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Nanoparticles

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Full-Text Articles in Nanoscience and Nanotechnology

Carbon-Supported Transition Metal Nanoparticles For Catalytic And Electromagnetic Applications, Kavita Meduri Nov 2018

Carbon-Supported Transition Metal Nanoparticles For Catalytic And Electromagnetic Applications, Kavita Meduri

Dissertations and Theses

Recently, there has been growing interest in using transition metals (TM) for catalytic and electromagnetic applications, due to the ability of TMs to form stable compounds in multiple oxidation states. In this research, the focus has been on the synthesis and characterization of carbon-supported TM nanoparticles (NPs), specifically palladium (Pd) and gold (Au) NPs, for catalytic applications, and transition metal oxides (TMO) NPs, specifically Fe3O4 NPs for electromagnetic applications. Carbon supports have several advantages, such as enabling even distribution of particles, offering large specific surface area with excellent electron conductivity, and relative chemical inertness.

In this dissertation ...


A New Approach To The Development Of An Rsv Anti-Viral Targeted Nanocarrier For Dual Inhibition Of Viral Infection And Replication, Anthony N. Singer Jun 2018

A New Approach To The Development Of An Rsv Anti-Viral Targeted Nanocarrier For Dual Inhibition Of Viral Infection And Replication, Anthony N. Singer

Graduate Theses and Dissertations

Respiratory Syncytial Virus (RSV) is a potentially life-threatening respiratory pathogen that infects approximately 64 million children and immunocompromised adults globally per year. Currently, there is a need for prophylactic and therapeutic approaches effective against primary and secondary RSV infections. This project focuses on the development of a simple, smart, and scalable anti-RSV nanotherapeutic that combines novel cellular antiviral defense mechanisms targeting the inhibition of viral fusion and replication. An ICAM-1 targeted liposomal nanocarrier will be synthesized and coated with a layer of chitosan containing the anti-fusion HR2-D peptide as an extracellular defense mechanism. Additionally, chitosan complexed to dual expressing short ...


Mesoscale Computational Studies Of Thin-Film Bijels, Joseph M. Carmack May 2018

Mesoscale Computational Studies Of Thin-Film Bijels, Joseph M. Carmack

Theses and Dissertations

Bijels are a relatively new class of soft materials that have many potential applications in the technology areas of energy, medicine, and environmental sustainability. They are formed by the arrest of binary liquid spinodal decomposition by a dispersion of solid colloidal nanoparticles. This dissertation presents an in-depth simulation study of Bijels constrained to thin-film geometries and in the presence of electric fields. We validate the computational model by comparing simulation results with previous computational modeling and experimental research. In the absence of suspended particles, we demonstrate that the model accurately captures the rich kinetics associated with diffusion-based surface-directed spinodal decomposition ...


Surface Area And Electrocatalytic Properties Of Feni Nanoparticles For The Oxygen Evolution Reaction (Oer), James Burrow May 2018

Surface Area And Electrocatalytic Properties Of Feni Nanoparticles For The Oxygen Evolution Reaction (Oer), James Burrow

Chemical Engineering Undergraduate Honors Theses

Iron-nickel bimetallic electrocatalysts have recently emerged as some of the best candidates for the oxygen evolution reaction (OER) in alkaline electrolyte. Understanding the effects of composition and morphology of iron-nickel nanoparticles is crucial for optimization and enhanced electrocatalyst performance. Both physical surface area and electrochemical surface area (ECSA) are functions of morphology. In this study, four different iron-nickel nanoparticle catalysts were synthesized. The catalysts were varied based on morphology (alloy versus core-shell) and composition (low, medium, and high stabilizer concentration). Brunauer-Emmett-Teller (BET) surface area analysis was conducted on three of the synthesized iron-nickel nanoparticles using a physisorption analyzer while electrochemical ...


