Life Sciences Commons^™

Propiconazole Is A Specific And Accessible Brassinosteroid (Br) Biosynthesis Inhibitor For Arabidopsis And Maize., Burkhard Schulz, Thomas Hartwig, Claudia Corvalan, Norman Best, Joshua Budka, Sunghwa Choe

Burkhard Schulz

Brassinosteroids (BRs) are steroidal hormones that play pivotal roles during plant development. In addition to the characterization of BR deficient mutants, specific BR biosynthesis inhibitors played an essential role in the elucidation of BR function in plants. However, high costs and limited availability of common BR biosynthetic inhibitors constrain their key advantage as a species-independent tool to investigate BR function. We studied propiconazole (Pcz) as an alternative to the BR inhibitor brassinazole (Brz). Arabidopsis seedlings treated with Pcz phenocopied BR biosynthetic mutants. The steady state mRNA levels of BR, but not gibberellic acid (GA), regulated genes increased proportional to the …