Operations Research, Systems Engineering and Industrial Engineering Commons^™

Modular Product Architecture’S Decisions Support For Remanufacturing-Product Service System Synergy, Johnson Adebayo Fadeyi

Wayne State University Dissertations

Remanufacturing is identified as the most viable product end-of-life (EOL) management strategy. However, about 80% of manufactured products currently end up as wastes. Besides other benefits, the product service system (PSS) could curtail the main bottlenecks to remanufacturing namely quantity, quality, recovery time of used product, and negative perception of remanufactured products. Therefore, the integration of PSS and remanufacturing has been increasingly recommended as an enhanced product offering. However, an integration that is informed by mathematical analysis is missing. Meanwhile, the variables that bolster the performance of PSS and remanufacturing are substantially influenced by product development (PD) decisions. Among the …

Proactive Coordination In Healthcare Service Systems Through Near Real-Time Analytics, Seung Yup Lee

Wayne State University Dissertations

The United States (U.S.) healthcare system is the most expensive in the world. To improve the quality and safety of care, health information technology (HIT) is broadly adopted in hospitals. While EHR systems form a critical data backbone for the facility, we need improved 'work-flow' coordination tools and platforms that can enhance real-time situational awareness and facilitate effective management of resources for enhanced and efficient care. Especially, these IT systems are mostly applied for reactive management of care services and are lacking when they come to improving the real-time "operational intelligence" of service networks that promote efficiency and quality of …

Reliability Analysis By Considering Steel Physical Properties, Wujun Si

Wayne State University Dissertations

Most customers today are pursuing engineering materials (e.g., steel) that not only can achieve their expected functions but also are highly reliable. As a result, reliability analysis of materials has been receiving increasing attention over the past few decades. Most existing studies in the reliability engineering field focus on developing model-based and data-driven approaches to analyze material reliability based on material failure data such as lifetime data and degradation data, without considering effects of material physical properties. Ignoring such effects may result in a biased estimation of material reliability, which in turn could incur higher operation or maintenance costs.

Recently, …

Data-Driven Modeling For Decision Support Systems And Treatment Management In Personalized Healthcare, Milad Zafar Nezhad

Wayne State University Dissertations

Massive amount of electronic medical records (EMRs) accumulating from patients and populations motivates clinicians and data scientists to collaborate for the advanced analytics to create knowledge that is essential to address the extensive personalized insights needed for patients, clinicians, providers, scientists, and health policy makers. Learning from large and complicated data is using extensively in marketing and commercial enterprises to generate personalized recommendations. Recently the medical research community focuses to take the benefits of big data analytic approaches and moves to personalized (precision) medicine. So, it is a significant period in healthcare and medicine for transferring to a new paradigm. …

A Data-Driven And Mixed Methods Analysis Of Automotive Retail Operations Management, Mark Allen Colosimo

Wayne State University Dissertations

The importance of effective retail operations management has never been more significant. Our research aims to expand the understanding for efficiency and dynamics of franchise outlets within retail networks with a focus on sales performance and profitability. The focus and contribution is the development of an actionable data analytics driven process by which automotive dealerships (retail outlets) can be analyzed to identify areas of opportunity for improvement. In general, automotive dealerships aim to sell product to make a profit, the manufacturer of the product/brand desires to sell vehicles to make a profit, and the customer desires to find a suitable …

An Agile Quality Management System For Laboratory Developed Tests, Rita D'Angelo

Wayne State University Dissertations

ABSTRACT

AN AGILE QUALITY MANAGEMENT SYSTEM FOR LABORATORY DEVELOPED TESTS

By

RITA D’ANGELO

MAY 2017

Advisor: Dr. Ratna Babu Chinnan

Major: Industrial & Systems Engineering

Degree: Doctor of Philosophy Statement of the Problem: We explore the 2014 draft guidance by the FDA entitled Framework for Regulatory Oversight of Laboratory Developed Tests (LDT) extended from the medical device industry and discuss how these requirements may be applicable to laboratory medicine. We introduce terms, definitions and provide a call for action for leaders to prepare for the potential adherence to regulatory requirements and explore if compliance was achievable in a laboratory environment …

Enhancing Set-Based Design To Engineer Resilience For Long-Lived Systems, Gregory Hartman

Wayne State University Dissertations

At the heart of Set-Based Design is the concept that down-select decisions are deferred until sufficient information is available to make a decision, i.e., a set of possible solutions is maintained. Due to the extended service lives of many of our current and future systems, the horizon for accurately predicting the system’s requirement is shorter than the service life, so the needed information to down-select to a single optimized solution is unavailable at the time of fielding. Set-Based Design can, however, be extended to explicitly carry a set of possible solutions past the point of the initial fielding of the …

Influential Factors In Consumer's Adoption Of Innovative Products, Mahdokht Kalantari

Wayne State University Dissertations

This dissertation addresses the challenges involved with the process of diffusion of innovations in the contexts of innovative educational materials and technological innovations.

Chapters 2 and 3 discuss building and using Online Brand Communities (OBCs) to disseminate innovative math educational materials. OBCs are known to be important platforms where consumers can communicate with the brand as well as other consumers. Through the effective use of these platforms, brands could accelerate the process of diffusion of their innovations. However, OBCs will not survive if consumers do not get engaged and participate in these communities. The purpose of this section of the …

Venous Thromboembolism (Vte) Harm Measurement And Risk Assessment In Real-Time Using Electronic Health Records(Ehr), Seyed Mani Marashi

Wayne State University Dissertations

Venous Thromboembolism (VTE) is a deadly disease and is considered as one of the top reasons for avoidable hospital deaths in the United States and around the world. Patients who survive this disease often must face life-long complications such as Post-thrombotic syndrome (PTS), Chronic thromboembolic pulmonary hypertension (CTPH), etc. Therefore, it is important to monitor and reduce the number of VTE instances in hospitals. This study shows how Electronic Health Records (EHRs) can be utilized to achieve this goal.

First, a new near real-time VTE harm measurement model was developed. Not only the developed model can deliver near real-time results, …