Rna-Seq Analysis Reveals Distinct Splenic Response Of Two Chickens Lines To Newcastle Disease Virus, Jibin Zhang, Michael G. Kaiser, Melissa S. Herrmann, Rodrigo A. Gallardo, David A. Bunn, Huaijun Zhou, Susan J. Lamont
May 2016
Rna-Seq Analysis Reveals Distinct Splenic Response Of Two Chickens Lines To Newcastle Disease Virus, Jibin Zhang, Michael G. Kaiser, Melissa S. Herrmann, Rodrigo A. Gallardo, David A. Bunn, Huaijun Zhou, Susan J. Lamont
Jibin Zhang
Newcastle disease virus (NDV) is an infectious virus in domestic chickens and is endemic in many countries. It has caused huge economic losses worldwide, especially in developing countries where the chickens and eggs are a primary source of economic income and family nutrition for the rural poor. Due to continuous evolution of NDV and unreliable vaccine production and distribution in developing countries, vaccine cannot prevent recurrent outbreaks of Newcastle disease. Therefore, breeding for NDV resistant chickens is a sustainable approach for alleviating rural poverty and food insecurity.
To identify critical genes regulating NDV resistance, an RNA-seq approach was undertaken with …
Mild Heat Stress Enhances Differentiation And Proliferation Of Japanese Quail Myoblasts And Enhances Slow Muscle Fiber Characteristics, Jibin Zhang, Paula Chen, Kichoon Lee, Seongsoo Hwang, Young Min Choi
Apr 2016
Mild Heat Stress Enhances Differentiation And Proliferation Of Japanese Quail Myoblasts And Enhances Slow Muscle Fiber Characteristics, Jibin Zhang, Paula Chen, Kichoon Lee, Seongsoo Hwang, Young Min Choi
Jibin Zhang
The objective of this study was to investigate the effect of mild heat stress on muscle fiber hyperplastic and hypertrophic growth in quail primary myogenic cells to better understand the mechanisms leading to increased skeletal muscle development in avian embryos incubated at a higher temperature. Compared to control cultures maintained at 37°C, incubation at 39°C enhanced myotube length (P < 0.01) and diameter (P < 0.001) at 3 days after differentiation (D3). This enlargement of the myotubes incubated at 39°C can be explained by differences in the fusion index (56.7 vs. 46.2%, P < 0.05) and nuclei number …
Distinct Cardiac Responses To Heat Stress Between Two Broiler Lines Identified By Transcriptome Analysis, Jibin Zhang, Carl J. Schmidt, Susan J. Lamont
Jan 2016
Distinct Cardiac Responses To Heat Stress Between Two Broiler Lines Identified By Transcriptome Analysis, Jibin Zhang, Carl J. Schmidt, Susan J. Lamont
Jibin Zhang
Prolonged exposure to high temperature can significantly increase metabolism, depress appetite, reduce meat production and raise mortality in broilers. Because the cardiovascular system plays an important role to dissipate heat and transport oxygen, strong cardiac function is indispensable for birds to survive under heat stress. However, due to small hearts relative to body weight, modern broilers have high risk of heart failure at high temperature.
In this study, a Ross 708 line (modern broilers) and a Heritage broiler line (relaxed selection since the 1950s) were subjected to heat stress at 35℃ for 7 hours/day from 21 to 42 days posthatch …
Jibin Zhang's Ppt For Midwest Meeting.Pdf, Jibin Zhang, Yeunsu Suh, Young Min Choi, Michael E. Davis, Kichoon Lee
Mar 2014
Jibin Zhang's Ppt For Midwest Meeting.Pdf, Jibin Zhang, Yeunsu Suh, Young Min Choi, Michael E. Davis, Kichoon Lee
Jibin Zhang
Increasing numbers of fat cells in adipose tissue are attributed to proliferation of preadipocytes or immature adipocytes in the early stages as well as adipogenic differentiation in the later stages of adipogenesis. Although both events are involved in the increase in fat cell numbers, they are contrary to each other in that the former requires cell cycle activity whereas the latter requires cell cycle withdrawal. Therefore, appropriate regulation of cell cycle inhibition is critical to adipogenesis.
To explore the important cell cycle inhibitors and study their expression in adipogenesis, a strategy was adopted that combined the Gene Expression Omnibus (GEO) …
