Operations Research, Systems Engineering and Industrial Engineering Commons^™

Achieving Totally Local Anticoagulation On Blood Contacting Devices, Rana Gbyli, Anna Mercaldi, Harihara Sundaram, Kagya Amoako

Mechanical and Industrial Engineering Faculty Publications

The recent years have witnessed an increased activity in biocompatibility research aimed at limiting biomaterial-induced blood coagulation. From 2008 to 2016, a total of $36,946,764.00 USD was awarded in grants to 213 research proposals and as large as 50.4% ($18,627,854.00) of that award monies were distributed to 101 proposals over the fiscal years of FY14 to FY16 alone. However, the complexity in blood responses to biomaterials, variability in blood function between individuals and animal species, and differences in medical device application and test setting all continue to pose difficulties in making a breakthrough in this field. This review focuses on …

Strategic Level Proton Therapy Patient Admission Planning: A Markov Decision Process Modeling Approach, Shengfan Zhang, Ridvan Gedik, Chase Rainwater

Mechanical and Industrial Engineering Faculty Publications

A relatively new consideration in proton therapy planning is the requirement that the mix of patients treated from different categories satisfy desired mix percentages. Deviations from these percentages and their impacts on operational capabilities are of particular interest to healthcare planners. In this study, we investigate intelligent ways of admitting patients to a proton therapy facility that maximize the total expected number of treatment sessions (fractions) delivered to patients in a planning period with stochastic patient arrivals and penalize the deviation from the patient mix restrictions. We propose a Markov Decision Process (MDP) model that provides very useful insights in …

A Constraint Programming Approach For The Team Orienteering Problem With Time Windows, Ridvan Gedik, Emre Kirac, Ashlea Bennet Milburn, Chase Rainwater

Mechanical and Industrial Engineering Faculty Publications

The team orienteering problem with time windows (TOPTW) is a NP-hard combinatorial optimization problem. It has many real-world applications, for example, routing technicians and disaster relief routing. In the TOPTW, a set of locations is given. For each, the profit, service time and time window are known. A fleet of homogenous vehicles are available for visiting locations and collecting their associated profits. Each vehicle is constrained by a maximum tour duration. The problem is to plan a set of vehicle routes that begin and end at a depot, visit each location no more than once by incorporating time window constraints. …

Carbon Footprint Stock Analysis Of U.S. Manufacturing: A Time Series Input-Output Lca, Gokhan Egilmez, Khurrum Bhutta, Bulent Erenay, Yong Shin Park, Ridvan Gedik

Mechanical and Industrial Engineering Faculty Publications

The purpose of this paper is to provide an input-output life cycle assessment model to estimate the carbon footprint of US manufacturing sectors. To achieve this, the paper sets out the following objectives: develop a time series carbon footprint estimation model for US manufacturing sectors; analyze the annual and cumulative carbon footprint; analyze and identify the most carbon emitting and carbon intensive manufacturing industries in the last four decades; and analyze the supply chains of US manufacturing industries to help identify the most critical carbon emitting industries.

Survey Of Lean Management Practices In Pakistani Industrial Sectors, Khurrum Bhutta, Gokhan Egilmez, Kamran Chatha, Faizul Huq

Mechanical and Industrial Engineering Faculty Publications

This research was undertaken to study the implementation and adoption of Lean management practices across several industrial sectors in Pakistan. A total of 100 companies were surveyed across five industries. The objective was to determine if there was disparity in the implementation of Lean practices and to provide a yardstick to measure that disparity. Furthermore, this study identified Lean management best practices across several industries in Pakistan, thus providing benchmarks for other industrial sectors. The data collected was analysed using various descriptive statistical methods. The results indicated robust adoption and implementation of Lean practices in Pakistani industry, though there were …

From Green Buildings To Green Supply Chains: An Integrated Input Output Life Cycle Assessment And Optimization Framework For Carbon Footprint Reduction Policy Making, N. Muhammad Aslaam, Gokhan Egilmez, Murat Kucukvar, M.Khurrum S. Butta

Mechanical and Industrial Engineering Faculty Publications

Purpose: This paper focuses on tracing GHG emissions across the supply chain industries associated with the U.S. residential, commercial and industrial building stock and provides optimized GHG reduction policy plans for sustainable development.

Design/Methodology/Approach: A two-step hierarchical approach is developed. Firstly, Economic Input Output-based Life Cycle Assessment (EIO-LCA) is utilized to quantify the GHG emissions associated with the U.S. residential, commercial and industrial building stock. Secondly, a mixed integer linear programming (MILP) based optimization framework is developed to identify the optimal GHG emissions’ reduction (%) for each industry across the supply chain network of the U.S. economy.

Findings: The results …