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Full-Text Articles in Life Sciences

Social Sciences, Not Given Dec 2014

Social Sciences, Not Given

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Lkb1 Deficient Non-Small Cell Lung Cancer Cells Are Vulnerable To Energy Stress Induced By Atp Depletion, Chao Yang Dec 2014

Lkb1 Deficient Non-Small Cell Lung Cancer Cells Are Vulnerable To Energy Stress Induced By Atp Depletion, Chao Yang

UT GSBS Dissertations and Theses (Open Access)

Lung cancer is the second most frequent cancer in United States, which represents about 13.5% of new cancer cases every year. It accounts for about 27.2% of all cancer related deaths, which is more than the sum of deaths caused by prancretic, breast and colorectal. On average, only about 16% of lung cancer patients survive beyond 5 years. LKB1 is the third most mutated gene in lung cancer. It has been shown that LKB1 is mutated in at least 15% to 30% of NSCLC. Tumor with LKB1 mutation is associated with poor differentiation, high metastasis and worse response ...


Swarna Ramaswamy_Thesis, Swarna S. Ramaswamy Dec 2014

Swarna Ramaswamy_Thesis, Swarna S. Ramaswamy

UT GSBS Dissertations and Theses (Open Access)

STRUCTURAL INVESTIGATIONS OF LIGAND GATED ION CHANNELS

Swarna Ramaswamy, B.S

Advisor: Vasanthi Jayaraman, Ph.D.

Ion channels form an integral part of membrane proteins. In the nervous system including the central and the peripheral nervous system, ligand gated ion channels form a very important part of intercellular communications. They receive chemical signals and convert them to electrical signal, mainly by allowing ion passage across the cell membrane. Ion passage also translates into downstream signaling events. Faithful translation of these signals and transmittance is crucial for several physiological functions, implying that irregular ion channel function could lead to serious consequences ...


An Analysis Of Mayo Clinic Search Query Logs For Cardiovascular Diseases, Ashutosh Sopan Jadhav, Amit P. Sheth, Jyotishman Pathak Nov 2014

An Analysis Of Mayo Clinic Search Query Logs For Cardiovascular Diseases, Ashutosh Sopan Jadhav, Amit P. Sheth, Jyotishman Pathak

Kno.e.sis Publications

Increasingly, individuals are taking active participation in learning and managing their health by leveraging online resources. Understanding online health information searching behavior can help us to study what health topics users search for and how search queries are formulated. In this work, we analyzed 10 million cardiovascular diseases (CVD) related search queries from MayoClinic.com. We performed semantic analysis on the queries using UMLS MetaMap and analyzed structural and textual properties as well as linguistic characteristics of the queries.


Online Information Searching For Cardiovascular Diseases: An Analysis Of Mayo Clinic Search Query Logs, Ashutosh Sopan Jadhav, Amit P. Sheth, Jyotishman Pathak Nov 2014

Online Information Searching For Cardiovascular Diseases: An Analysis Of Mayo Clinic Search Query Logs, Ashutosh Sopan Jadhav, Amit P. Sheth, Jyotishman Pathak

Kno.e.sis Publications

Since the early 2000’s, Internet usage for health information searching has increased significantly. Studying search queries can help us to understand users “information need” and how do they formulate search queries (“expression of information need”). Although cardiovascular diseases (CVD) affect a large percentage of the population, few studies have investigated how and what users search for CVD. We address this knowledge gap in the community by analyzing a large corpus of 10 million CVD related search queries from MayoClinic.com. Using UMLS MetaMap and UMLS semantic types/concepts, we developed a rule-based approach to categorize the queries into 14 ...


Hundreds Of Scn-Resistant Soybean Varieties Available For 2014, Gregory L. Tylka Oct 2014

Hundreds Of Scn-Resistant Soybean Varieties Available For 2014, Gregory L. Tylka

Integrated Crop Management News

The soybean cyst nematode (SCN) is a serious yield-reducing pathogen of soybeans. It is present in many fields throughout the Midwest, wherever soybeans are grown.

To produce profitable soybean yields in fields infested with SCN, farmers should grow SCN-resistant soybean varieties. SCN-resistant soybeans can produce high yields while keeping SCN population densities from increasing.


