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Smokeless Tobacco Use: A Risk Factor For Hyperhomocysteinemia In A Pakistani Population, Mohammad Perwaiz Iqbal, Mohsin Yakub
Smokeless Tobacco Use: A Risk Factor For Hyperhomocysteinemia In A Pakistani Population, Mohammad Perwaiz Iqbal, Mohsin Yakub
Department of Biological & Biomedical Sciences
Background
Smokeless tobacco (ST) use is highly prevalent in the South Asian populations. While there have been a number of reports on association of ST consumption with cancer, very few studies have been conducted to investigate its relationship with cardiovascular disease. Hyperhomocysteinemia is a well-recognized risk factor for cardiovascular disease; however, its association with ST use has never been investigated. The objective of this study was to evaluate the relationship of ST use with hyperhomocysteinemia in an urban Pakistani population.
Methodology/Principal Findings
In a cross-sectional study for assessment of risks of hyperhomocysteinemia, 872 healthy adults (355 males and 517 females …
Hyperhomocysteinemia And Coronary Artery Disease In Pakistan, M Perwaiz Iqbal
Hyperhomocysteinemia And Coronary Artery Disease In Pakistan, M Perwaiz Iqbal
Department of Biological & Biomedical Sciences
The relative risk of developing coronary artery disease (CAD) in Pakistani men is highest in early ages. Majority of those suffering from CAD belong to the lower middle socioeconomic stratum of the society. Mild hyperhomocysteinemia (concentration of plasma homocysteine between 15-25 micromol/l) is very commonly seen in Pakistani patients with acute myocardial infarction (AMI) as well as in normal healthy subjects. There appears to be a lack of association between hyperhomocysteinemia and CAD in Pakistani population. There is also no evidence of association of methylenetetrahydrofolate reductase 677C>T mutation with CAD in this population. High prevalence of deficiency of folate …
Methylene Tetrahydrofolate Reductase Gene And Coronary Artery Disease, M P. Iqbal, P M. Frossard
Methylene Tetrahydrofolate Reductase Gene And Coronary Artery Disease, M P. Iqbal, P M. Frossard
Department of Biological & Biomedical Sciences
Abstract is not provided by the author/publisher