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Articles 1 - 28 of 28
Full-Text Articles in Mechanical Engineering
Mitochondrial Dynamics And Respiration Within Cells With Increased Open Pore Cytoskeletal Meshes, David H. Jang, Sarah C. Seeger, Martha E. Grady, Frances S. Shofer, David M. Eckmann
Mitochondrial Dynamics And Respiration Within Cells With Increased Open Pore Cytoskeletal Meshes, David H. Jang, Sarah C. Seeger, Martha E. Grady, Frances S. Shofer, David M. Eckmann
Mechanical Engineering Faculty Publications
The cytoskeletal architecture directly affects the morphology, motility, and tensional homeostasis of the cell. In addition, the cytoskeleton is important for mitosis, intracellular traffic, organelle motility, and even cellular respiration. The organelle responsible for a majority of the energy conversion for the cell, the mitochondrion, has a dependence on the cytoskeleton for mobility and function. In previous studies, we established that cytoskeletal inhibitors altered the movement of the mitochondria, their morphology, and their respiration in human dermal fibroblasts. Here, we use this protocol to investigate applicability of power law diffusion to describe mitochondrial locomotion, assessment of rates of fission and …
The Vibe, Sarah P. Douglass
The Vibe, Sarah P. Douglass
Capstones
The Vibe is a long-form narrative about where tech is taking the female orgasm. The piece concludes that physiological research is a required next step when creating the climax of the future.
http://sarahpdouglass.com
Characterizing Anisotropy In Fibrous Soft Materials By Mr Elastography Of Slow And Fast Shear Waves, John Larson Schmidt
Characterizing Anisotropy In Fibrous Soft Materials By Mr Elastography Of Slow And Fast Shear Waves, John Larson Schmidt
McKelvey School of Engineering Theses & Dissertations
The general objective of this work was to develop experimental methods based on magnetic resonance elastography (MRE) to characterize fibrous soft materials. Mathematical models of tissue biomechanics capable of predicting injury, such as traumatic brain injury (TBI), are of great interest and potential. However, the accuracy of predictions from such models depends on accuracy of the underlying material parameters. This dissertation describes work toward three aims. First, experimental methods were designed to characterize fibrous materials based on a transversely isotropic material model. Second, these methods are applied to characterize the anisotropic properties of white matter brain tissue ex vivo. Third, …
Habitat Use Of Blacktip Sharks (Carcharhinus Limbatus) At Fishing Piers, Kelsey L. Spencer
Habitat Use Of Blacktip Sharks (Carcharhinus Limbatus) At Fishing Piers, Kelsey L. Spencer
Electronic Theses and Dissertations
Blacktip sharks (Carcharhinus limbatus) can be observed near fishing piers throughout the summer along the northeast coast of South Carolina. These piers attract and support a wide variety of potential prey and sharks are able to forage on fishers’ discards with minimal energetic cost. I tagged 12 blacktip sharks with acoustic transmitters, monitored piers with acoustic receivers, and conducted pier-creel surveys to determine the habitat use of blacktip sharks at fishing piers, factors that influenced residence time and presence/absence at piers, and any cyclical patterns in visits to piers. Data were analyzed with pier association indices (PAI), mixed models, and …
Rehabilitating Asymmetric Gait Using Asymmetry, Tyagi Ramakrishnan
Rehabilitating Asymmetric Gait Using Asymmetry, Tyagi Ramakrishnan
USF Tampa Graduate Theses and Dissertations
Human gait is a complex process that involves the coordination of the central nervous and muscular systems. A disruption to the either system results in the impairment of a person’s ability to walk. Impairments can be caused by neurological disorders such as stroke and physical conditions like amputation. There is not a standardized method to quantitatively assess the gait asymmetry of affected subjects. The purpose of this research is to understand the fundamental aspects of asymmetrical effects on the human body and improve rehabilitation techniques and devices. This research takes an interdisciplinary approach to address the limitations with current rehabilitation …
Effects Of Malformed Or Absent Valves To Lymphatic Fluid Transport And Lymphedema In Vivo In Mice, Akshay S. Pujari
Effects Of Malformed Or Absent Valves To Lymphatic Fluid Transport And Lymphedema In Vivo In Mice, Akshay S. Pujari
Masters Theses
