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Full-Text Articles in Mechanical Engineering
Fiber Optic Bandage, Logan Mcneil, Cameron Pilkey, Brittani Erwin, Adam Wojnar
Fiber Optic Bandage, Logan Mcneil, Cameron Pilkey, Brittani Erwin, Adam Wojnar
Faculty Publications and Other Works -- Biomedical and Diagnostic Sciences
The purpose of this document is to show the report for the Fiber optic device formulated through the biomedical engineering department with a senior design group. A growing issue in medical technology is open wound care. Particularly prevalent in diabetics, open wound care is expensive and time consuming. Certain wavelengths of light have not only shown to have germicidal properties, but also allow cell growth and regeneration. The following design was founded around these ideas, and an initial design was developed. The design centered around using fiber optics as a means of replacing a wet bandage in a normal wound …
A Shooting Algorithm For Complex Immunodominance Control Problems, Xiaopeng Zhao, R Yang, M Zhang
A Shooting Algorithm For Complex Immunodominance Control Problems, Xiaopeng Zhao, R Yang, M Zhang
Faculty Publications and Other Works -- Mechanical, Aerospace and Biomedical Engineering
Although T cells are able to recognize a wide variety of target peptides, they are often strongly focused on a few of the peptides and leave the rest of them unattended. This phenomenon of strongly biased immune response is known as immunodominance. Mathematically, an immunodominance problem can be formulated using optimal control principles as a two-point boundary-value problem. The solution of this problem is challenging especially when the control variables are bounded. In this work, we develop a numerical algorithm based on the shooting technique for bounded optimal control problems. The algorithm is applied to a group of immunodominance problems. …