exhibit different levels of Cx43 channel function when compared to their wildtype counterparts (~80% and ~50% reduction in function, respectively). Results indicated mutants have significant differences in skull shape compared to wildtype littermates. Similar patterns of shape difference were found in both mutants. Increased skull shape variation and a disruption in the covariation of skull structures were observed in G60S/+ mutants only. These results show ...
The Impact Of Energetic Trade-Offs On The Developmental Trajectory And Life History Strategy Of Homo Sapiens: The Modern Human Female Phenotype, Laura Ann Hope Atkinson
The Impact Of Energetic Trade-Offs On The Developmental Trajectory And Life History Strategy Of Homo Sapiens: The Modern Human Female Phenotype, Laura Ann Hope Atkinson
Electronic Thesis and Dissertation Repository
This study interrogates the relationship between early life environmental variability (measured through birth weight and age at menarche), and adult phenotypic outcomes in female athletes and non-athletes from the United Kingdom. Using anthropometric, and 3D body surface scan analysis, patterns of phenotypic variation were interpreted in a life history context. Significant correlations between birth weight, stature, and bi-iliac breadth were observed. Age at menarche had significant correlations with linear growth and body composition measures in both Pearson and Canonical Correlation analyses. Crural index was found to be negatively correlated with limb segment SA:Vol in opposition to the expectations of ...
Spatiotemporal Characterization Of The Prr12 Paralogues In Zebrafish, Renee Jeannine Resendes
Spatiotemporal Characterization Of The Prr12 Paralogues In Zebrafish, Renee Jeannine Resendes
Electronic Thesis and Dissertation Repository
Pathogenic variants in the human PRR12 (Proline Rich 12) gene are associated with PRR12-related Neuroocular Syndrome. However, little is known about the gene/protein function. The zebrafish was utilized to address this, as its attributes place it as a premier model to study genes involved in human development and disease. In situ hybridization and RT-PCR of embryos and larvae, and qRT-PCR of adult tissues revealed the spatial and temporal distributions of the prr12 paralogues: prr12a and prr12b. Both paralogues were detected from the maternal and zygotic transcriptomes in a global and diffuse expression pattern, and there was enrichment of ...
Effects Of Experimental Malaria Infection On Migration Of Yellow-Rumped Warblers (Setophaga Coronata), Rebecca J. Howe
Effects Of Experimental Malaria Infection On Migration Of Yellow-Rumped Warblers (Setophaga Coronata), Rebecca J. Howe
Electronic Thesis and Dissertation Repository
The potential of migratory animals to spread infectious diseases depends on how infection affects movement. If infection delays or slows the speed of travel, transmission to uninfected individuals may be reduced. Whether and how malaria (Plasmodium spp.) affects bird migration has received little experimental research. I captured 40 actively-migrating Yellow-rumped Warblers (Setophaga coronata) at a migration stopover site and held them in captivity. I inoculated 25 with P. cathemerium while 15 received sham inoculations. After 12 days the birds were released. Six P. cathemerium-inoculated birds (24%) developed P. cathemerium infections after inoculation. I radio-tagged all birds, and used radio ...
Mechanisms Of Diapause And Cold Tolerance In The Colorado Potato Beetle, Jacqueline E. Lebenzon
Mechanisms Of Diapause And Cold Tolerance In The Colorado Potato Beetle, Jacqueline E. Lebenzon
Electronic Thesis and Dissertation Repository
Many temperate insects enter diapause (a state of dormancy) and enhance their cold tolerance to survive the winter. During diapause, the Colorado potato beetle (CPB, Leptinotarsa decemlineata, Coleoptera: Chrysomelidae) stops developing, lowers its metabolism, and changes its physiology to avoid freezing. The extent to which diapause confers cold tolerance in CPB is currently unknown. In my thesis, I used CPB to improve our understanding of the mechanisms underlying metabolic suppression during diapause and cellular protection at sub-zero temperatures in insects. First, I used RNA-sequencing (RNA-seq) to compare gene expression in two metabolically important tissues (the fat body and flight muscle ...
The Genetics Of Pain: An Exploration Of Gene-By-Environment Interactions And Their Effects On Pain, Mohamad F. Fakhereddin
The Genetics Of Pain: An Exploration Of Gene-By-Environment Interactions And Their Effects On Pain, Mohamad F. Fakhereddin
Electronic Thesis and Dissertation Repository
The findings presented in this dissertation are part of the bigger SYMBIOME project which aims to use the biopsychosocial model of pain to develop a prognostic clinical phenotype for people that experience musculoskeletal (MSK) trauma. Chapter 2 presents an exploratory analysis to assess the relationships between genetic polymorphisms and pain severity and interference. Early childhood trauma was also explored as a moderator between genetic polymorphisms and pain outcomes. For pain severity, major allele carriers (A/A and G/A) of FKBP5 rs9394314 reported significantly higher scores than minor allele carriers (G/G). Further, major allele carriers who had at least ...