Lymph is primarily composed of fluid and proteins from the blood circulatory system that drain into the space surrounding cells, interstitial space. From the interstitial space, the fluid enters and circulates in the lymphatic system until it is delivered into the venous system. In contrast to the blood circulatory system, the lymphatic system lacks a central pumping organ dictating the predominant driving pressure and velocity of lymph. Transport of lymph via capillaries, pre-collecting and collecting lymphatic vessels relies on the synergy between pressure gradients, local tissue motion, valves and lymphatic vessel contractility. The direction of lymph transport is regulated by …
Bacterial Motility And Its Role In Biofilm Formation, Clayton J. Culp, Arezoo M. Ardekani, Adib Ahmadzadegan
Bacterial Motility And Its Role In Biofilm Formation, Clayton J. Culp, Arezoo M. Ardekani, Adib Ahmadzadegan
The Summer Undergraduate Research Fellowship (SURF) Symposium
Bacterial biofilms are known to cause millions of dollars in damage in the medical industry per year via infection of central venous catheters, urinary catheters, and mechanical heart valves. Unfortunately, there are some characteristics of biofilm formation that are yet to be fully understood. Recently much work has been done to investigate the motility characteristics of bacteria with hopes of better understanding the phenomena of biofilm formation. Still, one of the least understood stages is bacterial attachment or adhesion, a process designed to anchor bacteria in an advantageous environment. Providing a better understanding of bacterial motility near solid interfaces will …
Optimization Of Prosthetic Hands: Utilizing Modularity To Improve Grip Force, Grasp, And Versatility, Jordan William Harris
Optimization Of Prosthetic Hands: Utilizing Modularity To Improve Grip Force, Grasp, And Versatility, Jordan William Harris
UNLV Theses, Dissertations, Professional Papers, and Capstones
It has been demonstrated that although many varieties of upper limb prosthetics exist, commercially available prosthetics are outdated and unsatisfactory. Ineffectiveness and limitations have led to some prosthesis wearers having to own multiple devices, whereas others have given up on them entirely. Even though ample research has been conducted to design and test new hand designs, the industry appears to rest in an overall stagnated state.
It was proposed here, that one problem with prosthetic research is an excess of variables involved in testing, and therefore the improper application of the scientific method. It seems that each time a research …
An Array Of Circular Dielectrophoresis Traps To Separate And Charaterize Individual Microparticles From Population, Hwangjae Lee
An Array Of Circular Dielectrophoresis Traps To Separate And Charaterize Individual Microparticles From Population, Hwangjae Lee
Theses and Dissertations
Dielectrophoretic traps have been broadly studied in light of their many advantages of high controllability, ease of operation, and high efficiency. In the previous studies, however, it was challenging to count captured particles or required work to capture particles. In the thesis, an array of circular dielectrophoresis (DEP) traps was developed and tested to manipulate population of microparticles in single particle level. The circular DEP traps enable more precise control of the force field than conventionally used interdigitated electrodes due to its omnidirectional and symmetric properties. The location of the captured microparticle inside the trap was confirmed by both of …
A Magnetic Resonance Compatible Knee Extension Ergometer, Youssef Jaber
A Magnetic Resonance Compatible Knee Extension Ergometer, Youssef Jaber
Masters Theses
The product of this thesis aims to enable the study of the biochemical and physical dynamics of the lower limbs at high levels of muscle tension and fast contraction speeds. This is accomplished in part by a magnetic resonance (MR) compatible ergometer designed to apply a load as a torque of up to 420 Nm acting against knee extension at speeds as high as 4.7 rad/s. The system can also be adapted to apply the load as a force of up to 1200 N acting against full leg extension. The ergometer is designed to enable the use of magnetic resonance …
Solvent Based 3d Printing Of Biopolymer/Bioactive Glass Composite And Hydrogel For Tissue Engineering Applications, Krishna Kolan, Yong Liu, Jakeb Baldridge, Caroline Murphy, Julie A. Semon, D. E. Day, Ming-Chuan Leu