Social Immunity And The Expression Of Immune-Related Genes In The Eastern Subterranean Termite, Qi Gao Oct 2014

Social Immunity And The Expression Of Immune-Related Genes In The Eastern Subterranean Termite, Qi Gao

University of Western Ontario - Electronic Thesis and Dissertation Repository

Individuals living within social groups may benefit from the efficiencies of division of labour, but on the other hand render themselves vulnerable to socially transmitted disease. This cost to social living should promote cooperative barriers to disease transmission, especially in eusocial taxa where spatial and genetic proximity to nestmates are characteristically pronounced. Though studies of the immunity at multiple levels in social species are becoming more common, little is known about how their sociality is deployed to resist contagion. By exposing the Eastern subterranean termite Reticulitermes flavipes to entomopathogenic fungi, I studied their immune responses at multiple levels. At the ...


Characterization Of The Transcriptome, Nucleotide Sequence Polymorphism, And Natural Selection In The Desert Adapted Mouse Peromyscus Eremicus, Matthew D. Macmanes, Michael B. Eisen Oct 2014

Characterization Of The Transcriptome, Nucleotide Sequence Polymorphism, And Natural Selection In The Desert Adapted Mouse Peromyscus Eremicus, Matthew D. Macmanes, Michael B. Eisen

Molecular, Cellular and Biomedical Sciences Scholarship

As a direct result of intense heat and aridity, deserts are thought to be among the most harsh of environments, particularly for their mammalian inhabitants. Given that osmoregulation can be challenging for these animals, with failure resulting in death, strong selection should be observed on genes related to the maintenance of water and solute balance. One such animal, Peromyscus eremicus, is native to the desert regions of the southwest United States and may live its entire life without oral fluid intake. As a first step toward understanding the genetics that underlie this phenotype, we present a characterization of the P ...


Jackson Lake Limnology, Wayne Wurtsbaugh Oct 2014

Jackson Lake Limnology, Wayne Wurtsbaugh

Watershed Sciences Faculty Publications

The limnology of Jackson Lake has been studied very little, despite the fact that it is the uppermost large lake on the headwaters of the Snake River, one of the larger rivers in the country (Hayden 1969). It is also an important fishery, largely for introduced lake trout. In 2014 we took our incoming graduate students to the Jackson Hole and one part of this introductory course focused on the limnology of the lake. Prior to the arrival of the students, a nutrient addition bioassay was initiated to demonstrate an experimental approach to understanding what nutrients might control production processes ...


Hla Class Ii Alleles In The Otomi Population Of The Mezquital Valley. A Genetic Approach To The History Of Interethnic Migrations In The Mexican Central Plateau, Ana Itzel Juárez-Martín, Blanca Zoila González-Sobrino, Ángel Eduardo Camarena Olvera, Ramcés Falfán-Valencia Oct 2014

Hla Class Ii Alleles In The Otomi Population Of The Mezquital Valley. A Genetic Approach To The History Of Interethnic Migrations In The Mexican Central Plateau, Ana Itzel Juárez-Martín, Blanca Zoila González-Sobrino, Ángel Eduardo Camarena Olvera, Ramcés Falfán-Valencia

Human Biology Open Access Pre-Prints

From a historic and genetic point of view, the Otomi of the Mezquital Valley are a frontier people that have played an important role in the making of the population dynamics of the Mexican Central Plateau. Due to their antiquity in the area, the Otomi may be bearers of ancient genetic variability, shared mainly today with other groups belonging to the Otomanguean linguistic family and with the Nahua.

This study analyzes the HLA class II allele frequencies reported in Mexican indigenous populations, in order to provide an intra-regional level historical perspective of the genetic relationships between the Otomi of the ...


Documentation Of The Black-Footed Ferret, Mustela Nigripes On The Standing Rock Indian Reservation, Mobridge, South Dakota, Michael P. Gutzmer, Jeffrey C. Kelly Oct 2014

Documentation Of The Black-Footed Ferret, Mustela Nigripes On The Standing Rock Indian Reservation, Mobridge, South Dakota, Michael P. Gutzmer, Jeffrey C. Kelly

Transactions of the Nebraska Academy of Sciences and Affiliated Societies

Since 1991, 19 specific black-footed ferret reintroduction projects have been conducted across 8 States, Canada, and Mexico. All five of the first ferret reintroductions (from 1991 to 1996) continue to be occupied by ferrets. The photographs of October 31 and November 1 are the first unequivocal documentation of black-footed ferrets on the Standing Rock Indian Reservation. Ferrets observed on Standing Rock may be dispersals from the nearby Cheyenne River Sioux Indian Reservation to the south. The nearest re-introduction site for ferrets is approximately 20 miles away, in Whitehorse, South Dakota, and the observation of ferrets on Standing Rock could document ...