Plasmonic And Upconversion Nanoparticles For Bladder Cancer Treatment, Suehyun Katherine Cho Apr 2018

Plasmonic And Upconversion Nanoparticles For Bladder Cancer Treatment, Suehyun Katherine Cho

Electrical, Computer & Energy Engineering Graduate Theses & Dissertations

This thesis reports syntheses and surface modifications of various nanoparticles, including plasmonic, upconversion, and indium tin oxide nanoparticles for in situ bladder cancer detection and treatment.

The first part of this thesis reports a new and efficient polyethylene glycol (PEG) coating of gold nanorods (AuNRs). This coating technique is proven not only to be more stable in water compared to conventional coating methods, but also allows conjugation of an anti-epidermal growth factor receptor, C-225 antibodies. The AuNRs conjugated with C-225 antibodies (CNR) is then used in both in vitro and in vivo settings to demonstrate specific, targeted treatment capabilities by ...


Effect Of Nanoparticle Additives On The Tribological Behavior Of Oil Under Boundary Lubrication, Yosef Jazaa Jan 2018

Effect Of Nanoparticle Additives On The Tribological Behavior Of Oil Under Boundary Lubrication, Yosef Jazaa

Graduate Theses and Dissertations

In this study, three different nanoparticles (CuO, WC, WS2) of comparable nominal diameter, were added to a Polyalphaolefin (PAO) base oil to evaluate tribological response in the boundary lubrication regime. The concentration of particles was fixed at 1% by weight for this study and different surfactants (Oleic acid, polyisobutylene succinimide) and dispersion methods were employed to determine the impact on agglomeration and the observed tribological response. The results showed that of the methods studied, adding 10 % Oleic acid (OA) while sonicating the particles for 30 minutes reduced the agglomeration the most and adding 1% Oleic acid while sonicating the particles ...


Macromolecular Soft Templates For Synthesis And Self-Assembly Of Functional Nanomaterials, Srikanth Nayak Jan 2018

Macromolecular Soft Templates For Synthesis And Self-Assembly Of Functional Nanomaterials, Srikanth Nayak

Graduate Theses and Dissertations

Nanostructured composite materials made of organic matrices and inorganic nanoparticles (NPs) represent the new paradigm of functional hybrid materials. This dissertation is focused on the synthesis and self-assembly of NPs within organic matrices which act as templates, targeting the formation of use-inspired structures. Particularly, self-assembly of macromolecules such as proteins and polymers, and polymer-functionalized NPs is utilized to create ordered assemblies of NPs. Inspired by the formation of chains of magnetic NPs in a group of bacteria referred to as Magnetotactic bacteria, we used Mms6, a biomineralization protein, as a template towards the formation of self-assembled arrays of magnetic NPs ...


Bottom-Up Approach To Fabricate Nanostructured Thin Films From Colloidal Nanocrystal Precursors, Santosh Shaw Jan 2017

Bottom-Up Approach To Fabricate Nanostructured Thin Films From Colloidal Nanocrystal Precursors, Santosh Shaw

Graduate Theses and Dissertations

Control over microstructures at the nanoscale (<100nm) still seems challenging due to, among other things, the stochastic nature of nucleation in the bulk phase. The densification of assemblies of ligand-capped nanocrystals (colloidal nanocrystal assemblies, CNAs) could bypass this challenge that limits our control over the nanostructure and, therefore, the properties of materials. However, the removal of the ligands and the cracking that follows it are the two critical hurdles that have been stymieing this approach.

We show that low-pressure plasma processing can effectively remove ligands from CNAs (down to 0.6 at.% of carbon which can be accounted for adventitious carbon) without harming the properties of the inorganic cores of the nanoparticles and the structure of CNAs. The cracking of CNAs is correlated with the structure of the CNAs, which can be controlled and easily predicted by Hansen solubility parameters of solvent in which the nanoparticles are dispersed. While a fully solvated ligand shell leads to the formation of close-packed ordered CNAs – which cracked after self-assembly or ligand removal ...


