Life Sciences Commons^™

Recent Decline Of Lowland Populations Of The Western Gray Squirrel In The Los Angeles Area Of Southern California, Daniel S. Cooper, Alan Muchlinski

Bulletin of the Southern California Academy of Sciences

We provide an overview of the distribution of lowland and otherwise isolated populations of the western gray squirrel (Sciurus griseus) in the Los Angeles area of southern California, an area that has experienced a recent and ongoing invasion by the non-native eastern fox squirrel (Sciurus niger), an urban-adapted species introduced a century ago. Away from its strongholds in the western Santa Monica Mountains, San Gabriel Mountains, and Santa Ana Mountains, the western gray squirrel is resident locally in both the Santa Susana and the Verdugo Mountains, in Griffith Park, in low hills at the eastern periphery of the San Gabriel ...

An Orange Fluorescent Protein Tagging System For Real-Time Pollen Tracking, J. Rice, R. Mundell, R. Millwood, O. Chambers, L. Abercrombie, H. Davies, C. Stewart

C. Neal Stewart Jr.

Background Monitoring gene flow could be important for future transgenic crops, such as those producing plant-made-pharmaceuticals (PMPs) in open field production. A Nicotiana hybrid (Nicotiana. tabacum × Nicotiana glauca) shows limited male fertility and could be used as a bioconfined PMP platform. Effective assessment of gene flow from these plants is augmented with methods that utilize fluorescent proteins for transgenic pollen identification. Results We report the generation of a pollen tagging system utilizing an orange fluorescent protein to monitor pollen flow and as a visual assessment of transgene zygosity of the parent plant. This system was created to generate a tagged ...

Effect Of External Energy On The Atomic, Crystalline, And Powder Characteristics Of Antimony And Bismuth Powders, Mahendra Kumar Trivedi

Mahendra Kumar Trivedi

Next to atoms and molecules the powders are the smallest state of matter available in high purities and large quantities. The effect of any external energy on the shape, morphology and structure can thus be studied with relative ease. The present investigation deals with the effect of a non-contact external energy on the powders of antimony and bismuth. The characteristics of powders treated by external energy are compared with the as received powders (control). The average particle sizes, d50 and d99, the sizes below which 99% of the particles are present showed significant increase and decrease indicating that the energy ...

Titus Thesis Figures.Docx, Titus Hou

Titus Hou

No abstract provided.

Titus Thesis.Docx, Titus Hou

Titus Hou

No abstract provided.

Effects Of Slope Upon Hind Limb Kinematics In Chukar Partridge (Alectoris Chukar), Anna T. Kenney

Undergraduate Theses and Professional Papers

Ground dwelling birds must scale all kinds of complex terrain in order to survive in their natural environments. For instance, Alectoris chukar live on steep hillsides with slopes of up to 60° or 172.3% slope. We undertook the present study to improve understanding of how birds successfully traverse such complex terrain. Using a high speed camera, we analyzed the hind limb kinematics of chukars during normal locomotion on a 10° and 35° incline, decline, and level slope. We compared the data collected from the video recordings, which we had used to identify and digitize the bony landmarks, between all ...

Máy Lọc Nước Điện Giải Kangen Leveluk K8 Nhật Bản Chính Hãng, Nhung Seven

Nhung Seven

Real-Time Stealth Intervention For Motor Learning Using Player Flow-State, Ramin Tadayon, Ashish Amresh, Troy Mcdaniel, Sethuraman Panchanathan

Ashish Amresh

Messy Eating, Samantha King, R Scott Carey, Isabel Macquarie, Victoria Millious, Elaine Power

Environmental Studies

Literature on the ethics and politics of food and that on animal-human relationships have infrequently converged. Representing an initial step towards bridging this divide, Messy Eating features interviews with thirteen prominent and emerging scholars about the connections between their academic work and their approach to consuming animals as food. The collection explores how authors working across a range of perspectives—postcolonial, Indigenous, Black, queer, trans, feminist, disability, poststructuralist, posthumanist, and multispecies—weave their theoretical and political orientations with daily, intimate, and visceral practices of food consumption, preparation, and ingestion.

Contributors: Neel Ahuja, Billy Ray Belcourt, Matthew Calarco, Lauren Corman, Naisargi ...

Effect Of Turmeric On The Promoter Activity Of The Cyp6a8 Gene Of Drosophila Melanogaster, Alexa Stroh

University of Tennessee Honors Thesis Projects

No abstract provided.

