Nanoscience and Nanotechnology Commons^™

Functionalization And Length Fractionation Of Single-Wall Carbon Nanotubes, Nina A. Bragg, Jing Pan, Jong Hyun Choi

The Summer Undergraduate Research Fellowship (SURF) Symposium

Single-wall carbon nanotubes (SWCNTs) are a promising material for future biological applications such as imaging and targeted drug delivery. SWCNTs can be made soluble in water through surface functionalization, a priority for their use in biology. By studying the surface chemistry of SWCNTs, various functionalization methods can be accomplished without perturbing their electronic structure. This study probes the use of pyrene derivatives and phospholipids to non-covalently functionalize SWCNTs, maintaining useful surface properties. Phospholipids cross-linked to polyethylene glycol (PEG) or 1-pyrenebutyric acid conjugated to DNA is anchored onto the sidewalls of SWCNTs by hydrophobic interactions or π-stacking. The PEG/DNA portion is …