Coarse-Grained Simulations Of The Self-Assembly Of Dna-Linked Gold Nanoparticle Building Blocks, Charles Wrightsman Armistead Dec 2016

Coarse-Grained Simulations Of The Self-Assembly Of Dna-Linked Gold Nanoparticle Building Blocks, Charles Wrightsman Armistead

Theses and Dissertations

The self-assembly of nanoparticles (NPs) of varying shape, size, and composition for the purpose of constructing useful nanoassemblies with tailored properties remains challenging. Although progress has been made to design anisotropic building blocks that exhibit the required control for the precise placement of various NPs within a defined arrangement, there still exists obstacles in the technology to maximize the programmability in the self-assembly of NP building blocks. Currently, the self-assembly of nanostructures involves much experimental trial and error. Computational modeling is a possible approach that could be utilized to facilitate the purposeful design of the self-assembly of NP building blocks ...


Symbiotic Plasmonic Nanomaterials: Synthesis And Properties, Abhinav Malasi May 2016

Symbiotic Plasmonic Nanomaterials: Synthesis And Properties, Abhinav Malasi

Doctoral Dissertations

Metal particles of the dimensions of the order of 1 to 100's of nanometers show unique properties that are not clearly evident in their bulk state. These nanoparticles are highly reactive and sensitive to the changes in the vicinity of the particle surface and hence find applications in the field of sensing of chemical and biological agents, catalysis, energy harvesting, data storage and many more. By synthesizing bimetallic nanoparticles, a single nanoparticle can show multifunctional characteristics. The focus of this thesis is to detail the synthesis and understand the properties of bimetallic nanomaterial systems that show interesting optical, chemical ...


Tracking Silver, Gold, And Titanium Dioxide Nanoparticles Through Drinking Water Systems By Single Particle - Inductively Coupled Plasma - Mass Spectrometry, Ariel Renee Donovan Jan 2016

Tracking Silver, Gold, And Titanium Dioxide Nanoparticles Through Drinking Water Systems By Single Particle - Inductively Coupled Plasma - Mass Spectrometry, Ariel Renee Donovan

Masters Theses

"Single particle (SP)-ICP-MS methods were developed to characterize and quantify Ti-containing, titanium dioxide, silver, and gold NP concentration, size, size distribution and dissolved metal element concentration in surface water and treated drinking water. The effectiveness of conventional drinking water treatments (including lime softening, alum coagulation, filtration, and disinfection) to remove NPs from surface water was evaluated using six-gang stirrer jar test simulations. Six-gang stirrers were used to simulate drinking water treatments including lime softening, alum coagulation, powdered activated carbon sorption, filtration, and disinfection by free chlorine. Lime softening effectively removed most nanoparticles added. Source and drinking waters from three ...


In Vacuo Fabrication And Electronic Structure Characterization Of Atomic Layer Deposition Thin Films, Michael Schaefer Nov 2015

In Vacuo Fabrication And Electronic Structure Characterization Of Atomic Layer Deposition Thin Films, Michael Schaefer

Graduate Theses and Dissertations

Improvement of novel electronic devices is possible by tailor-designing the electronic structure at device interfaces. Common problems observed at interfaces are related to unwanted band alignment caused by the chemical diversity of interface partners, influencing device performance negatively. One way to address this problem is by introducing ultra-thin interfacial dipole layers, steering the band alignment in a desired direction. The requirements are strict in terms of thickness, conformity and low density of defects, making sophisticated deposition techniques necessary. Atomic layer deposition (ALD) with its Ångstrom-precise thickness control can fulfill those requirements.

The work presented here encompasses the implementation of an ...