Untangling The Economic And Social Impediments To Producer Adoption Of Organic Wheat, Donya L. Ralph-Quarnstrom

All Graduate Theses and Dissertations

Consumer demand for organic products has shown double-digit growth in recent years encouraging the development of a wider range of goods (Greene, 2017). Americans with an annual household income under $30,000 actively purchase organic foods at nearly the same rate as households with over $75,000 in annual incomes, 42% versus 49% (Greene et al., 2017). Previous research observed the adoption of organic farming practices on a combination of different grains, fruits and vegetables, meat, and dairy products from across the globe. However, this is the first study to examine the adoption of organic wheat in the Western U ...

Impacts Of Cattle Grazing As A Tool To Control Phragmites Australis In Wetlands On Nitrogen, Phosphorus, And Carbon, Brittany L. Duncan

All Graduate Theses and Dissertations

Phragmites australis is a plant that is causing problems in wetlands by outcompeting native plants that provide food and shelter for millions of migratory birds. Currently, managers try to control Phragmites australis by spraying herbicide, burning, and mowing, but these methods are costly, time consuming, and have low levels of success. Adding grazing as a tool to control Phragmites australis provides a cheap and low labor alternative. However, there are many concerns regarding if grazing will cause nutrient loading in our wetlands that will decrease water quality and alter beneficial functions of wetlands.

To better understand the effects of grazing ...

Reoccupy Earth [Table Of Contents], David Wood

Philosophy

Habit rules our lives. And yet climate change and the catastrophic future it portends, makes it clear that we cannot go on like this.

Our habits are integral to narratives of the good life, to social norms and expectations, as well as to economic reality. Such shared shapes are vital. Yet while many of our individual habits seem perfectly reasonable, when aggregated together they spell disaster. Beyond consumerism, other forms of life and patterns of dwelling are clearly possible. But how can we get there from here?

Philosophy is about emancipation—from illusions, myths, and oppression. In Reoccupy Earth, the ...

Exterranean [Table Of Contents], Phillip John Usher

Literature

“For anyone who might be suffering from Anthropocene fatigue, this is a book to jolt you from your slumbers. What happens to the globe when we shift attention from the outward projection of emissions to extraction ? The Earth we thought we knew, and were already mourning, takes on a stunning new critical light.”—Claire Colebrook, Pennsylvania State University

Exterranean concerns the extraction of stuff from the Earth, a process in which matter goes from being sub- to exterranean. By bringing a rich archive of nonmodern texts and images from across Europe, into conversation with the contemporary work of Bruno Latour ...

Stability Analysis Of Kernel Quality Traits In Exotic-Derived Doubled Haploid Maize Lines, Adam Vanous, Candice Gardner, Michael Blanco, Adam Martin-Schwarze, Jinyu Wang, Xianran Li, Alexander E. Lipka, Sherry Flint-Garcia, Martin Bohn, Jode Edwards, Thomas Lubberstedt

Agronomy Publications

Variation in kernel composition across maize (Zea mays L.) germplasm is affected by a combination of the plant’s genotype, the environment in which it is grown, and the interaction between these two elements. Adapting exotic germplasm to the US Corn Belt is highly dependent on the plant’s genotype, the environment where it is grown, and the interaction between these components. Phenotypic plasticity is ill-defined when specific exotic germplasm is moved over large latitudinal distances and for the adapted variants being created. Reduced plasticity (or stability) is desired for the adapted variants, as it allows for a more rapid ...

Solvation Thermodynamic Mapping In Computer Aided Drug Design, Steven Ramsey

All Dissertations, Theses, and Capstone Projects

The displacement of water from surfaces upon biomolecular recognition and association makes a significant contribution to the free energy changes of these processes. We therefore posit that accurate characterization of local structural and thermodynamic molecular water properties can improve computational model accuracy and predictivity of recognition and association processes. In this thesis, we discuss Solvation Thermodynamic Mapping (STM) methods that we have developed using inhomogeneous fluid solvation theory (IST) to better characterize active site water structural and thermodynamic properties on protein surfaces and the open source tools that we have developed, GIST-CPPTRAJ and SSTMap, which implement these methods which we ...

