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University of Nebraska - Lincoln

Alginate

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Full-Text Articles in Nanoscience and Nanotechnology

Role Of Active Nanoliposomes In The Surface And Bulk Mechanical Properties Of Hybrid Hydrogels, R. Kadri, J. Bacharouch, K. Elkhoury, G. Ben Messaoud, C. Kahn, S. Desobry, M. Linder, Ali Tamayol, G. Francius, J.F. Mano, L. Sanchez-Gonzalez, E. Arab-Tehrany Jan 2020

Role Of Active Nanoliposomes In The Surface And Bulk Mechanical Properties Of Hybrid Hydrogels, R. Kadri, J. Bacharouch, K. Elkhoury, G. Ben Messaoud, C. Kahn, S. Desobry, M. Linder, Ali Tamayol, G. Francius, J.F. Mano, L. Sanchez-Gonzalez, E. Arab-Tehrany

Department of Mechanical and Materials Engineering: Faculty Publications

Nanoliposomes are widely used as delivery vehicles for active compounds. Nanoliposomes from rapeseed phospholipids were incorporated into interpenetrating polymer network hydrogels of gelatin methacryloyl and alginate. The multiscale physicochemical properties of the hydrogels are studied both on the surface and through the thickness of the 3D network. The obtained composite hydrogels exhibited strong mechanical properties and a highly porous surface. The blend ratio, as well as the concentration of nanoliposomes, affects the properties of the hydrogels. Nanofunctionalized hydrogels induced keratinocyte growth. These advantageous characteristics may open up many applications of the developed hydrogels in drug delivery and tissue engineering


Rotating-Liquid-Based Hydrogel Bead Generator, Haipeng Zhang, Sangjin Ryu Jan 2020

Rotating-Liquid-Based Hydrogel Bead Generator, Haipeng Zhang, Sangjin Ryu

Department of Mechanical and Materials Engineering: Faculty Publications

Hydrogel beads are widely used in various applications, but producing such beads often requires complicated devices. Instead, we propose an easy-to-adopt, cost effective, open source hydrogel bead generator. This generator consists of two modules. The first module rotates two immiscible liquids in rigid body motion: mineral oil as the continuous phase (CP) liquid on top, and a hydrogel cross-linking (CL) liquid at bottom. The second module injects a hydrogel pre-polymer solution as the dispersed phase (DP) liquid into the rotating CP liquid. As the DP liquid flows out of a syringe needle, its drops are pinched off by the shear …