In Vitro Studies Of Gold And Gold Silica Nanoparticle Radiosensitization With Kilovoltage X-Rays, Gregory Colarch May 2015

In Vitro Studies Of Gold And Gold Silica Nanoparticle Radiosensitization With Kilovoltage X-Rays, Gregory Colarch

UNLV Theses, Dissertations, Professional Papers, and Capstones

Technological advances in the ability to construct and manipulate nanoscale particles have opened up the possibility of using solid metallic nanoparticles and mixed metal nanoshells as a means to increase dose enhancement and treatment efficacy to tumors. In order for nanoparticles to be an effective form of treatment, they must be delivered to tumors in sufficient concentrations so that there is a dose enhancement factor due to ionizing radiation, as well as being essentially non-toxic to healthy cells. Gold nanoparticles and silica-gold nanoshells fit these requirements. Gold has a high atomic number (Z=79), which gives a larger cross section ...


Enhanced Magnetoimpedance And Microwave Absorption Responses Of Soft Ferromagnetic Materials For Biodetection And Energy Sensing, Jagannath Devkota Jan 2015

Enhanced Magnetoimpedance And Microwave Absorption Responses Of Soft Ferromagnetic Materials For Biodetection And Energy Sensing, Jagannath Devkota

Graduate Theses and Dissertations

A combination of magnetic sensors with magnetic nanoparticles offers a promising approach for highly sensitive, simple, and rapid detection of cancer cells and biomolecules. The challenge facing the field of magnetic biosensing is the development of low-cost devices capable of superconducting quantum interference device (SQUID)-like field sensitivity at room temperature. In another area of interest, improving the sensitivity of existing electromagnetic field sensors for microwave energy sensing applications is an important and challenging task. In this dissertation, we have explored the excellent magnetoimpedance and microwave absorption responses of soft ferromagnetic amorphous ribbons and microwires for the development of high-performance ...


On Thermal Aging Prevention In Polymer Core Composite Conductor Rods, Joe D. Hoffman Jan 2015

On Thermal Aging Prevention In Polymer Core Composite Conductor Rods, Joe D. Hoffman

Electronic Theses and Dissertations

Increased energy usage in the United States and worldwide is driving the demand for new technologies to transmit electrical power in greater quantities and with reliable, safe, and more efficient methods. One recent innovation is to replace the standard Aluminum Conductor Steel Reinforced electrical transmission conductor with a new conductor design that utilizes a fiber reinforced polymer core rod to support a fully annealed aluminum conductor. This new technology that includes a hybrid carbon fiber/epoxy and glass fiber/epoxy support core allows for better efficiency and for greater current to be transmitted in the same size and weight line ...


Nanotechnology And Additive Manufacturing Platforms For Clinical Medicine: An Investigation Of 3d Printing Bioactive Constructs And Halloysite Nanotubes For Drug Delivery And Biomaterials, Jeffery A. Weisman Oct 2014

Nanotechnology And Additive Manufacturing Platforms For Clinical Medicine: An Investigation Of 3d Printing Bioactive Constructs And Halloysite Nanotubes For Drug Delivery And Biomaterials, Jeffery A. Weisman

Doctoral Dissertations

Personalized medicine requires the development of new technologies for controlled or targeted drug delivery. Three-dimensional (3D) printing and additive manufacturing techniques can be used to generate customized constructs for bioactive compound delivery. Nanotechnology in the form of nanoparticles, used as a stand-alone construct or for material enhancements, can significantly improve established biomaterials such as PMMA based bone cements or enable new technology to have enhanced capabilities. Combinations of the technologies can be used in such applications as infectious disease treatments, chemotherapeutic targeted drug delivery or targeted delivery of nearly any bioactive compound.

Chemotherapeutic or antibiotic enhanced 3D printing filaments were ...


Nanoscale Manipulation Of Pristine And Functionalized Freestanding Graphene Using Scanning Tunneling Microscopy, Matthew Ackerman Aug 2014

Nanoscale Manipulation Of Pristine And Functionalized Freestanding Graphene Using Scanning Tunneling Microscopy, Matthew Ackerman

Theses and Dissertations

Over the past ten years the 2D material graphene has attracted an enourmous amount of attention from researchers from across diciplines and all over the world. Many of its outstanding electronic properties are present only when it is not interacting with a substrate but is instead freestanding. In this work I demonstrate that pristine and functionalized freestanding graphene can be imaged using a scanning tunneling microscope (STM) and that imaging a flexible 2D surface is fundamentally different from imaging a bulk material due to the attraction between the STM tip and the sample. This attraction can be used to manipulate ...


