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Full-Text Articles in Mechanical Engineering
A New Microfluidic Device For Complete, Continuous Separation Of Microparticles, Liang-Liang Fan, Xu-Kun He, Yu Han, Li Du, Liang Zhao, Jiang Zhe
A New Microfluidic Device For Complete, Continuous Separation Of Microparticles, Liang-Liang Fan, Xu-Kun He, Yu Han, Li Du, Liang Zhao, Jiang Zhe
Dr. Jiang Zhe
A microchannel with symmetric sharp corners is reported for particle separation, based on the inter-play between the inertial lift force and the centrifugal force induced by sharp corners. At an appropriate flow rate, the centrifugal force is larger than the inertial lift force on large particles, while the inertial lift force is dominant on small particles. Hence large particles are centrifuged to the center, while small par-ticles are focused at side streams, achieving complete particle separation. The device requires no sheath flow, avoiding the dilution of analyte sample and complex operation, and can be potentially used for many lab-on-a-chip applications.
Passive Continuous Particle Focusing In A Microchannel With Symmetric Sharp Corner Structures, Liang-Liang Fan, Liang Zhao, Xu-Kun He, Hand Yu, Qing-Yu Wei, Jiang Zhe
Passive Continuous Particle Focusing In A Microchannel With Symmetric Sharp Corner Structures, Liang-Liang Fan, Liang Zhao, Xu-Kun He, Hand Yu, Qing-Yu Wei, Jiang Zhe
Dr. Jiang Zhe
We report a continuous passive particle focusing method using a novel microchannel with symmetric sharp corners which induce curved streamlines and large centrifugal force on particles. At appropriate flow rate, the centrifugal force generated on particles exceeds the inertial lift force; particles driven by the centrifugal force migrate toward the center of the microchannel, achieving continuous particle focus-ing. With simple structure and operation, this method can be potentially used in particle focusing and ex-traction processes in a variety of lab-on-a chip applications.
A Rapid Magnetic Particle Driven Micromixer, Yiou Wang, Jiang Zhe, Benjamin Chung, Prashanta Dutta
A Rapid Magnetic Particle Driven Micromixer, Yiou Wang, Jiang Zhe, Benjamin Chung, Prashanta Dutta
Dr. Jiang Zhe
Performances of a magnetic particle driven micromixer are predicted numerically. This micromixer takes advantages of mixing enhancements induced by alternating actuation of magnetic particles suspended in the fluid. Effects of magnetic actuation force, switching frequency and channel’s lateral dimension have been investigated. Numerical results show that the magnetic particle actuation at an appropriate frequency causes effective mixing and the optimum switching frequency depends on the channel’s lateral dimension and the applied magnetic force. The maximum efficiency is obtained at a relatively high operating frequency for large magnetic actuation forces and narrow microchannels. If the magnetic particles are actuated with a …