Mechanical Engineering Commons^™

Lab-On-A-Chip For Oral Cancer Screening And Diagnosis, Barry L. Ziober, Michael G. Mauk, Erica M. Falls, Zongyuan Chen, Amy F. Ziober, Haim H. Bau

Departmental Papers (MEAM)

Oral squamous cell carcinoma (OSCC) is a disfiguring and deadly cancer. Despite advances in therapy, many patients continue to face a poor prognosis. Early detection is an important factor in determining the survival of patients with OSCC. No accurate, cost-efficient, and reproducible method exists to screen patients for OSCC. As a result, many patients are diagnosed at advanced stages of the disease. Early detection would identify patients, facilitating timely treatment and close monitoring. Mass screening requires a rapid oral cancer diagnostic test that can be used in a clinical setting. Current diagnostic techniques for OSCC require modern laboratory facilities, sophisticated ...