Developent Of A Phospholipid Encapsulation Process For Quantum Dots To Be Used In Biologic Applications, Logan Grimes Jun 2014

Developent Of A Phospholipid Encapsulation Process For Quantum Dots To Be Used In Biologic Applications, Logan Grimes

Master's Theses and Project Reports

The American Cancer Society predicts that 1,665,540 people will be diagnosed with cancer, and 585,720 people will die from cancer in 2014. One of the most common types of cancer in the United States is skin cancer. Melanoma alone is predicted to account for 10,000 of the cancer related deaths in 2014. As a highly mobile and aggressive form of cancer, melanoma is difficult to fight once it has metastasized through the body. Early detection in such varieties of cancer is critical in improving survival rates in afflicted patients. Present methods of detection rely on visual ...


Preparation Of Supported Metal Catalysts By Atomic And Molecular Layer Deposition For Improved Catalytic Performance, Troy Donald Gould Jan 2014

Preparation Of Supported Metal Catalysts By Atomic And Molecular Layer Deposition For Improved Catalytic Performance, Troy Donald Gould

Chemical & Biological Engineering Graduate Theses & Dissertations

Creating catalysts with enhanced selectivity and activity requires precise control over particle shape, composition, and size. Here we report the use of atomic layer deposition (ALD) to synthesize supported Ni, Pt, and Ni-Pt catalysts in the size regime (< 3 nm) where nanoscale properties can have a dramatic effect on reaction activity and selectivity.

This thesis presents the first ALD synthesis of non-noble metal nanoparticles by depositing Ni on Al2O3 with two half-reactions of Ni(Cp)2 and H2. By changing the number of ALD cycles, Ni weight loadings were varied from 4.7 wt% to 16.7 wt% and the average particle sizes ranged from 2.5 to 3.3 nm ...


Synthesis And Functionalization Of Gold Nanoparticles Using Chemically Modified Ssdna, Philip Gerard Calabrese Jan 2014

Synthesis And Functionalization Of Gold Nanoparticles Using Chemically Modified Ssdna, Philip Gerard Calabrese

Chemistry & Biochemistry Graduate Theses & Dissertations (1986-2018)

In the first part of this thesis, methods for functionalizing spherical gold nanoparticles with nucleic acid binding ligands (aptamers) that target the VEGF receptor complex were developed. In order to provide a multiplexed labeling strategy for imaging the VEGF receptor complex in electron microscopy, gold nanoparticles of distinct sizes were conjugated to modified ssDNA aptamers that target the VEGF-A cytokine, the VEGFR-2 RTK receptor and a membrane associated co-receptor, Nrp-1. The modified ssDNA gold nanoparticle conjugates were applied to a human lung carcinoma cell line (A549) which has been shown to express each of these proteins and used as a ...


The Optical Properties Of Spiky Gold Nanoshells, Simon Hastings Jan 2014

The Optical Properties Of Spiky Gold Nanoshells, Simon Hastings

Publicly Accessible Penn Dissertations

Plasmonic nanoparticles are a powerful and versatile tool for molecular sensing, drug delivery, and cancer treatment. When exposed to incident light, these nanoparticles have greatly increased far-field scattering and near-field enhancement. Spiky gold nanoshells are a recently developed class of nanoparticles composed of sharp gold spikes decorating a polystyrene core. Spiky nanoshells are synthesized using the templated surfactant-assisted seed growth method, which enables extensive control of the nanoparticle morphology. Here, it is shown that these particles have a tailorable far-field resonance, extremely uniform single-particle surface enhanced Raman scattering, and modal interference in dark-field microscopy measurements. Finite-difference time-domain simulations are performed ...