Likely Community Transmission Of Covid-19 Infections Between Neighboring, Persistent Hotspots In Ontario, Canada, Ben C. Shirley, Eliseos J. Mucaki, Peter Rogan
Likely Community Transmission Of Covid-19 Infections Between Neighboring, Persistent Hotspots In Ontario, Canada, Ben C. Shirley, Eliseos J. Mucaki, Peter Rogan
Biochemistry Publications
Introduction: This study aimed to produce community-level geo-spatial mapping of confirmed COVID-19 cases in Ontario Canada in near real-time to support decision-making. This was accomplished by area-to-area geostatistical analysis, space-time integration, and spatial interpolation of COVID-19 positive individuals.
Methods: COVID-19 cases and locations were curated for geostatistical analyses from March 2020 through June 2021, corresponding to the first, second, and third waves of infections. Daily cases were aggregated according to designated forward sortation area (FSA), and postal codes (PC) in municipal regions Hamilton, Kitchener/Waterloo, London, Ottawa, Toronto, and Windsor/Essex county. Hotspots were identified with area-to-area tests including Getis-Ord ...
Using Spatial Methods To Analyse Anthropogenic Predation Risk And Movement Ecology Of White-Tailed Deer (Odocoileus Virginianus), Rhiannon D. Kirton
Using Spatial Methods To Analyse Anthropogenic Predation Risk And Movement Ecology Of White-Tailed Deer (Odocoileus Virginianus), Rhiannon D. Kirton
Electronic Thesis and Dissertation Repository
Hunting has been used as a central tool by wildlife managers to maintain populations of game species, however, we still lack a good understanding of exactly how hunting influences deer biology. Technological advances in GPS data over the last two decades now enable us to perform more detailed analysis on the effects of human hunters on wildlife populations. This research explores the spatial ecology of hunters and White-tailed deer in the Cross Timbers ecoregion of Oklahoma. Using new statistical methodologies to analyse simultaneous GPS tracking data on deer and hunters to study their spatial interactions. The results show how new ...
Investigating Mycelial-Crop Residue Mat Application To Reduce Early-Colonizing Weeds In Row-Crop Agriculture, Donald T. Watson
Investigating Mycelial-Crop Residue Mat Application To Reduce Early-Colonizing Weeds In Row-Crop Agriculture, Donald T. Watson
Electronic Thesis and Dissertation Repository
Herbicide use within conventional agriculture has contributed to greatly increased crop yields since its widespread adoption, but environmental concerns regarding overuse and reliance on selective herbicides continue to mount. Using five fungal species and two crop residues in a factorial design, I created a novel slurry to control weeds through inhibition by the mycelial mat formed after application to soil. I monitored weed stem counts and the strength of the mycelial mat under the treatments. Additionally, as a proxy for crop yield, I measured the wet and dry mass of crop plant grown under application treatments. Weed prevalence was significantly ...
Investigating The Role Of Pkc And Its Mechanisms In Regulation Of Igf-I Bioavailability In Fetal Growth Restriction, Allan W. Chen
Investigating The Role Of Pkc And Its Mechanisms In Regulation Of Igf-I Bioavailability In Fetal Growth Restriction, Allan W. Chen
Electronic Thesis and Dissertation Repository
Fetal growth restriction (FGR) is associated with decreased nutrient availability and reduced insulin-like growth factor (IGF)-I bioavailability via increased IGF binding protein (IGFBP)-1 phosphorylation. While protein kinase C (PKC) is implicated in IGFBP-1 hyperphosphorylation in nutrient deprivation, the mechanisms remain unclear. I hypothesized that the interaction of PKCα with protein kinase CK2β and activation of PKCα under leucine deprivation (L0) mediate fetal hepatic IGFBP-1 hyperphosphorylation. Parallel Reaction Monitoring Mass Spectrometry (PRM-MS) followed by PKCα knockdown demonstrated the PKCα isoform interacts with IGFBP-1 and CK2β under L0. Pharmacological PKCα activation with phorbol 12-myristate 13-acetate (PMA) increased whereas inhibition with ...
Hibernation Is Super Complex: Dynamics Of Electron Transport System Supercomplexes, Amalie J. Hutchinson
Hibernation Is Super Complex: Dynamics Of Electron Transport System Supercomplexes, Amalie J. Hutchinson
Electronic Thesis and Dissertation Repository
The electron transport system complexes form supercomplexes (SCs) within mitochondrial membranes, perhaps increasing respiratory capacity or reducing reactive oxygen species production. My project aimed to determine the abundance, composition, and stability of SCs in a hibernator. Hibernators have dynamic metabolisms that change greatly during the winter. I isolated mitochondria from rats and thirteen-lined ground squirrels (TLGS) in different hibernation states and measured mitochondrial respiration. I extracted mitochondrial proteins using two detergents of different strengths, and quantified SC abundance using 2-dimensional gel electrophoresis and immunoblotting. Rats had fewer SCs than TLGS. SCs are dynamic in hibernation and the complex III composition ...