Co-Expression Of Vegf And Il-6 Family Cytokines Is Associated With Decreased Survival In Her2 Negative Breast Cancer Patients: Subtype-Specific Il-6 Family Cytokine-Mediated Vegf Secretion, Ken Tawara, Hannah Scott, Jacqueline Emathinger, Alex Ide, Ryan Fox, Daniel Greiner, Dollie Lajoie, Danielle Hedeen, Madhuri Nandakumar, Andrew J. Oler, Ryan Holzer, Cheryl Jorcyk

Biology Faculty Publications and Presentations

Breast cancer cell-response to inflammatory cytokines such as interleukin-6 (IL-6) and oncostatin M (OSM) may affect the course of clinical disease in a cancer subtype-dependent manner. Furthermore, vascular endothelial growth factor A (VEGF) secretion induced by IL-6 and OSM may also be subtype-dependent. Utilizing datasets from Oncomine, we show that poor survival of invasive ductal carcinoma (IDC) breast cancer patients is correlated with both high VEGF expression and high cytokine or cytokine receptor expression in tumors. Importantly, epidermal growth factor receptor-negative (HER2-), but not HER2-positive (HER2+), patient survival is significantly lower with high tumor co-expression of VEGF and OSM, OSMRβ ...

Data Evidencing Slow Anaerobic Digestion In Emergency Treatment And Disposal Of Infectious Animal Carcasses, Jacek A. Koziel, Heekwon Ahn, Thomas D. Glanville, Timothy S. Frana, J. (Hans) Van Leeuwen, Lam T. Nguyen

Agricultural and Biosystems Engineering Publications

Burial of infectious and potentially infectious livestock and poultry animals is the most common response to an emergency situation. The data set summarizes 22-week-long experiment that simulates the environment found within conventional burial trenches for emergency disposal of animal carcasses, worldwide, sometimes with a topical application of quicklime as it is required in the Republic of Korea. This data set shows the rarely presented evidence of the extremely slow decay of animal carcasses. Besides visual evidence of no visible breakdown of carcass material, i.e., carcass (or carcass quarters and coarse cuts) still resembled the initial material at the end ...

Identifying Genetic Regulators Of Cancer Stem Cell Differentiation For Glioblastoma Therapy, Ann Chen, Yang Xiao, Rong Fan, Jiangbing Zhou

Yale Day of Data

Glioblastoma multiforme (GBM) is the most common and aggressive type of primary brain cancer. Even with treatment, GBM patients have a median survival rate of less than 15 months and a five-year survival rate of 2%. Poor therapeutic outcomes may be attributed to the presence of a subpopulation of cells within tumors, known as cancer stem cells (CSCs), which are resistant to conventional radiotherapy and chemotherapy. CSCs are capable of tumor initiation, sustained self-renewal, and differentiation into terminal cell types. These terminally differentiated cells make up the bulk of the tumor and are sensitive to GBM therapies. Therefore, CSC-directed therapies ...

Gene Co-Expression Networks Analysis Reveal Novel Molecular Endotypes In Alpha-1 Antitrypsin Deficiency, Jen-Hwa Chu, Wenlan Zang

Yale Day of Data

Rationale:Alpha-1 antitrypsin deficiency (AATD) is a genetic condition that predisposes to early onset pulmonary emphysema and airways obstruction. The exact mechanism through which AATD leads to lung disease is incompletely understood.

Objectives: To investigate the effect of AAT genotype and augmentation therapy on bronchoalveolar lavage (BAL) and peripheral blood mononuclear cells (PBMC) transcriptome, while examining the link between gene expression profiles, and clinical features of AATD.

Methods: We performed RNA-Seq on RNA extracted from BAL and PBMC on samples obtained from 89 AATD patients enrolled in the Genomic Research in Alpha-1 Antitrypsin Deficiency and Sarcoidosis (GRADS) study. Differential gene ...

Non-Invasive Analysis Of The Sputum Transcriptome Discriminates Clinical Phenotypes Of Asthma, Xiting Yan

Yale Day of Data

Whole transcriptome wide gene expression profiles in the sputum and circulation from 100 asthma patients were measured using the Affymetrix HuGene 1.0ST arrays. Unsupervised clustering analysis based on pathways from KEGG were used to identify TEA clusters of patients from the sputum gene expression profiles. The identified TEA clusters have significantly different pre-bronchodilator FEV1, bronchodilator responsiveness, exhaled nitric oxide levels, history of hospitalization for asthma and history of intubation. Evaluation of TEA clusters in children from Asthma BRIDGE cohort confirmed the identified differences in intubation and hospitalization. Furthermore, evaluation of the TH2 gene signatures suggested a much lower prevalence ...