Role Of Surface Chemistry In Nanoscale Electrokinetic Transport, Secuk Atalay Jan 2014

Role Of Surface Chemistry In Nanoscale Electrokinetic Transport, Secuk Atalay

Mechanical & Aerospace Engineering Theses & Dissertations

This dissertation work presents the efforts to study the electrofluidics phenomena, with a focus on surface charge properties in nanoscale systems with the potential applications in imaging, energy conversion, ultrafiltration, DNA analysis/sequencing, DNA and protein transport, drug delivery, biological/chemical agent detection and micro/nano chip sensors.

Since the ion or molecular or particle transport and also liquid confinement in nano-structures are strongly dominated by the surface charge properties, in regards of the fundamental understanding of electrofluidics at nanoscale, we have used surface charge chemistry properties based on 2-pK charging mechanism. Using this mechanism, we theoretically and analytically showed ...


Thermal Conductivity Of Alumina And Silica Nanofluids, Julian Bernal Castellanos Jan 2014

Thermal Conductivity Of Alumina And Silica Nanofluids, Julian Bernal Castellanos

All Theses, Dissertations, and Other Capstone Projects

This thesis studies the effects of the base fluid, particle type/size, and volumetric concentration on the thermal conductivity of Alumina and Silica nanofluids. The effects of base fluid were observed by preparing samples using ethylene glycol (EG), water, and mixtures of EG/water as the base fluid and Al2O3 (10 nm) nanoparticles. The particles type/size and volumetric concentration effects were tested by preparing samples of nanofluids using Al2O3 (10nm), Al2O3 (150nm), SiO2 (15 nm), and SiO2 (80 nm) nanoparticles and ionized water as base fluid at different volumetric concentrations. All samples were mixed using a sonicator for 30 ...


Effect Of Relative Humidity In High Temperature Oxidation Of Ceria Nanoparticles Coating On 316l Austenitic Stainless Steel, Luis Giraldez Pizarro Aug 2013

Effect Of Relative Humidity In High Temperature Oxidation Of Ceria Nanoparticles Coating On 316l Austenitic Stainless Steel, Luis Giraldez Pizarro

Theses and Dissertations

A solution of 20 wt. % colloidal dispersion of Cerium Oxide (CeO2) in 2.5% of acetic acid, was used for depositing a coating film on an austenitic stainless steel 316L. Cerium compounds have been distinguished as potential corrosion inhibitors in coatings over several alloys. The oxidation behavior of the cerium oxide coating on 316L austenitic stainless steel alloy was evaluated in dry and humid environments, the weight changes (W/A) was monitored as a function of time using a custom built Thermogravimetrical Analysis (TGA) instrument at temperatures of 750C, 800C and 850C, and different relative humidity levels (0%, 10% and ...


Plasmonic Nanostructures For The Absorption Enhancement Of Silicon Solar Cells, Nathan Matthias Burford May 2013

Plasmonic Nanostructures For The Absorption Enhancement Of Silicon Solar Cells, Nathan Matthias Burford

Theses and Dissertations

In this work, computational investigation of plasmonic nanostructures was conducted using the commercial finite element electromagnetics solver Ansys® HFSS. Arrays of silver toroid nanoparticles located on the surface of an amorphous silicon thin-film absorbing layer were studied for particle sizes ranging from 20 nm to 200 nm in outer diameter. Parametric optimization by calculating an approximation of the photocurrent enhancement due to the nanoparticles was performed to determine optimal surface coverage of the nanoparticles. A comparison was made between these optimized nanotoroid arrays and optimized nanosphere arrays based on spectral absorption enhancement and potential photocurrent enhancement in an amorphous silicon ...


