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Full-Text Articles in Life Sciences
Effect Of 17 Days Of Bed Rest On Peak Isometric Force And Unloaded Shortening Velocity Of Human Soleus Fibers, Jeffrey J. Widrick, Janell Romatowski, James L. W. Bain, Scott W. Trappe, Todd A. Trappe, Joyce L. Thompson, David L. Costill, Danny A. Riley, Robert H. Fitts
Effect Of 17 Days Of Bed Rest On Peak Isometric Force And Unloaded Shortening Velocity Of Human Soleus Fibers, Jeffrey J. Widrick, Janell Romatowski, James L. W. Bain, Scott W. Trappe, Todd A. Trappe, Joyce L. Thompson, David L. Costill, Danny A. Riley, Robert H. Fitts
Biological Sciences Faculty Research and Publications
The purpose of this study was to examine the effect of prolonged bed rest (BR) on the peak isometric force (Po) and unloaded shortening velocity (Vo) of single Ca2+-activated muscle fibers. Soleus muscle biopsies were obtained from eight adult males before and after 17 days of 6° head-down BR. Chemically permeabilized single fiber segments were mounted between a force transducer and position motor, activated with saturating levels of Ca2+, and subjected to slack length steps. Vo was determined by plotting the time for force redevelopment vs. the slack step distance. …