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Full-Text Articles in Mechanical Engineering
Microfluidic Particle And Cell Manipulation Using Reservoir-Based Dielectrophoresis, Saurin Patel
Microfluidic Particle And Cell Manipulation Using Reservoir-Based Dielectrophoresis, Saurin Patel
All Dissertations
Controlled manipulation of synthetic particles and biological cells from a complex mixture is important to a wide range of applications in biology, environmental monitoring, and pharmaceutical industry. In the past two decades microfluidics has evolved to be a very useful tool for particle and cell manipulations in miniaturized devices. A variety of force fields have been demonstrated to control particle and cell motions in microfluidic devices, among which electrokinetic techniques are most often used. However, to date, studies of electrokinetic transport phenomena have been primarily confined within the area of microchannels. Very few works have addressed the electrokinetic particle motion …
Study Of Cell Viability During Laser Direct Writing Of Cell-Alginate Suspension, Hemanth Gudapati
Study Of Cell Viability During Laser Direct Writing Of Cell-Alginate Suspension, Hemanth Gudapati
All Theses
Laser-assisted cell printing, developed based on Matrix-assisted pulsed-laser evaporation direct-write (MAPLE DW), a typical LIFT (laser-induced forward transfer) practice, has been emerging as one of the most promising biofabrication techniques. Alginate, particularly sodium alginate, is extensively used as the constituent of bioink in laser-assisted cell printing. However, thus far, studies investigating the effect of alginate gelation on cell viability in laser-assisted cell printing are lacking. The objective of this study is to investigate the effects of gelation, gelation time, sodium alginate concentration, and the effect of operating conditions such as the laser fluence on post-transfer cell viability during laser-assisted cell …