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Full-Text Articles in Nanoscience and Nanotechnology
Aptamer-Based Voltammetric Biosensing For The Detection Of Codeine And Fentanyl In Sweat And Saliva, Rosa Lashantez Cromartie
Aptamer-Based Voltammetric Biosensing For The Detection Of Codeine And Fentanyl In Sweat And Saliva, Rosa Lashantez Cromartie
FIU Electronic Theses and Dissertations
Despite the many governmental and medicinal restrictions created to combat the opioid epidemic in the United States, opioid abuse and overdose rates continue to rise. The development of an aptamer-based voltammetric sensor and biosensor is described in this dissertation. The aim was to develop a low-cost, sensitive, and specific aptamer-based sensor for on-site, label-free determination of codeine and fentanyl in biological fluids. To do this, the surfaces of screen-printed carbon electrodes (SPCE) were modified with gold nanoparticles (AuNPs), followed by the addition of single-stranded DNA aptamers. These were covalently bound to the electrode surface. Operations of the sensors were collected …
Passive Micromixers And Organic Electrochemical Transistors For Biosensor Applications, Senaka Krishna Kanakamedala
Passive Micromixers And Organic Electrochemical Transistors For Biosensor Applications, Senaka Krishna Kanakamedala
Doctoral Dissertations
Fluid handling at the microscale has greatly affected different fields such as biomedical, pharmaceutical, biochemical engineering and environmental monitoring due to its reduced reagent consumption, portability, high throughput, lower hardware cost and shorter analysis time compared to large devices. The challenges associated with mixing of fluids in microscale enabled us in designing, simulating, fabricating and characterizing various micromixers on silicon and flexible polyester substrates. The mixing efficiency was evaluated by injecting the fluids through the two inlets and collecting the sample at outlet. The images collected from the microscope were analyzed, and the absorbance of the color product at the …
Determination Of Malathion Based On Carbon Nanotubes Modified Electrode Incorporating Acetylcholinesterase, Lu Zhang, Yao-Dong Zhang, Hong-Lan Qi
Determination Of Malathion Based On Carbon Nanotubes Modified Electrode Incorporating Acetylcholinesterase, Lu Zhang, Yao-Dong Zhang, Hong-Lan Qi
Journal of Electrochemistry
A biosensor for determination of organophosphorus pesticide based on the acetylcholinesterase and multi-wall carbon nanotubes modified electrode is fabricated.Under the optimal conditions,the chronoamperometric current at +0.70V(vs.SCE) increased linearly with the concentration of malathion in the range from 6.0×10-10 to 6.0×10-9 mol·L-1 with a detection limit of 1.0×10-10 mol·L-1.The recoveries of malathion in lake water is 97% to 105% determinated by this method.