A Novel Pathway-Based Distance Score Enhances Assessment Of Disease Heterogeneity In Gene Expression, Yunqing Liu, Xiting Yan

Yale Day of Data

Distance-based unsupervised clustering of gene expression data is commonly used to identify heterogeneity in biologic samples. However, high noise levels in gene expression data and the relatively high correlation between genes are often encountered, so traditional distances such as Euclidean distance may not be effective at discriminating the biological differences between samples. In this study, we developed a novel computational method to assess the biological differences based on pathways by assuming that ontologically defined biological pathways in biologically similar samples have similar behavior. Application of this distance score results in more accurate, robust, and biologically meaningful clustering results in both ...

Analyzing Neuronal Dendritic Trees With Convolutional Neural Networks, Olivier Trottier, Jonathon Howard

Yale Day of Data

In the biological sciences, image analysis software are used to detect, segment or classify a variety of features encountered in living matter. However, the algorithms that accomplish these tasks are often designed for a specific dataset, making them hardly portable to accomplish the same tasks on images of different biological structures. Recently, convolutional neural networks have been used to perform complex image analysis on a multitude of datasets. While applications of these networks abound in the technology industry and computer science, use cases are not as common in the academic sciences. Motivated by the generalizability of neural networks, we aim ...

A Three State Model Can Explain The Dynamics Of Class Iv Drosophila Dendritic Tips, Sabyasachi Sutradhar

Yale Day of Data

No abstract provided.

Exploring The Ipf Lung Through The Lens Of Single Cell Rna Sequencing, Taylor Adams, Jonas Schupp

Yale Day of Data

This poster illustrates the differences between the IPF disease-specific variety of lung macrophages and the two varieties of macrophages known to reside in the normal human lung.

1915 - Monterey County, California - Lands For Wealth, Fruit For Health; Arthur Dunn

Miscellaneous Monterey and San Luis Obispo County Documents and Reports

It was the aim of this booklet to direct attention to the advantages and opportunities found in Monterey County in 1915 for those who were seeking homes. The hope was that the publication would induce further settlement, for there was a vast amount of territory awaiting development. A marketing publication prepared by Sunset Magazine Homeseekers' Bureau for the Monterey County Board of Supervisors, the publication described in detail the bountiful agricultural opportunities, especially when irrigation and pumping were utilized. The document contains a: 1) description of existing irrigation systems, as well as a vision for the future of irrigation and ...

1913 - Water Resources Of California, Part Iii, Water-Supply Paper 300

Miscellaneous Documents and Reports

The water available for irrigation and domestic supply was the chief factor in the development of southern California, which then had a population of more than 1,000,000 people. The many mountain streams of California afforded abundant hydroelectric power, the utilization of which in manufacturing enterprises and in transportation had been made possible by the progress of electric-power transmission during the previous decade.

Information concerning the quantity of water carried by the streams had been and would continue to be an important factor in the development of these resources, for the fundamental importance of stream-flow data was so thoroughly ...

1920 - Irrigation Of Twelve Million Acres In The Valley Of California; Robert Bradford Marshall

Miscellaneous Documents and Reports

By 1920, California's potential wealth in land reached into billions of dollars; 12,000,000 acres of available agricultural lands remained practically untouched. Marshall proposed a large plan that would make the Valley of California the world's greatest garden. The engineering plans for such a project must be comprehensive, for their execution must not only assure the complete reclamation of 12,000,000 acres of valley lands but must also effectively and forever control the river floods and insure safe and continuous river navigation throughout the year. The hydro-electric current generated along most of the streams would furnish ...

1938 - Quarterly Chapter Of State Mineralogist's Report Xxxiv, California Journal Of Mines And Geology

Miscellaneous Documents and Reports

Report of the development of mining resources and mining activities in each of the four field districts (Redding, Auburn, San Francisco and Los Angeles) were prepared by the District Engineer.

The Effect Of Nonassociative Learning On Oxidative Stress In Caenorhabditis Elegans: A Potential Application For Alzheimer’S Disease Research, Gillian Patton

Journal of the South Carolina Academy of Science

Alzheimer’s disease results in learning and memory deficits due to toxic changes in the brain caused by amyloid-β plaques and oxidative stress. Oxidative stress is caused by the overproduction of free radicals, which are uncharged molecules containing an unpaired valence electron. Nonassociative learning is a type of cognitive processing that only uses one stimulus instead of two related stimuli. Cognitive processing promotes neural growth and learning, while Alzheimer’s inhibits it. The purpose of this study was to test how nonassociative learning impacts oxidative stress and thus, if it might be considered as a potential treatment option for Alzheimer ...