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Full-Text Articles in Mechanical Engineering
Design And Validation Of An In Vivo Long-Term Attachment Capsule Robot, Wanchuan Xie
Design And Validation Of An In Vivo Long-Term Attachment Capsule Robot, Wanchuan Xie
Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research
The invention of capsule endoscopy (CE) made the non-invasive monitoring of the entire small bowel possible and became the primary means for diagnosing small bowel pathology. In the last decade, capsule robots have been transformed from diagnostic devices into a widely studied biomedical platform with the potential for active locomotion, drug delivery and therapeutic capabilities. To perform accurate on-site drug release and therapy, it is necessary for a capsule robot to be able to attach to the intestinal tissue and maintain its position long-term. Design challenges derive from the task of long-term mucosal adhesion which requires firm, quick-response attachment without …
Biomechanical Modeling For Lung Tumor Motion Prediction During Brachytherapy And Radiotherapy, Zahra Shirzadi
Biomechanical Modeling For Lung Tumor Motion Prediction During Brachytherapy And Radiotherapy, Zahra Shirzadi
Electronic Thesis and Dissertation Repository
A novel technique is proposed to develop a biomechanical model for estimating lung’s tumor position as a function of respiration cycle time. Continuous tumor motion is a major challenge in lung cancer treatment techniques where the tumor needs to be targeted; e.g. in external beam radiotherapy and brachytherapy. If not accounted for, this motion leads to areas of radiation over and/or under dosage for normal tissue and tumors. In this thesis, biomechanical models were developed for lung tumor motion predication in two distinct cases of lung brachytherapy and lung external beam radiotherapy. The lung and other relevant surrounding organs geometries, …