Life Sciences Commons^™

Comparison Of Downstream Cell Survival Responses In Huvecs And Hlecs During Vegf Signaling, Haley Smith

Seaver College Research And Scholarly Achievement Symposium

Comparison of Downstream Cell Survival Responses in HUVECs and HLECs During VEGF Signaling

Author: Haley M. Smith

Mentor: Thomas L. Vandergon

Angiogenesis and lymphangiogenesis are vital processes that allow the formation of new blood and lymph vessels from existing blood or lymph vessels. Formation of these vessels is essential to bring oxygen and nutrients to the body as well as maintaining tissue fluid balance. New blood or lymph vessel growth occurs in response to Vascular Endothelial Growth Factor (VEGF) signaling to vascular endothelial cells. The VEGF signal molecules bind to cell surface receptors and elicit a variety of responses including …

An Individual-Based Model Of Chaparral Vegetation Response To Frequent Wildfire, Timothy Lucas, Dayna Mann, Reanna Dona

Seaver College Research And Scholarly Achievement Symposium

In recent years, the Santa Monica Mountains (SMM) have been plagued by frequent wildfires which threaten the native chaparral species. Nonsprouting chaparral species are completely killed by a fire, but their seeds germinate in response to fire cues. Facultative sprouters both resprout after a wildfire and release seeds that germinate post-fire. This project is based on data collected since 1986 at a biological preserve adjacent to the Malibu campus of Pepperdine University with an average fire return interval of 7.5 years. We present a spatial model that simulates the growth, seed dispersal and resprouting behavior of individual shrubs that compete …