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- Keyword
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- AgNP; IL-1β; Inflammation; Liposomal-AgNP; Pro-inflammatory cytokines; TNF-α (1)
- DPPC-based liposome (1)
- Methods for enhanced cytotoxicity (1)
- Nanodiamonds; nanoscale magnetic resonance imaging (nano-MRI); nitrogen-vacancy center; optically detected magnetic resonance (1)
- Silver nanoparticle encapsulation (1)
Articles 1 - 3 of 3
Full-Text Articles in Nanoscience and Nanotechnology
Nitrogen-Vacancy Centers In Diamond For Nanoscale Magnetic Resonance Imaging Applications, Alberto Boretti, Lorenzo Rosa, Jonathan Blackledge, Stefania Castelletto
Nitrogen-Vacancy Centers In Diamond For Nanoscale Magnetic Resonance Imaging Applications, Alberto Boretti, Lorenzo Rosa, Jonathan Blackledge, Stefania Castelletto
Articles
The nitrogen-vacancy (NV) center is a point defect in diamond with unique properties for use in ultra-sensitive, high-resolution magnetometry. One of the most interesting and challenging applications is nanoscale magnetic resonance imaging (nano-MRI). While many review papers have covered other NV centers in diamond applications, there is no survey targeting the specific development of nano-MRI devices based on NV centers in diamond. Several different nano-MRI methods based on NV centers have been proposed with the goal of improving the spatial and temporal resolution, but without any coordinated effort. After summarizing the main NV magnetic imaging methods, this review presents a …
Surface Modification Of Silver Nanoparticle (Agnp) By Liposomal Encapsulation Mitigates Agnp-Induced Inflammation, Azeez O. Yusef, Alan Casey
Surface Modification Of Silver Nanoparticle (Agnp) By Liposomal Encapsulation Mitigates Agnp-Induced Inflammation, Azeez O. Yusef, Alan Casey
Articles
Silver nanoparticles (AgNP) are widely used in a variety of consumable products as antibacterial to prevent or treat infection. Unfortunately, evidence exits that AgNP induces inflammation which can worsen with repeated human exposure. However, there is little or no research on how to mitigate these adverse effects due to AgNP induced-toxicity. Here, we investigated if surface modification of AgNP by liposomal encapsulation suppresses AgNP-mediated inflammatory responses in THP1 monocytes and THP1 differentiated macrophages (TDM). AgNP was encapsulated in a dipalmitoyl phosphatidyl choline- (DPPC)/cholesterol-based liposome by extrusion through a 100-nm polycarbonate membrane to form Lipo-AgNP. It was found as expected that …
Evaluation Of Silver Nanoparticle Encapsulation In Dppc-Based Liposome By Different Methods For Enhanced Cytotoxicity, Azeez O. Yusef, Alan Casey
Evaluation Of Silver Nanoparticle Encapsulation In Dppc-Based Liposome By Different Methods For Enhanced Cytotoxicity, Azeez O. Yusef, Alan Casey
Articles
Here we carried out a comparative study on two cost and time effective methods of encapsulating silver nanoparticles (AgNP) in dipalmitoyl-phosphatidyl choline (DPPC)/cholesterol-based liposome to enhance nanoparticle cytotoxicity, and evaluated the effect of this on a blood cell line (THP1 monocytes) often involved in uptake of nanoparticles during human exposure. DLS and Zeta potential analyses over a 6-months period showed the extruded Lipo-AgNP (Ex-Lipo-AgNP) exhibited more stable characteristics when compared with the probe-sonicated Lipo-AgNP (PB-Lipo-AgNP). SEM microscopy indicated agglomeration of the PB-Lipo-AgNP which was not observed in Ex-Lipo-AgNP. Ex-Lipo-AgNP also exhibited higher temperature-dependent stability with 35.3% reduction in size from …