Ranch-Level Economic Impacts Of Altering Grazing Policies On Federal Land To Protect The Greater Sage-Grouse, John A. Tanaka, Neil R. Rimbey, L. Allen Torell Oct 2014

Ranch-Level Economic Impacts Of Altering Grazing Policies On Federal Land To Protect The Greater Sage-Grouse, John A. Tanaka, Neil R. Rimbey, L. Allen Torell

John A Tanaka

No abstract provided.


The Figure Of Bitu-Man, Paul Royster Oct 2014

The Figure Of Bitu-Man, Paul Royster

Faculty Publications, UNL Libraries

The ominously imposing figure in the above illustration is “the Syncrude bird deterrent device, locally known as ‘Bitu-man’.” He stands (or stood—the original image was from the late 1970s) in the tailings pond of the Syncrude Canada Ltd. oil sands mining operation along the Athabasca River near Fort McMurray in northeastern Alberta. That operation surface mines (i.e., strip mines) bitumen-impregnated sand, processes it with hot water and steam, and discharges the liquid effluent or “tailings” into a pond covering roughly 3000 hectares (11 square miles). (Google Map coordinates: 56.9°N, -111.3° W). Residue bitumen collects on ...


The Status Of Fishes In The Missouri River, Nebraska: Lake Sturgeon (Acipenser Fulvescens), Kirk D. Steffensen, Sam Stukel, Dane A. Shuman Oct 2014

The Status Of Fishes In The Missouri River, Nebraska: Lake Sturgeon (Acipenser Fulvescens), Kirk D. Steffensen, Sam Stukel, Dane A. Shuman

Transactions of the Nebraska Academy of Sciences and Affiliated Societies

Lake Sturgeon (Acipenser fulvescens) occurrences in the Missouri River along Nebraska’s eastern border are historically sporadic and rare. Presently, the wild Lake Sturgeon population in this river reach may be extirpated. A Recovery Program initiated by the Missouri Department of Conservation (MDC) has stocked almost 150,000 hatchery-reared Lake Sturgeon into the lower Missouri River at several sites in Missouri. As a result, the number of Lake Sturgeon collected has increased. Since monitoring began in 2003, no Lake Sturgeon have been collected above Gavins Point Dam while 40 fish were collected downstream of Gavins Point Dam. The majority of ...


Effect Of Plasticizer On Oxygen Permeability Of Cast Polylactic Acid (Pla) Films Determined Using Dynamic Accumulation Method, Kurniawan Yuniarto, Bruce A. Welt, Aris Purwanto, Hadi Karia Purwadaria, Ayman Abdellatief, Titi C. Sunarti, Setyo Purwanto Oct 2014

Effect Of Plasticizer On Oxygen Permeability Of Cast Polylactic Acid (Pla) Films Determined Using Dynamic Accumulation Method, Kurniawan Yuniarto, Bruce A. Welt, Aris Purwanto, Hadi Karia Purwadaria, Ayman Abdellatief, Titi C. Sunarti, Setyo Purwanto

Journal of Applied Packaging Research

Polylactic acid (PLA) is becoming an increasingly important biopolymer for packaging applications. PLA brittleness limits its applicability. This study evaluated PLA properties with increasing amounts of added polyethylene glycol (PEG) plasticizer. Oxygen transmission rate (OTR) of cast films was determined using the newly available Dynamic Accumulation (DA) method. Arrhenius temperature sensitivity of OTR and polymer Permeability was also determined. Permeability of neat PLA is 4.848 ml mm (STP)/m2 s kPa; hence, 4.84 ml mm (STP)/m2 s kPa, 4.07 ml mm (STP)/m2 s kPa and 5.42 ml mm (STP)/m2 ...


South Loup River Valley Floristics: A Survey Of Selected Sites In Buffalo County, Nebraska, Steven J. Rothenberger, April M. Christman, Kevin Turek, Emmylou A. O'Brien Oct 2014

South Loup River Valley Floristics: A Survey Of Selected Sites In Buffalo County, Nebraska, Steven J. Rothenberger, April M. Christman, Kevin Turek, Emmylou A. O'Brien

Transactions of the Nebraska Academy of Sciences and Affiliated Societies

Originating in the Nebraska Sand Hills, the South Loup River flows 30 km north of Kearney, Nebraska and traverses the northern edge of Buffalo County as it flows eastward to its confluence with the Middle Loup River in southwestern Howard County. Several diverse plant communities are associated with the South Loup Valley, including wet-meadows, wetland/oxbows, sand prairie, and riparian forest. Over a period of 6 years (2006-2012), we surveyed representative wet meadow, wetland, and sand prairie communities. We compiled an annotated vascular plant checklist that included 324 vascular plant species of which 11 were new county records. Three species ...


