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Full-Text Articles in Life Sciences

The Potential Role Of Aerobic Exercise-Induced Pentraxin 3 On Obesity-Related Inflammation And Metabolic Dysregulation, Aaron L. Slusher, Chun-Jung Huang, Edmund O. Acevedo Jan 2017

The Potential Role Of Aerobic Exercise-Induced Pentraxin 3 On Obesity-Related Inflammation And Metabolic Dysregulation, Aaron L. Slusher, Chun-Jung Huang, Edmund O. Acevedo

Kinesiology and Health Sciences Publications

Obesity is defined as the excess accumulation of intra-abdominal body fat, resulting in a state of chronic, low-grade proinflammation that can directly contribute to the development of insulin resistance. Pentraxin 3 (PTX3) is an acute-phase protein that is expressed by a variety of tissue and cell sources and provides an anti-inflammatory property to downregulate the production of proinflammatory cytokines, in particular interleukin-1 beta and tumor necrosis factor alpha. Although PTX3 may therapeutically aid in altering the proinflammatory milieu in obese individuals, and despite elevated expression of PTX3 mRNA observed in adipose tissue, the circulating level of PTX3 is reduced with …


A Closer Look At Rural-Urban Health Disparities: Associations Between Obesity And Rurality Vary By Geospatial And Sociodemographic Factors, Steven A. Cohen, Sarah K. Cook, Lauren Kelley, Julia D. Foutz, Trisha A. Sando Jan 2017

A Closer Look At Rural-Urban Health Disparities: Associations Between Obesity And Rurality Vary By Geospatial And Sociodemographic Factors, Steven A. Cohen, Sarah K. Cook, Lauren Kelley, Julia D. Foutz, Trisha A. Sando

Kinesiology and Health Sciences Publications

Background: Obesity affects over one-third of older adults in the United States. Both aging and obesity contribute to an increased risk for chronic disease, early mortality, and additional health care utilization. Obesity rates are higher in rural areas than in urban areas, although findings are mixed. The objectives of this study are to assess potential nonlinearity in the association between rurality and obesity, and to evaluate the potential for socioeconomic status and geographic area to moderate the associations between rurality and obesity.

Methods: Using a representative sample of adults aged 65 and above from the Behavioral Risk Factor Surveillance System, …


Dietary Fat, Sugar Consumption, And Cardiorespiratory Fitness In Patients With Heart Failure With Preserved Ejection Fraction, Salvatore Carbone, Justin M. Canada, Leo F. Buckley, Cory R. Trankle, Hayley E. Billingsley, Dave L. Dixon, Adolfo G. Mauro, Sofanit Dessie, Dinesh Kadariya, Eleonora Mezzaroma, Raffaella Buzzetti, Ross Arena, Benjamin W. Van Tassell, Stefano Toldo, Antonio Abbate Jan 2017

Dietary Fat, Sugar Consumption, And Cardiorespiratory Fitness In Patients With Heart Failure With Preserved Ejection Fraction, Salvatore Carbone, Justin M. Canada, Leo F. Buckley, Cory R. Trankle, Hayley E. Billingsley, Dave L. Dixon, Adolfo G. Mauro, Sofanit Dessie, Dinesh Kadariya, Eleonora Mezzaroma, Raffaella Buzzetti, Ross Arena, Benjamin W. Van Tassell, Stefano Toldo, Antonio Abbate

Kinesiology and Health Sciences Publications

Heart failure with preserved ejection fraction (HFpEF) is associated with obesity and, indirectly, with unhealthy diet. The role of dietary components in HFpEF is, however, largely unknown. In this study, the authors showed that in obese HFpEF patients, consumption of unsaturated fatty acids (UFA), was associated with better cardiorespiratory fitness, and UFA consumption correlated with better diastolic function and with greater fat-free mass. Similarly, mice fed with a high-fat diet rich in UFA and low in sugars had preserved myocardial function and reduced weight gain. Randomized clinical trials increasing dietary UFA consumption and reducing sugar consumption are warranted to confirm …