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Microarray Analysis Of Mrna Translation State In Arabidopsis Thaliana, Bayu Sisay Tiruneh
Microarray Analysis Of Mrna Translation State In Arabidopsis Thaliana, Bayu Sisay Tiruneh
Masters Theses
The synthesis of proteins – translation – is one of the cellular processes that consume a great deal of energy. Genome-wide assays performed in Arabidopsis and other organisms have revealed that the translation status of mRNAs responds dramatically to different stresses and environmental and growth signals. Similar assays have revealed how translation of specific mRNAs is perturbed by genetic mutations in eukaryotic translation initiation factors (eIFs). I performed genome-wide analyses of translation state in A. thaliana seedlings with mutant genotypes for a specific eIF (subunit h of eIF3) and the large ribosomal protein, L24 (RPL24B). Using data from prior microarray …