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- Actin (3)
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- Dry powder inhaler; static charge; asthma; aerodynamic size; oropharyngeal deposition (1)
- MRI Contrast agenta (1)
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Articles 1 - 7 of 7
Full-Text Articles in Nanoscience and Nanotechnology
Effects Of Three Dry Powder Inhalers On Deposition Of Aerosolized Medicine In The Human Oral-Pharyngeal-Laryngeal Regions, Mohammed Ali
Effects Of Three Dry Powder Inhalers On Deposition Of Aerosolized Medicine In The Human Oral-Pharyngeal-Laryngeal Regions, Mohammed Ali
Mohammed Ali
The dry powder inhaler (DPI) is a popular, effective and convenient drug delivery device for inhalation therapy to treat asthma. However, a large quantity (approximately 54%) of inhaled aerosols deposit in the oropharyngeal region. Deposition in this region is undesirable because it provides minimum therapeutic benefits and has adverse localized or systemic side effects. This study reports a method of examining electrostatic charge effects on deposition of three DPI aerosols (Spiriva™ Handihaler, Advair Diskus™, and Pulmicort™ Turbohaler) in a cadaver-based cast of the human oral-pharyngeal-laryngeal (OPL) regions. Experimental aerosols were generated from the three commercially available …
Assembly And Function Of Myosin Ii On Ultraviolet/Ozone Patterned Trimethylchlorosilane Substrates, Hideyo Takatsuki, Madhukar Kolli, Kevin Rice, B. Day, Shinichi Asano, Mashiur Rahman, Yue Zhang, Ryoki Ishikawa, Kazuhiro Kohama, Eric Blough
Assembly And Function Of Myosin Ii On Ultraviolet/Ozone Patterned Trimethylchlorosilane Substrates, Hideyo Takatsuki, Madhukar Kolli, Kevin Rice, B. Day, Shinichi Asano, Mashiur Rahman, Yue Zhang, Ryoki Ishikawa, Kazuhiro Kohama, Eric Blough
B. Scott Day
The study of biomolecular motors represents a rapidly and progressing field of nanobiotechnology. Here, we present a simple method for patterning myosin II on a microstructured surface. Our findings indicate that UV/ozone treatment can be used to alter the hydrophobicity of trimethyl-chloro-silane (TMCS) coated glass surfaces, to alter protein binding, and effectively produce localized motor activity. Taken together, these data suggest that photoreactive patterning may be useful for the selective localization of functional myosin II motor tracks.
Accessibility Of Home Blood Pressure Monitors For Blind And Visually Impaired People, Mark M. Uslan, Darren M. Burton, Thomas E. Wilson, Steven Taylor, Bruce S. Chertow, Jack E. Terry
Accessibility Of Home Blood Pressure Monitors For Blind And Visually Impaired People, Mark M. Uslan, Darren M. Burton, Thomas E. Wilson, Steven Taylor, Bruce S. Chertow, Jack E. Terry
Thomas E. Wilson
Background: The prevalence of hypertension comorbid with diabetes is a significant health care issue. Use of the home blood pressure monitor (HBPM) for aiding in the control of hypertension is noteworthy because of benefits that accrue from following a home measurement regimen. To be usable by blind and visually impaired patients, HBPMs must have speech output to convey all screen information, an easily readable visual display, identifiable controls that are easy to use, and an accessible user manual. Methods: Data on the physical aspects and the features and functions of nine Food and Drug Administration-approved HBPMs (eight of which were …
Bovine Serum Albumin (Bsa) And Cleaved-Bsa Conjugated Ultrasmallgd2o3nanoparticles: Synthesis, Characterization, And Application To Mri Contrast Agents, Md Wasi Ahmad, Cho Rong Kim, Jong Su Baeck, Yongmin Chang, Tae Jeong Kim, Ji Eun Bae, Kwon Seok Chae, Gang Ho Lee
Bovine Serum Albumin (Bsa) And Cleaved-Bsa Conjugated Ultrasmallgd2o3nanoparticles: Synthesis, Characterization, And Application To Mri Contrast Agents, Md Wasi Ahmad, Cho Rong Kim, Jong Su Baeck, Yongmin Chang, Tae Jeong Kim, Ji Eun Bae, Kwon Seok Chae, Gang Ho Lee
Dr. Mohammad Wasi Ahmad (Md Wasi Ahmad)
No abstract provided.