Conesus Lake Fish Stock Assessments 2001-2009, Matthew J. Sanderson Oct 2014

Conesus Lake Fish Stock Assessments 2001-2009, Matthew J. Sanderson

Government Documents

Warm water fisheries assessments using standard gangs of gill nets were conducted in Conesus Lake in September of 2001, 2004, and 2009. The purpose of the surveys was to assess the fish community; the contribution of stocked fingerlings to the walleye (Sander vitreus) population; estimate population characteristics of walleye, smallmouth bass (Micropterus dolomieui), and northern pike (Esox lucius); compare fish community structure to previous surveys; and guide the development of appropriate management recommendations. From the 1990’s to the 2000’s, species dominance shifted from walleye to sunfish (Lepomis, sp.), and yellow perch (Perca flavescens) went from being a major ...


Tattletales And T-Bow Update 20141018, George Mcnamara Oct 2014

Tattletales And T-Bow Update 20141018, George Mcnamara

George McNamara

Tattletales and T-Bow Update 20141018

http://works.bepress.com/gmcnamara/63

Tattletales is my concept to multiplex fluorescent protein biosensors ("Tattletales", which is also the overall concept name) and multicolor FP reporters ("T-Bow" for Rainbow T-cells and tumor cells) to study the physiology of live cells.

These are based on:

1. LacI-GFP :: LacO operator synthetic tandem repeat array (Robinett et al 1996 JCB, Fig 4A, http://jcb.rupress.org/content/135/6/1685.full.pdf )

2. the plethora of fluorescent protein biosensors - see page 1 of this "63" download site.

3. the many colors, and combinations of colors (CY11.5 ...


Lead Exposure From Aluminum Cookware In Cameroon, Jeffrey D. Weidenhamer, Peter A. Lobunski, Gilbert Kuepouo, Rebecca W. Corbin, Perry Gottesfeld Oct 2014

Lead Exposure From Aluminum Cookware In Cameroon, Jeffrey D. Weidenhamer, Peter A. Lobunski, Gilbert Kuepouo, Rebecca W. Corbin, Perry Gottesfeld

Jeffrey D. Weidenhamer

Blood lead levels have decreased following the removal of lead from gasoline in most of the world. However, numerous recent studies provide evidence that elevated blood lead levels persist in many low and middle-income countries around the world at much higher prevalence than in the more developed countries. One potential source of lead exposure that has not been widely investigated is the leaching of lead from artisanal aluminum cookware, which is commonly used in the developing world. Twenty-nine samples of aluminum cookware and utensils manufactured by local artisans in Cameroon were collected and analyzed for their potential to release lead ...


Intercollegiate Cross Country Competition: Effects Of Warm-Up And Racing On Salivary Levels Of Cortisol And Testosterone, Kathleen V. Casto, Christopher Elliott, David A. Edwards Oct 2014

Intercollegiate Cross Country Competition: Effects Of Warm-Up And Racing On Salivary Levels Of Cortisol And Testosterone, Kathleen V. Casto, Christopher Elliott, David A. Edwards

International Journal of Exercise Science

International Journal of Exercise Science 7(4) : 318-328, 2014. Team intercollegiate athletic competition is associated with an increase in salivary cortisol (C) and testosterone (T) in men and women. The present study was designed to determine the hormonal effects of warm-up and racing in cross country runners – a sport that has both individual and team components. Members of the Emory University men’s and women’s varsity cross country teams gave saliva samples before warm-up, after warm-up, and immediately after the finish of each of two intercollegiate invitational meets held one year apart in the same setting (2010, N = 10 ...


