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Applied Mechanics Commons

Open Access. Powered by Scholars. Published by Universities.®

2005

Microvalve

Articles 1 - 1 of 1

Full-Text Articles in Applied Mechanics

Self-Actuated, Thermo-Responsive Hydrogel Valves For Lab On A Chip, Jing Wang, Zongyuan Chen, Michael Mauk, Kuang-Sheng Hong, Mengyan Li, Shu Yang, Haim H. Bau Jun 2005

Self-Actuated, Thermo-Responsive Hydrogel Valves For Lab On A Chip, Jing Wang, Zongyuan Chen, Michael Mauk, Kuang-Sheng Hong, Mengyan Li, Shu Yang, Haim H. Bau

Departmental Papers (MEAM)

An easy to fabricate, thermally-actuated, self-regulated hydrogel valve for flow control in pneumatically driven, microfluidic systems is described. This microvalve takes advantage of the properties of the hydrogel, poly(N-isopropylacrylamide), as well as the aqueous fluid itself to realize flow control. The valve was designed for use in a diagnostic system fabricated with polycarbonate and aimed at the detection of pathogens in oral fluids at the location of the sample collection. The paper describes the construction and characterization of the hydrogel valves and their application for flow control, sample and reagent metering, sample distribution into multiple analysis paths, and the ...