Solvent Based 3d Printing Of Biopolymer/Bioactive Glass Composite And Hydrogel For Tissue Engineering Applications, Krishna Kolan, Yong Liu, Jakeb Baldridge, Caroline Murphy, Julie A. Semon, D. E. Day, Ming-Chuan Leu
Biological Sciences Faculty Research & Creative Works
Three-dimensional (3D) bioprinting is an emerging technology in which scaffolding materials and cell-laden hydrogels may be deposited in a pre-determined fashion to create 3D porous constructs. A major challenge in 3D bioprinting is the slow degradation of melt deposited biopolymer. In this paper, we describe a new method for printing poly-caprolactone (PCL)/bioactive borate glass composite as a scaffolding material and Pluronic F127 hydrogel as a cell suspension medium. Bioactive borate glass was added to a mixture of PCL and organic solvent to make an extrudable paste using one syringe while hydrogel was extruded and deposited in between the PCL/borate glass …
Marine Biomass Analyzer, Kai Jay Staal, Brian Paris, Tyler Cottle
Marine Biomass Analyzer, Kai Jay Staal, Brian Paris, Tyler Cottle
Mechanical Engineering
This report documents the design, fabrication, and testing for a marine biomass analyzer. The goal of the project and constructed system was to determine the validity and efficacy of a process that could flatten benthic macrofauna to a consistent thickness such that a biomass for the collected sample could be accurately determined. The system that was built and tested consists of a drive train that turns a mill subassembly where the organisms are flattened, supply and collection spools that hold the white fabric and clear film used to capture the organisms, a collection zone where the sample is injected, and …
Marine Gastrobot Final Design Report, Wesley B. Williams, Eric Kane Dreischerf, Tommy Nicholas Yath
Marine Gastrobot Final Design Report, Wesley B. Williams, Eric Kane Dreischerf, Tommy Nicholas Yath
Mechanical Engineering
The Marine Gastrobot sponsored by Dr. Christopher Kitts of the Cal Poly Center for Applications in Biotechnology was a research and development effort intended to explore the use of microbial fuel cell technology as a power source for underwater robots. Our team Ocean Locomotion succeeded in developing a first iteration of an underwater robotic platform suitable for microbial fuel cell integration. The primary feature of the design is its sinusoidal fin propulsion intended for benthic exploration with limited risk of entanglement. During the course of development, Ocean Locomotion explored the use of low power actuation methods and determined their limited …
Vrshape: A Virtual Reality Tool For Shaping Movement Compensation, Matthew Hale Foreman
Vrshape: A Virtual Reality Tool For Shaping Movement Compensation, Matthew Hale Foreman
Arts & Sciences Electronic Theses and Dissertations
The majority of persons living with chronic stroke experience some form of upper extremity motor impairment that affects their functional movement, performance of meaningful activities, and participation in the flow of daily life. Stroke survivors often compensate for these impairments by adapting their movement patterns to incorporate additional degrees of freedom at new joints and body segments. One of the most common compensatory movements is the recruitment of excessive trunk flexion when reaching with the affected upper extremity. Long-term use of these compensations may lead to suboptimal motor recovery and chronic pain or injury due to overuse. Rehabilitation focuses on …
The Aerodynamic Effects On Flight Patterns And The Evolutionary Changes In Pterosaurs, Johnathan D. Talik
The Aerodynamic Effects On Flight Patterns And The Evolutionary Changes In Pterosaurs, Johnathan D. Talik
Undergraduate Research & Mentoring Program
Early pterosaurs were the first vertebrates to achieve powered flight, and remained small-to-medium sized from the Triassic Period to the end of the Jurassic Period. During that interval, lasting from 210 million years ago to 66 million years ago, pterosaurs underwent a notable changes at the end of the Jurassic Period and through the Cretaceous Period. They were abruptly replaced by much larger forms, characterized by great size and peculiar head ornamentation, among other unique and notable morphological features. While many different explanations theorize why and how the features of the pterosaurs changed over the Cretaceous Period, the aerodynamic influences …
An Electrochemical Analysis Of Fretting Corrosion In Metal-On-Metal Hip Implants Subjected To High Impaction Loads, Joe Morin, Timothy L. Norman, Thomas K. Fehring
