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Full-Text Articles in Nanoscience and Nanotechnology
Halloysite Clay Nanotubes For Controlled Delivery Of Chemically Active Agents, Elshard Abdullayev
Halloysite Clay Nanotubes For Controlled Delivery Of Chemically Active Agents, Elshard Abdullayev
Doctoral Dissertations
In this work we explored the capabilities of halloysite nanotubes as capsules for encapsulation and controlled delivery of the chemically and biologically active substances. Halloysite is a two-layered aluminosilicate which has a predominantly hollow tubular structure in the submicron range and is chemically similar to kaolinite [1, 2].
In the first section of this work, we analyzed the structure of the halloysite nanotubes as well as its capability to encapsulate and deliver biologically and chemically active agents, similarities and differences between release characteristics of different agents and how these differences relate with their chemical structure. Models were used to describe …
Surface Morphology Of Platelet Adhesion Influenced By Activators, Inhibitors And Shear Stress, Melanie Groan Watson
Surface Morphology Of Platelet Adhesion Influenced By Activators, Inhibitors And Shear Stress, Melanie Groan Watson
Doctoral Dissertations
Platelet activation involves multiple events, one of which is the generation and release of nitric oxide (NO), a platelet aggregation inhibitor. Platelets simultaneously send and receive various agents that promote a positive and negative feedback control system during hemostasis. Although the purpose of platelet-derived NO is not fully understood, NO is known to inhibit platelet recruitment. NO's relatively large diffusion coefficient allows it to diffuse more rapidly than platelet agonists. It may thus be able to inhibit recruitment of platelets near the periphery of a growing thrombus before agonists have substantially accumulated in those regions.
Results from two studies in …
An Improved Layer-By-Layer Self-Assembly Technique To Generate Biointerfaces For Platelet Adhesion Studies: Dynamic Lbl, Juan Manuel Lopez
An Improved Layer-By-Layer Self-Assembly Technique To Generate Biointerfaces For Platelet Adhesion Studies: Dynamic Lbl, Juan Manuel Lopez
Doctoral Dissertations
Layer-by-layer self-assembly (LbL) is a technique that generates engineered nano-scale films, coatings, and particles. These nanoscale films have recently been used in multiple biomedical applications. Concurrently, microfabrication methods and advances in microfluidics are being developed and combined to create "Lab-on-a-Chip" technologies. The potential to perform complex biological assays in vitro as a first-line screening technique before moving on to animal models has made the concept of lab on a chip a valuable research tool.
Prior studies in the Biofluids Laboratory at Louisiana Tech have used layer-by-layer and in vitro biological assays to study thrombogenesis in a controlled, repeatable, engineered environment. …
Analysis Of Conjugated Polymer Nanotubules Formed By Template Wetting Nanofabrication, Steven D. Bearden Jr.
Analysis Of Conjugated Polymer Nanotubules Formed By Template Wetting Nanofabrication, Steven D. Bearden Jr.
Doctoral Dissertations
Semiconducting and optoelectric conjugated polymers have potential in micro and nano-electronic applications. Their widely tunable physical conformations and orientations make these polymers ideal material for engineering small scale devices. The polymers have been incorporated into several electronic devices including light-emitting diodes, solar cells, and field-effect transistors. Widespread adoption of these materials will not be a reality until the issues of poor device performance, short lifespans, and device degradation are resolved.
Nanostructures have been demonstrated to have improvements in molecular ordering and electronic transport. In the work presented here, tubular nanostructures of conjugated polymers fabricated by the template wetting nanofabrication process …