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Theoretical And Experimental Evaluation Of Cardiac State Utilizing Indicator Dilution Methods For Nonuniform Ventricular Mixing, Stanley Myron Welland

Dissertations

This research is directed toward the development and application of a new approach to the evaluation of cardiac work to diagnose cardiac state. A procedure has been developed for calculating the work performed on the fluid by the left ventricle during the heartbeat. The procedure involves the continuous direct measurement of ventricular fluid mixture temperature during and following the controlled injection, through a catheter, of a known volume of cold saline into the left ventricle. The measured mixture temperatures are used to calculate continuous ventricular volumes during the systolic and diastolic functions of the heartbeat. Plotting measured ventricular pressure versus …