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Articles 1 - 11 of 11
Full-Text Articles in Nanoscience and Nanotechnology
Advanced Iii-V / Si Nano-Scale Transistors And Contacts: Modeling And Analysis, Seung Hyun Park
Advanced Iii-V / Si Nano-Scale Transistors And Contacts: Modeling And Analysis, Seung Hyun Park
Open Access Dissertations
The exponential miniaturization of Si CMOS technology has been a key to the electronics revolution. However, the continuous downscaling of the gate length becomes the biggest challenge to maintain higher speed, lower power, and better electrostatic integrity for each following generation. Hence, novel devices and better channel materials than Si are considered to improve the metal-oxide-semiconductor field-effect transistors (MOSFETs) device performance. III-V compound semiconductors and multi-gate structures are being considered as promising candidates in the next CMOS technology. III-V and Si nano-scale transistors in different architectures are investigated (1) to compare the performance between InGaAs of III-V compound semiconductors and …
Structural Characterization Of Multimetallic Nanoparticles, Vineetha Mukundan
Structural Characterization Of Multimetallic Nanoparticles, Vineetha Mukundan
Open Access Dissertations
Bimetallic and trimetallic alloy nanoparticles have enhanced catalytic activities due to their unique structural properties. Using in situ time-resolved synchrotron based x-ray diffraction, we investigated the structural properties of nanoscale catalysts undergoing various heat treatments. Thermal treatment brings about changes in particle size, morphology, dispersion of metals on support, alloying, surface electronic properties, etc. First, the mechanisms of coalescence and grain growth in PtNiCo nanoparticles supported on planar silica on silicon were examined in detail in the temperature range 400-900°C. The sintering process in PtNiCo nanoparticles was found to be accompanied by lattice contraction and L10chemical ordering. …
Development Of A Static Bioactive Stent Prototype And Dynamic Aneurysm-On-A-Chip(Tm) Model For The Treatment Of Aneurysms, Lisa M. Reece
Development Of A Static Bioactive Stent Prototype And Dynamic Aneurysm-On-A-Chip(Tm) Model For The Treatment Of Aneurysms, Lisa M. Reece
Open Access Dissertations
Aneurysms are pockets of blood that collect outside blood vessel walls forming dilatations and leaving arterial walls very prone to rupture. Current treatments include: (1) clipping, and (2) coil embolization, including stent-assisted coiling. While these procedures can be effective, it would be advantageous to design a biologically active stent, modified with magnetic stent coatings, allowing cells to be manipulated to heal the arterial lining. Further, velocity, pressure, and wall shear stresses aid in the disease development of aneurysmal growth, but the shear force mechanisms effecting wound closure is elusive. Due to these factors, there is a definite need to cultivate …
Silica Nanoparticles As Vehicles For Therapy Delivery In Neurological Injury, Desiree Schenk
Silica Nanoparticles As Vehicles For Therapy Delivery In Neurological Injury, Desiree Schenk
Open Access Dissertations
Acrolein, a very reactive aldehyde, is a culprit in the biochemical cascade after primary, mechanical spinal cord injury (SCI), which leads to the destruction of tissue initially unharmed, referred to as "secondary injury". Additionally, in models of multiple sclerosis (MS) and some clinical research, acrolein levels are significantly increased. This aldehyde overwhelms the natural anti-oxidant system, reacts freely with proteins, and releases during lipid peroxidation (LPO), effectively regenerating its self. Due to its ability to make more copies of itself in the presence of tissue via lipid peroxidation, researchers believe that acrolein plays a role in the increased destruction of …
Role Of Group Ii Metabotropic Glutamate Receptor Subtype 2 (Mglur2) In Appetitive And Consummatory Aspects Of Ethanol Reinforcement, Kyle Allyson Windisch
Role Of Group Ii Metabotropic Glutamate Receptor Subtype 2 (Mglur2) In Appetitive And Consummatory Aspects Of Ethanol Reinforcement, Kyle Allyson Windisch
Open Access Dissertations
Background: Group II metabotropic glutamate receptors (mGluR2/3) are predominately presynaptically located Gi/o coupled receptors that are highly expressed in the cortex, nucleus accumbens, amygdala, and hippocampus. Previous studies suggest that group II mGluRs are involved in regulating ethanol (EtOH) consumption and seeking following extinction (Backstrom and Hyytia, 2005; Kufahl, et al., 2011). The sipper tube model, which allows for procedural separation of seeking and consumption, was used to further clarify the role of mGluR2/3 in EtOH-seeking and consumption. The non-selective group II mGluR agonist LY379268 (LY37) and selective mGluR2 positive allosteric modulator (PAM) BINA were used to determine the …
Nano-Engineered Polymers In Drug Delivery: Potential Approaches For Attenuation Of Secondary Injury After Spinal Cord Trauma, Wen Gao
Open Access Dissertations