Exercise As A Treatment For Cognitive Decline In Older Adults: The Role Of Growth Factors And Inflammatory Cytokines, Joshua A. Titus
Exercise As A Treatment For Cognitive Decline In Older Adults: The Role Of Growth Factors And Inflammatory Cytokines, Joshua A. Titus
Electronic Thesis and Dissertation Repository
The purpose of this thesis was to investigate the effects that exercise modalities have on neurotrophic and inflammatory blood markers and cognitive outcomes in older adults. A systematic review and meta-analysis were completed. The included studies illustrated that most of the literature evaluated the effect of aerobic exercise interventions on systemic concentrations of the blood marker brain-derived neurotrophic factor (BDNF). The review found that aerobic exercise increases BDNF and resistance training increases insulin-like growth factor 1 (IGF-1). Interventions with sex-specific cohorts presented advantages in males for blood marker and cognitive outcomes compared to females. One of three included interventions decreased ...
Metabolic Regulation During Extraembryonic Endoderm Differentiation, Mohamed Gatie
Metabolic Regulation During Extraembryonic Endoderm Differentiation, Mohamed Gatie
Electronic Thesis and Dissertation Repository
The inner cell mass undergoes orchestrated cellular divisions resulting in the formation of the epiblast (EPI) and primitive endoderm (PrE). Understanding the process of cell fate specification is crucial to appreciate the intricacies of proper embryonic development. While the mouse embryo is an excellent model, limitations do exist with number, technical challenges, and accessibility, therefore, in my thesis I employed two cell-based models to recapitulate the EPI-PrE fate in vitro. Many signaling pathways have been implicated in this lineage decision, metabolism and its downstream products have been recently regarded as a driver of lineage commitment. Using various biochemical, molecular, and ...
Fear Of Large Carnivores Is Tied To Ungulate Habitat Use: Evidence From A Bifactorial Experiment, Haley K. Epperly, Michael Clinchy, Liana Y. Zanette, Robert A. Mcceery
Fear Of Large Carnivores Is Tied To Ungulate Habitat Use: Evidence From A Bifactorial Experiment, Haley K. Epperly, Michael Clinchy, Liana Y. Zanette, Robert A. Mcceery
Biology Publications
The fear large carnivores inspire in large ungulates has been argued to have cascading effects down food webs. However, a direct link between ungulate habitat use and their fear of large carnivores has not been experimentally tested. To fill this critical gap, we conducted a bi-factorial experiment in an African savanna. We removed shrub cover and broadcast large carnivore vocalizations (leopard, hyena, dog) or non-threatening control vocalizations in both experimentally cleared and shrubby control sites. We recorded the proactive (frequency of visitation) and reactive (fleeing or vigilance) responses of multiple prey (impala, warthog, nyala and bushbuck). Critically, we found a ...
Discovering Body Positivity & Self-Image (Gender Equality Coalition Of Ontario), Ella Clarke, Morolayo Ilori, Melanie Peck, Hannah Polley, Mili Shah
Discovering Body Positivity & Self-Image (Gender Equality Coalition Of Ontario), Ella Clarke, Morolayo Ilori, Melanie Peck, Hannah Polley, Mili Shah
Medical Sciences 4300A: Addressing Healthcare Misconceptions Using Scientific Inquiry
Body image refers to the way we perceive our bodies, and it can positively or negatively impact physical and mental health (Alleva et al., 2015). Unfortunately, negative body image is becoming more common with some studies finding that 65% of young people are dissatisfied with their bodies (Linardon et al., 2021). This can lead to a variety of psychological and behavioral problems and disorders such as body dysmorphia or eating disorders (Alleva et al., 2015). However, many of these consequences associated with negative body image can be circumvented by learning to foster positive body images through building self-esteem (Jessie’s ...
Restructuring Training (Participation House Support Services), Victoria Lun, Do Yeon Oh, Nadir Saeed, Joe Thorne, Alexander Trusler
Restructuring Training (Participation House Support Services), Victoria Lun, Do Yeon Oh, Nadir Saeed, Joe Thorne, Alexander Trusler
Medical Sciences 4300A: Addressing Healthcare Misconceptions Using Scientific Inquiry
Participation House Support Services (PHSS) is a non-profit organization with over 60 locations across Ontario that serves individuals with complex medical, physical, and developmental needs with the goal of including them in the community. The scope of the project covers members of the PHSS organization and the London community that they serve by addressing problems with burnout and culture of resentment that the Coordinators of the organization face. After initial discussions with the community partner, qualitative research was done via focus groups with PHSS Coordinators and training staff. An agreed-upon solution of restructuring the training process was developed, as training ...