Dispersion And Self-Assembly Of Anisotropic Plasmonic Nanoparticles In Liquid Crystalline Media, Julian Samuel Goodwin Evans Jan 2013

Dispersion And Self-Assembly Of Anisotropic Plasmonic Nanoparticles In Liquid Crystalline Media, Julian Samuel Goodwin Evans

Physics Graduate Theses & Dissertations

Noble metal nanoparticles possess extraordinary optical properties due to their plasmon modes that make them desirable for inclusion into materials. Non-dipolar plasmon modes are one of the simplest known ways to control the magnetic properties of a material; consequently gold nanoparticles are one of the most promising systems to produce metamaterials. In order to fully utilize the properties of gold nanoparticles for device applications, one needs to control the interparticle spacing, distribution, and orientation of anisotropic gold nanoparticles within a material. Liquid crystalline host materials can allow for alignment and self-assembly of nanoparticles through viscoelastic forces. In this thesis, I ...


Design Of Novel Nano-Carriers For Multi-Enzyme Co-Localization, Feng Jia Jan 2013

Design Of Novel Nano-Carriers For Multi-Enzyme Co-Localization, Feng Jia

Graduate Theses and Dissertations

The widely existing MECs in Nature have inspired researchers to design synthetic analogs to promote the overall catalytic efficiency in vitro by co-localizing multiple enzymes to mimic the MECs' unique functionalities. A number of efforts have been devoted to designing synthetic MECs in the past couples of decades. This thesis work has focused on developing novel strategies based on enzyme immobilization to design nano-carriers for multi-enzyme co-localization to realize kinetics enhancement and strong control of spatial arrangement of the enzymes. Three distinct approaches have been designed using different attachment methods and platforms.

First, the multifunctional polystyrene nanoparticles were designed for ...


Plasmonics Based Micro/Nano Manufacturing, Quincy Jay Garner Jan 2013

Plasmonics Based Micro/Nano Manufacturing, Quincy Jay Garner

Graduate Theses and Dissertations

Since the advent of the Information Age, there has been an ever growing demand to continually shrink and reduce the cost of semiconductor products. To meet this demand, a great amount of research has been done to improve our current micro/nano manufacturing processes and develop the next generation of semiconductor fabrication techniques. High throughput, low cost, smaller features, high repeatability, and the simplification of the manufacturing processes are all targets that researchers continually strive for. To this day, there are no perfect systems capable of simultaneously achieving all of these targets. For this reason, much research time is spent ...


Refractive Index Chemical Sensing With Noble Metal Nanoparticles, Phillip Blake Dec 2012

Refractive Index Chemical Sensing With Noble Metal Nanoparticles, Phillip Blake

Theses and Dissertations

Chemical sensing is a key component in modern society, especially in engineering applications. Because of their widespread impact, improvements to chemical sensors are a significant area of research. One class of sensors, plasmonic sensors, is being heavily researched because of their ability to detect low levels of analyte in near real time without destroying the analyte. This work studies a new class of plasmonic sensor that utilizes diffractive coupling to improve sensor performance. Specifically, this work outlines the first study of diffractive coupling sensors with typical nanoparticle shapes. Sensitivity of this new class of sensor is directly compared to typical ...


Nanoencapsulated Copper Pthalocyanine As Photodynamic Antimicrobial Chemotherapy, Prathima Arrabelly Jul 2012

Nanoencapsulated Copper Pthalocyanine As Photodynamic Antimicrobial Chemotherapy, Prathima Arrabelly

All Capstone Projects

The growing resistance developed by microbes towards antimicrobial agents has driven our focus on developing alternative treatment modalities such as Photodynamic antimicrobial chemotherapy (PACT). It would be difficult for the microbes to develop resistance towards singlet oxygen generated during the PACT process. Photosensitizers are the vehicles of the transfer and translation of light energy into a type II chemical reaction (singlet oxygen generation) in photodynamic antimicrobial chemotherapy. PACT is proposed as a potential, low cost approach to treatment of locally occurring infection.

Photodynamic inactivation (PDI) of Escherichia coli and Staphylococcus aureus has been studied in cultures treated with photoactivated copper ...