Secondary injury elicits a complex series of pathophysiological events after the primary spinal cord trauma and even after its implantation treatment for neural functional recovery. These secondary injuries include an up-regulation of glial cells associated reactive oxygen species, nitrogen species, and reactive astrogliosis, and they can result in various levels of cellular and tissue damage. The inhibition of them has been proved to lead to functional recovery of the spinal cord. In this study, we concentrated on developing polymers and nano-techniques based drug delivery strategies to eliminate these secondary injuries. ^ To maintain and improve the performance of the implants …
Nano-Modification For High Performance Cement Composites With Cellulose Nanocrystals And Carbon Nanotubes, Yizheng Cao
Nano-Modification For High Performance Cement Composites With Cellulose Nanocrystals And Carbon Nanotubes, Yizheng Cao
Open Access Dissertations
One of the new engineering frontiers is the exploration of infrastructure materials with novel combinations of properties that break traditional paradigms. The goal of this study is to utilize two different nano-fibers, cellulose nanocrystals (CNCs) and carbon nanotubes (CNTs) to modify the nanoscale structures of cement composites and thereby improve the performance at the macro-level. This study also evaluates the mechanism behind the modification, since fiber bridging, the most common reinforcing mechanism for fiber-reinforced composites, cannot be simply applied because CNCs are too short to bridge cracks in cement composites. ^ The mechanical tests show an increase in the flexural …
Dynamic Control Of Plasmonic Resonances With Graphene Based Nanostructures, Naresh Kumar Emani
Dynamic Control Of Plasmonic Resonances With Graphene Based Nanostructures, Naresh Kumar Emani
Open Access Dissertations
Light incident on a metallic structure excites collective oscillations of electrons termed as plasmons. These plasmons are useful in control and manipulation of information in nanoscale dimensions and at high operating frequencies. Hence, the field of plasmonics opens up the possibility of developing nanoscale optoelectronic circuitry for computing and sensing applications. One of the challenges in this effort is the lack of tunable plasmonic resonance. Currently, the resonant wavelength of plasmonic structure is fixed by the material and structural parameters. Post-fabrication dynamic control of a plasmonic resonance is rather limited.^ In this thesis we explore the combination of optoelectrical properties …
Hierarchical Cell Fluid Extracellular Matrix Interaction In Cell Microenvironment, Soham Ghosh
Hierarchical Cell Fluid Extracellular Matrix Interaction In Cell Microenvironment, Soham Ghosh
Open Access Dissertations
Hierarchical structural interactions between components of cell microenvironment, the extracellular matrix (ECM), cytoplasm, nucleus and fluid, are important phenomena that decide cell level physiological process and tissue engineering applications. One of those tissue engineering modalities is freezing of biomaterials, important in a wide variety of biomedical applications including cryopreservation and cryosurgeries. In order to design these applications, freezing-induced changes of the cells and tissues and corresponding biophysical mechanisms need to be well understood. Although the effects of freezing on cells in suspension have been extensively studied, the intracellular mechanics of cells embedded in the extracellular matrix (ECM) during freezing are …
Optical Spectroscopy And Langmuir Probe Diagnostics Of Microwave Plasma In Synthesis Of Graphene-Based Nanomaterials, Alfredo D. Tuesta
Optical Spectroscopy And Langmuir Probe Diagnostics Of Microwave Plasma In Synthesis Of Graphene-Based Nanomaterials, Alfredo D. Tuesta
Open Access Dissertations
Along with the revolutionary discovery and development of carbon nanostructures, such as carbon nanotubes and graphitic sheets, has arrived the potential for their application in the fields of medicine, bioscience and engineering due to their exceptional structural, thermal and electrical properties. As roll-to-roll plasma deposition systems begin to provide means for large scale production of these nanodevices, a detailed understanding of the environment responsible for their synthesis is imperative in order to more accurately design and control the growth of carbon nanodevices. To date, the understanding of the chemistry and kinetics that govern the synthesis of carbon nanodevices is only …
Design And Analysis Of Solar Cells By Coupled Electrical - Optical Simulation, Xufeng Wang
Design And Analysis Of Solar Cells By Coupled Electrical - Optical Simulation, Xufeng Wang
Open Access Dissertations
Careful electrical design and optical design are both crucial for achieving high-efficiency solar cells. It is common to link these two aspects serially; the optical design is first done to minimize reflection and maximize light trapping, and then the resulting optical generation rate is input to the electrical simulation. For very high efficiency solar cells that approach the Shockley-Queisser limit, however, electrical and optical transports are tightly coupled in both directions. Photons generated by radiative recombination can be reabsorbed to create additional electron-hole pairs (so-called photon recycling), which decreases losses. A variety of novel photon management schemes are currently being …