A Wicked Problem: The Implementation Of Clinical Guidelines Application To Optimize Patient Care (Uhn Openlab), Ardavan Bonyadi Behrouz, Nelson Chang, Jasmine Luo, Daniel Olteanu, Naomi Smith
A Wicked Problem: The Implementation Of Clinical Guidelines Application To Optimize Patient Care (Uhn Openlab), Ardavan Bonyadi Behrouz, Nelson Chang, Jasmine Luo, Daniel Olteanu, Naomi Smith
Medical Sciences 4300A: Addressing Healthcare Misconceptions Using Scientific Inquiry
The purpose of our partnership with the UHN OpenLab was to discover the barriers involved with automating the sporadic release of clinical practice guidelines (CPGs) into the Innovate Guidelines Application (IGA). The problem is considered wicked—interlocking challenges cannot be addressed by a single solution. Accordingly, the goal was to explore the barriers of stakeholders and specialization groups, general guideline issues, and the considerations of healthcare professionals and public perception. An initial literature review was conducted to discover unidentified problems before a first draft of the systems map was created. Subsequently, connections were formed across problems and each was categorized ...
A Physician’S Guide To Clinical Documentation Improvement: Aligning Cdi To Health Information Practice (Canadian Health Information Management Association), Noor Baldawi, Jacky Cheung, Georgia Diamanakis, Alvina Jiwani, Zexi Wang
A Physician’S Guide To Clinical Documentation Improvement: Aligning Cdi To Health Information Practice (Canadian Health Information Management Association), Noor Baldawi, Jacky Cheung, Georgia Diamanakis, Alvina Jiwani, Zexi Wang
Medical Sciences 4300A: Addressing Healthcare Misconceptions Using Scientific Inquiry
The field of clinical documentation improvement (CDI) is emerging alongside the need for more accurate health care information that is reflective of the health status of Canadians. Health information management professionals and physicians play a critical role in the collection, transformation, protection, and distribution of clinical documentation. The quality of health data is dependent on the physician’s specificity in clinical documentation of patient health records, as this information is converted into data by coding specialists. Coded medical information, and associated hospital data, provides information surrounding patient severity of disease, a hospital’s expected length of stay, and a hospital ...
Supporting Pregnant Persons: The Benefits Of Opening A Birth Centre In London, Ontario (Dynamic Doulas Of London), Alisha George, Megan Harris, Allison Kirkpatrick, Lianna Mathew, Amel Sassi
Supporting Pregnant Persons: The Benefits Of Opening A Birth Centre In London, Ontario (Dynamic Doulas Of London), Alisha George, Megan Harris, Allison Kirkpatrick, Lianna Mathew, Amel Sassi
Medical Sciences 4300A: Addressing Healthcare Misconceptions Using Scientific Inquiry
No abstract provided.
Addressing Workplace Mental Health During Covid-19 (Global Minds Collective), Candace Brooks-Dasilva, Ashlee Jiang, Priya Modi, Komal Patel, Lilian Raphael
Addressing Workplace Mental Health During Covid-19 (Global Minds Collective), Candace Brooks-Dasilva, Ashlee Jiang, Priya Modi, Komal Patel, Lilian Raphael
Medical Sciences 4300A: Addressing Healthcare Misconceptions Using Scientific Inquiry
We aimed to produce novel, comprehensive tools to support The Global MINDS Collective’s mission of co-creating unique workplace infrastructures conducive to employee mental wellness. Our Systems Map uses a multifactorial and intersectional approach to analyze how the COVID-19 pandemic has changed employees’ mental and psychosocial wellness. A systems thinking approach was used to connect ideas from literature and industry resources to expand on concepts such as workplace diversity, burnout, and current practices. The interconnected nature of the systems map allowed us to identify “leverage points,” which were topics with a high degree of connectivity that could be targeted for ...
Alignment Of The United Nations Sustainable Development Goals And The London Plan (Citystudio London), Jack Adams, Trent Arnold, Rachel Jairam, Amani Khan
Alignment Of The United Nations Sustainable Development Goals And The London Plan (Citystudio London), Jack Adams, Trent Arnold, Rachel Jairam, Amani Khan
Medical Sciences 4300A: Addressing Healthcare Misconceptions Using Scientific Inquiry
The goal of our project was to map the City of London Plan to the UN’s Sustainability and Development Goals. An aim of the project was to present the contents in the City of London Plan in a more understandable and accessible way for London citizens and city counsellors to be able to engage with. Another aim was to measure the similarities and discrepancies of the London Plan and the UNs SDGs in a quantifiable way that could be easily examined by the city when creating future city plans. Our deliverables were a 1-minute video pitch, an excel spreadsheet ...