Assembly And Function Of Myosin Ii On Ultraviolet/Ozone Patterned Trimethylchlorosilane Substrates, Hideyo Takatsuki, Madhukar Kolli, Kevin Rice, B. Day, Shinichi Asano, Mashiur Rahman, Yue Zhang, Ryoki Ishikawa, Kazuhiro Kohama, Eric Blough
Assembly And Function Of Myosin Ii On Ultraviolet/Ozone Patterned Trimethylchlorosilane Substrates, Hideyo Takatsuki, Madhukar Kolli, Kevin Rice, B. Day, Shinichi Asano, Mashiur Rahman, Yue Zhang, Ryoki Ishikawa, Kazuhiro Kohama, Eric Blough
Kevin M Rice
The study of biomolecular motors represents a rapidly and progressing field of nanobiotechnology. Here, we present a simple method for patterning myosin II on a microstructured surface. Our findings indicate that UV/ozone treatment can be used to alter the hydrophobicity of trimethyl-chloro-silane (TMCS) coated glass surfaces, to alter protein binding, and effectively produce localized motor activity. Taken together, these data suggest that photoreactive patterning may be useful for the selective localization of functional myosin II motor tracks.
Assembly And Function Of Myosin Ii On Ultraviolet/Ozone Patterned Trimethylchlorosilane Substrates, Hideyo Takatsuki, Madhukar Kolli, Kevin Rice, B. Day, Shinichi Asano, Mashiur Rahman, Yue Zhang, Ryoki Ishikawa, Kazuhiro Kohama, Eric Blough
Assembly And Function Of Myosin Ii On Ultraviolet/Ozone Patterned Trimethylchlorosilane Substrates, Hideyo Takatsuki, Madhukar Kolli, Kevin Rice, B. Day, Shinichi Asano, Mashiur Rahman, Yue Zhang, Ryoki Ishikawa, Kazuhiro Kohama, Eric Blough
Eric Blough
The study of biomolecular motors represents a rapidly and progressing field of nanobiotechnology. Here, we present a simple method for patterning myosin II on a microstructured surface. Our findings indicate that UV/ozone treatment can be used to alter the hydrophobicity of trimethyl-chloro-silane (TMCS) coated glass surfaces, to alter protein binding, and effectively produce localized motor activity. Taken together, these data suggest that photoreactive patterning may be useful for the selective localization of functional myosin II motor tracks.
Sub-Wavelength Plasmonic Readout For Direct Linear Analysis Of Optically Tagged Dna, Jonathan Varsanik, William Teynor, John Leblanc, Heather Clark, Jeffrey Krogmeier, Tian Yang, Jonathan Bernstein
Sub-Wavelength Plasmonic Readout For Direct Linear Analysis Of Optically Tagged Dna, Jonathan Varsanik, William Teynor, John Leblanc, Heather Clark, Jeffrey Krogmeier, Tian Yang, Jonathan Bernstein
Heather Clark
This work describes the development and fabrication of a novel nanofluidic flow-through sensing chip that utilizes a plasmonic resonator to excite fluorescent tags with sub-wavelength resolution. We cover the design of the microfluidic chip and simulation of the plasmonic resonator using Finite Difference Time Domain (FDTD) software. The fabrication methods are presented, with testing procedures and preliminary results. This research is aimed at improving the resolution limits of the Direct Linear Analysis (DLA) technique developed by US Genomics. In DLA, intercalating dyes which tag a specific 8 base-pair sequence are inserted in a DNA sample. This sample is pumped though …