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Nanoscience and Nanotechnology Commons

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2013

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Mechanical Engineering Publications

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Full-Text Articles in Nanoscience and Nanotechnology

A Simple Add-On Microfluidic Appliance For Accurately Sorting Small Populations Of Cells With High Fidelity, Michael Grad, Erik F. Young, Lubomir Smilenov, David J. Brenner, Daniel Attinger Nov 2013

A Simple Add-On Microfluidic Appliance For Accurately Sorting Small Populations Of Cells With High Fidelity, Michael Grad, Erik F. Young, Lubomir Smilenov, David J. Brenner, Daniel Attinger

Mechanical Engineering Publications

Current advances in single cell sequencing, gene expression and proteomics require the isolation of single cells, frequently from a very small source population. In this work we describe the design and characterization of a manually operated microfluidic cell sorter that (1) can accurately sort single or small groups of cells from very small cell populations with minimal losses, (2) that is easy to operate and that can be used in any laboratory that has a basic fluorescent microscope and syringe pump, (3) that can be assembled within minutes, (4) that can sort cells in very short time (minutes) with minimum ...


Book Review: Nanoelectric Devices By Byung-Gook Park, Sung Woo Huang And Young June Park, Ganesh Balasubramanian Jul 2013

Book Review: Nanoelectric Devices By Byung-Gook Park, Sung Woo Huang And Young June Park, Ganesh Balasubramanian

Mechanical Engineering Publications

The importance of nanoelectronics is enormous given the constant demand for enhancement in performance of electronic and computing devices. While Moore's law predicted the exponential increase in the power of processing units, the associated device level physics have brought about a new set of interdisciplinary challenges. Miniaturization of transistors has been the key to the unprecedented growth of microelectronics and its gradual transition to lower length scales. However, system sizes at the nanoscale being comparable to the mean free paths of the charge carriers (electrons), additional considerations in the transport processes need to be accounted for to obtain a ...