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Operations Research, Systems Engineering and Industrial Engineering Commons

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Full-Text Articles in Operations Research, Systems Engineering and Industrial Engineering

Effects Of Ergonomic Worksite Changes On Risks For Cumulative Trauma Disorders Of The Upper Body In An Assembly And Press Operation Job, David B. Mahone Dec 1994

Effects Of Ergonomic Worksite Changes On Risks For Cumulative Trauma Disorders Of The Upper Body In An Assembly And Press Operation Job, David B. Mahone

Theses

Cumulative trauma of the upper body is associated with a variety of individual and job factors. An effort to optimize the human-hardware interface to minimize cumulative trauma is favored. Workers in a set of jobs had complained about hand/wrist and shoulder discomfort. One job was selected for testing alternate machine controls and worksite layout. Electromyography was used to test muscle activity, and photogoniometry was used to measure posture.

For the group of ten worker-subjects, statistically significant decreases in hand/wrist and shoulder muscle activity were found. A marginal, but significant increase in neck muscle activity was also found. When ...


Process Hazard Review For Drug Development, Rudolph R. Schwarz May 1987

Process Hazard Review For Drug Development, Rudolph R. Schwarz

Theses

The development of drugs has become increasingly complex, requiring the use of a wide variety of pharmaceutical actives and isolated intermediates, a majority of which are not always completely characterized with respect to their hazard potential. This can present a source of potential exposure to those who handle these substances during initial drug development, manufacturing of the drug active and ultimately the finished pharamaceutical product. It is, therefore, essential that safety and health information be documented and communicated during the entire drug development process.

The need for application of process hazard review techniques to the development of new drug materials ...