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Transplanting A Bacterial Immune System: Determining The Function Of A Novel Crispr System, Riannon Smith, Melena Garrett
Transplanting A Bacterial Immune System: Determining The Function Of A Novel Crispr System, Riannon Smith, Melena Garrett
Research on Capitol Hill
CRISPR (Clusters of Regularly Interspaced Short Palindromic Repeats) loci and cas (CRISPR-associated) genes provide adaptive immunity (see panel below) in bacteria and have recently been repurposed for genome editing.
Systems are structurally and functionally diverse.
- 2 classes, 6 types, 33 subtypes
- Very few have been studied experimentally
- None of the Type IV systems have been characterized