Vo2 Reserve Vs. Heart Rate Reserve During Moderate Intensity Treadmill Exercise, Tanner J. Solheim, Brad G. Keller, Charles J. Fountaine Oct 2014

Vo2 Reserve Vs. Heart Rate Reserve During Moderate Intensity Treadmill Exercise, Tanner J. Solheim, Brad G. Keller, Charles J. Fountaine

International Journal of Exercise Science

International Journal of Exercise Science 7(4) : 311-317, 2014. ­VO2 and heart rate (HR) are widely used when determining appropriate training intensities for clinical, healthy, and athletic populations. It has been shown that if the % reserve (%R) is used, rather than % of max, HR and VO2 can be used interchangeably to accurately prescribe exercise intensities. Thus, heart rate reserve (HRR) can be prescribed if VO2 reserve (VO2R) is known. Therefore, the purpose of this study was to compare VO2 R and HRR during moderate intensity exercise (50%R). Physically active college students performed a ...


Muscle Activity In Single- Vs. Double-Leg Squats, Bradley A. Deforest, Gregory S. Cantrell, Brian K. Schilling Oct 2014

Muscle Activity In Single- Vs. Double-Leg Squats, Bradley A. Deforest, Gregory S. Cantrell, Brian K. Schilling

International Journal of Exercise Science

International Journal of Exercise Science 7(4) : 302-310, 2014. Muscular activity, vertical displacement and ground reaction forces of back squats (BS), rear-leg elevated split squats (RLESS) and split squats (SS) were examined. Nine resistance-trained men reported for two sessions. The first session consisted of the consent process, practice, and BS 1-repetition maximum testing. In the second session, participants performed the three exercises while EMG, displacment and ground reaction force data (one leg on plate) were collected. EMG data were collected from the gluteus maximus (GMX), biceps femoris (BF), semitendinosus (ST), rectus femoris (RF), vastus lateralis (VL), vastus medialis (VM), tibialis ...


Occupational Sitting And Physical Activity Among University Employees, Charles J. Fountaine, Meredith Piacentini, Gary A. Liguori Oct 2014

Occupational Sitting And Physical Activity Among University Employees, Charles J. Fountaine, Meredith Piacentini, Gary A. Liguori

International Journal of Exercise Science

International Journal of Exercise Science 7(4) : 295-301, 2014. The prevalence of overweight and obese in the U.S. has been thoroughly documented. With the advent of inactivity physiology research and the subsequent interest in sedentary behavior, the work environment has come under closer scrutiny as a potential opportunity to reverse inactivity. Therefore, the purpose of this study was to determine the sitting and physical activity (PA) habits among different classifications of university employees. University employees (n=625) completed an online survey based on the Occupational Sitting and Physical Activity Questionnaire (OSPAQ). Participants were instructed to describe time spent sitting ...


Time Spent In Mvpa During Exergaming With Xbox Kinect In Sedentary College Students, Chie Yang, Zachary Wickert, Samantha Roedel, Alexandria Berg, Alex Rothbauer, Marquell Johnson, Donald Bredle Oct 2014

Time Spent In Mvpa During Exergaming With Xbox Kinect In Sedentary College Students, Chie Yang, Zachary Wickert, Samantha Roedel, Alexandria Berg, Alex Rothbauer, Marquell Johnson, Donald Bredle

International Journal of Exercise Science

International Journal of Exercise Science 7(4) : 286-294, 2014. The primary purpose of this study was to determine the amount of time spent in moderate-to-vigorous physical activity (MVPA) during a 30-minute bout of exergaming with the Xbox Kinect game console in sedentary college-aged students. A secondary purpose was to examine enjoyment level of participation in the selected exergame. Twenty college-aged students (14 females and 6 males) who self-reported being physically inactive and having no prior experience with the Xbox Kinect game “Your Shape Fitness Evolved 2012” Break a Sweat activity participated in the study. Participants came into the lab on ...


Can Resistance Training Contribute To The Aerobic Components Of The Physical Activity Guidelines?, Travis J. Hrubeniuk, Neal Prokop, Semone Myrie, Martin Sénéchal, Danielle R. Bouchard Oct 2014

Can Resistance Training Contribute To The Aerobic Components Of The Physical Activity Guidelines?, Travis J. Hrubeniuk, Neal Prokop, Semone Myrie, Martin Sénéchal, Danielle R. Bouchard

International Journal of Exercise Science

International Journal of Exercise Science 7(4) : 278-285, 2014. To evaluate if resistance training can reach Moderate to Vigorous Intensity (MVI) and contribute to the aerobic component of the international physical activity guidelines. Sixteen participants aged between 20 and 35 were recruited. Heart rate was recorded by heart rate monitor during a resistance training program. Based on maximal heart rate, time spent at MVI (55-69% of maximal heart rate) was calculated. Participants displayed a HR equal or above MVI for 51.5% ± 21.7% of time. When stratifying by lower and upper body sessions, that proportion was median (25-75th); 75 ...


