Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Other Engineering
The Synthesis And Characterization Of A Novel Polysaccharide Hydrogel For Biomedical Applications Including The Treatment Of Malignant Tumors And The Prevention Of Metastatic Disease, Elizabeth Diana Barker
The Synthesis And Characterization Of A Novel Polysaccharide Hydrogel For Biomedical Applications Including The Treatment Of Malignant Tumors And The Prevention Of Metastatic Disease, Elizabeth Diana Barker
Masters Theses
Amygel® is an injectable biodegradable controlled release drug delivery system with adjustable release kinetics determined by varying the concentrations of the polymeric components of the material. Amygel® is a starch based biodegradable hydrogel consisting of an interpenetrating network of physically entangled amylose and amylopectin polymer chains crosslinked with d-glucaric acid. Amylose and amylopectin are the two components of naturally occurring starch. The immiscibility of the amylose and amylopectin due to differences in solubility parameter and chain size induces phase separation within the network but because the chains entangled during hydrolysis an interpenetrating network is formed. The chemically reactive carboxyl groups …