An Electrochemical Analysis Of Fretting Corrosion In Metal-On-Metal Hip Implants Subjected To High Impaction Loads, Joe Morin, Timothy L. Norman, Thomas K. Fehring
The Research and Scholarship Symposium (2013-2019)
The metal-on-metal total hip arthroplasty, a procedure where the hip joint is replaced by a femoral prosthesis with a metal femoral head and a metal socket, has been a popular option for patients requiring a hip joint replacement. Metal on metal hip implants have been a successful implant design until recently where there has been an increased number of failures of this type of implant due to fretting corrosion, believed to be caused from the use of large femoral heads. Fretting corrosion in hip implants results from cyclic micromotion at the taper-trunnion interface; this interface motion removes the protective oxidation …
3d Printing Of Biodegradable Scaffolds For Tissue Engineering Applications, Joe Morin, Michael Pickett, Amy Abraham, Tiera Martinelli
3d Printing Of Biodegradable Scaffolds For Tissue Engineering Applications, Joe Morin, Michael Pickett, Amy Abraham, Tiera Martinelli
The Research and Scholarship Symposium (2013-2019)
With the recent improvements in three dimensional (3D) printing technologies, the potential for tissue engineering and regenerative medicine have significantly improved. One key idea in tissue engineering is to specifically design scaffolds to aid in the healing process by being incorporated into the body’s own tissue. The overall goal of this project is to investigate 3D printable scaffold design to access suitability for tissue replacement. This was accomplished by analyzing the effect of the material used to create the scaffolds, pore size, and pore shape on mechanical stiffness and cell culturability. Based on published literature, it was determined that, depending …
Experimental Evaluation Of Cooling Effectiveness And Water Conservation In A Poultry House Using Flow Blurring® Atomizers, Rafael M. Rodriguez
Experimental Evaluation Of Cooling Effectiveness And Water Conservation In A Poultry House Using Flow Blurring® Atomizers, Rafael M. Rodriguez
USF Tampa Graduate Theses and Dissertations
Increases in population as well as economic improvements in developing countries are generating a larger demand for animal protein products. Current animal growth processes inherently, require the use of water in many forms throughout the growth cycle. Water is the most important natural resource on earth to sustain life, and in many developing countries is a scarce resource that must be used wisely. Studies have revealed that poultry growth can take place with less water consumption, when compared with other sources of animal protein (e.g., cattle, pork). In this research, an evaporative Flow Blurring® cooling system was considered as …
Constraints On Acoustic Signaling Among Birds Breeding In Secondary Cavities: The Effects Of Weather, Cavity Material, And Noise On Sound Propagation, John P. Swaddle, Caitlin R. Kight, Saji Perera, Eduardo Davila-Reyes, Shena Sikora
Constraints On Acoustic Signaling Among Birds Breeding In Secondary Cavities: The Effects Of Weather, Cavity Material, And Noise On Sound Propagation, John P. Swaddle, Caitlin R. Kight, Saji Perera, Eduardo Davila-Reyes, Shena Sikora
John Swaddle
Increasing evidence suggests that anthropogenic noise from urbanization affects animal acoustic communication. We investigated whether the begging calls of nestling Eastern Bluebirds (Sialia sialis) varied along a disturbance gradient of ambient noise. Contrary to our prediction and the results of a previous study of nestling Tree Swallows (Tachycineta bicolor), we found that nestling Eastern Bluebirds did not increase the amplitude or structural characteristics—including frequency, rate, and duration—of their vocalizations in response to ambient noise. However, we found that prevalent temperature and humidity conditions attenuated begging calls. Specifically, in warmer, more humid weather, vocalizations of nestling Eastern …
Soft-Tissue Artifact Compensation For Electromagnetic Motion Capture, George T. Dickinson, Steven K. Charles
Soft-Tissue Artifact Compensation For Electromagnetic Motion Capture, George T. Dickinson, Steven K. Charles
Biomedical Engineering Western Regional Conference
This purpose of this study is to develop a soft-tissue artifact compensation algorithm for the upper arm using electromagnetic motion capture systems that can be implemented in a wide range of applications. This study focuses on compensation of humeral axial rotation and forearm axial rotation.
