- Delivery platform (1)
- Genetics (1)
- Organohalide-respiring microorganisms (1)
- Groundwater remediation (1)
- Cell surface biomolecules (1)
Articles 1 - 3 of 3
Full-Text Articles in Nanoscience and Nanotechnology
Field Scale Application Of Nanoscale Zero Valent Iron: Mobility, Contaminant Degradation, And Impact On Microbial Communities, Chris M.D. Kocur
Electronic Thesis and Dissertation Repository
This thesis began by verifying that nanoscale zero valent iron (nZVI) synthesis methods could be scaled up and implemented at the field scale in a safe manner. This led to successful demonstration of nZVI injection and mobility under constant head gravity injection into a contaminated utility corridor in Sarnia, Ontario. Where field studies have fallen short in the past was linking the somewhat qualitative field geochemical parameters to other evidence of nZVI transport. Definitive nZVI detection was elusive in previous field studies due to the highly reactive nature of the particles caused by their high surface area. nZVI was detected ...
Integrated Nanoscale Imaging And Spatial Recognition Of Biomolecules On Surfaces, Congzhou Wang
Theses and Dissertations
Biomolecules on cell surfaces play critical roles in diverse biological and physiological processes. However, conventional bulk scale techniques are unable to clarify the density and distribution of specific biomolecules in situ on single, living cell surfaces at the micro or nanoscale. In this work, a single cell analysis technique based on Atomic Force Microscopy (AFM) is developed to spatially identify biomolecules and characterize nanomechanical properties on single cell surfaces. The unique advantage of these AFM-based techniques lies in the ability to operate in situ (in a non-destructive fashion) and in real time, under physiological conditions or controlled micro-environments.
First, AFM-based ...
Development Of Gold Nanoparticle-Based Antigen Delivery Platform For Vaccines Against Hiv-1, Feng Lin
Graduate Theses and Dissertations
As one of the world’s most devastating viruses, HIV-1 has killed more than 39 million people, and around two million cases of newly infected individuals are recorded every year. However, no effective vaccine has been developed to stop this pandemic since its onset in the 1980s. Since vaccine development is moving slowly, delivery platforms as an essential element to enhance both the efficiency and efficacy of vaccines have drawn increased attention. Gold nanoparticles (GNPs) as a novel delivery platform has been studied in drug and vaccine delivery. My research goal is to apply this delivery platform in the AIDS ...