The Acute Effects Of A Dynamic Stretching Protocol On Wingate Performance, Autumn S. Gipson Ms., Jamarious Jones, Elise N. Ritchey, Colby Murphy, Hope Grimes, John M. Coons Oct 2014

The Acute Effects Of A Dynamic Stretching Protocol On Wingate Performance, Autumn S. Gipson Ms., Jamarious Jones, Elise N. Ritchey, Colby Murphy, Hope Grimes, John M. Coons

International Journal of Exercise Science

International Journal of Exercise Science 7(4) : 271-277, 2014. Stretching before performing anaerobic activity has been a highly debated subject, with studies finding differing results depending on the type (static, dynamic, etc.) and duration of the stretch. Furthermore, the effects of dynamic stretching (DS) on anaerobic performance have been minimally researched. The purpose of this study was to examine the effects a DS protocol had on power performance using a Wingate test (WAnT). College-aged male subjects were recruited for this study. Prior to experimental trials, subjects performed a familiarity WAnT trial. Subjects then performed the WAnT two more times, once ...


The Relationship Between Change Of Direction Speed In The Frontal Plane, Power, Reactive Strength, And Strength, Brian T. Mccormick, James C. Hannon, Charlie A. Hicks-Little, Maria Newton, Barry Shultz, Nicole Detling, Warren B. Young Oct 2014

The Relationship Between Change Of Direction Speed In The Frontal Plane, Power, Reactive Strength, And Strength, Brian T. Mccormick, James C. Hannon, Charlie A. Hicks-Little, Maria Newton, Barry Shultz, Nicole Detling, Warren B. Young

International Journal of Exercise Science

International Journal of Exercise Science 7(4) : 260-270, 2014. Change-of-direction speed (CODS) is an important quality to performance in multi-direction sports. The relationship between CODS in the frontal plane and power, strength, and reactive strength is largely unstudied. Twenty-three male college students participated in this study. The study used a Pearson’s product-moment correlation to measure the relationship between CODS, power, strength, and reactive strength. A lateral shuffle test was used as the measure of CODS. A lateral hop for distance was used as the measure of power in the frontal plane. A countermovement vertical jump test was used as ...


Perguson, Dee Carl, 1921-2010 (Sc 2861), Manuscripts & Folklife Archives Oct 2014

Perguson, Dee Carl, 1921-2010 (Sc 2861), Manuscripts & Folklife Archives

MSS Finding Aids

Finding aid only for Manuscripts Small Collection 2861. Letters of Ohio County, Kentucky native Dee Carl Perguson, written to Marjorie Clagett, his French teacher at Western Kentucky State Teachers College, during his World War II military service and afterward. He writes observantly of military life while training in Ohio, Georgia and Pennsylvania, of his experiences while serving in North Africa and Italy, and of his reassignment to Florida after suffering an arm wound. He also describes local plant life to Clagett, an accomplished amateur botanist. After the war, he writes from England during his postgraduate study. Settled in Seattle, Washington ...


Ligand-Directed Signaling And Trafficking At The Nociceptin Opioid Peptide Receptor, Gina E. Migneco Oct 2014

Ligand-Directed Signaling And Trafficking At The Nociceptin Opioid Peptide Receptor, Gina E. Migneco

Undergraduate Research Symposium Posters & Abstracts

Traditional opioid receptors such as the μ and κ opioid receptors (MOR and

KOR) are well studied and are found to be common targets for pain and

stress therapies. The nociceptin opioid receptor (NOPR/ORL1) is a most

recently discovered opioid receptor whose complete function is still relatively

unknown, however is of great interest to researchers due to its analgesic

and antidepressant properties. NOPR activation due to ligand binding

triggers a variety of downstream effects, including G-protein signaling,

arrestin-mediated signaling, and receptor internalization. A variety of NOPR

ligands, both putative agonists and antagonists, were characterized by

further examination of these ...


Citrus Notes-Agricultural Advantages Of So. California, Charles C. Chapman Oct 2014

Citrus Notes-Agricultural Advantages Of So. California, Charles C. Chapman

Charles C. Chapman Citrus Speeches

These are notes from a speech given by Mr. Chapman at a banquet at the Pomona Farmer's Club Institute. He details the environmental advantages that Southern California has in relation to the rest of the world.