Portable, Powerless Automation Of Valve Actuation For Microfluidic Large-Scale Integration Technology, Andrew Schmidt Mr., Matt Fitzgerald Mr., Emre Araci Mr., Connor Mcloughlin Mr.
Portable, Powerless Automation Of Valve Actuation For Microfluidic Large-Scale Integration Technology, Andrew Schmidt Mr., Matt Fitzgerald Mr., Emre Araci Mr., Connor Mcloughlin Mr.
Biomedical Engineering Western Regional Conference
Portable, powerless automation of valve actuation for microfluidic large-scale integration technology
Biophysical Tools To Study Cellular Mechanotransduction, Ismeel Muhamed, Farhan Chowdhury, Venkat Maruthamuthu
Biophysical Tools To Study Cellular Mechanotransduction, Ismeel Muhamed, Farhan Chowdhury, Venkat Maruthamuthu
Mechanical & Aerospace Engineering Faculty Publications
The cell membrane is the interface that volumetrically isolates cellular components from the cell's environment. Proteins embedded within and on the membrane have varied biological functions: reception of external biochemical signals, as membrane channels, amplification and regulation of chemical signals through secondary messenger molecules, controlled exocytosis, endocytosis, phagocytosis, organized recruitment and sequestration of cytosolic complex proteins, cell division processes, organization of the cytoskeleton and more. The membrane's bioelectrical role is enabled by the physiologically controlled release and accumulation of electrochemical potential modulating molecules across the membrane through specialized ion channels (e.g., Na⁺, Ca2+, K⁺ channels). …
Fourth-Generation Fan Assessment Numeration System (Fans) Design And Performance Specifications, Michael P. Sama, George B. Day, Laura M. Pepple, Richard S. Gates
Fourth-Generation Fan Assessment Numeration System (Fans) Design And Performance Specifications, Michael P. Sama, George B. Day, Laura M. Pepple, Richard S. Gates
Biosystems and Agricultural Engineering Faculty Publications
The Fan Assessment Numeration System (FANS) is a measurement device for generating ventilation fan performance curves. Three different-sized FANS currently exist for assessing ventilation fans commonly used in poultry and livestock housing systems. All FANS consist of an array of anemometers inside an aluminum shroud that traverse the inlet or outlet of a ventilation fan. The FANS design has been updated several times since its inception and is currently in its fourth-generation (G4). The current design iteration (FANS-G4) is reported in this article with an emphasis on the hardware and software control, data acquisition systems, and operational reliability. Six FANS-G4 …
Biomechanics Of Concussion: The Importance Of Neck Tension, Ron Jadischke
Biomechanics Of Concussion: The Importance Of Neck Tension, Ron Jadischke
Wayne State University Dissertations
Linear and angular velocity and acceleration of the head are typically correlated to concussion. Despite improvements in helmet performance to reduce accelerations, a corresponding reduction in the incidence of concussion has not occurred (National Football League [NFL] 1996 – present).
There is compelling research that forces on and deformation to the brain stem are related to concussion. The brain stem is the center of control for respiration, blood pressure and heart rate and is the root of most cranial nerves. Injury to the brain stem is consistent with most symptoms of concussion reported in the National Football League and the …
Development Of A Finite Element Pelvis And Lower Extremity Model With Growth Plates For Pediatric Pedestrian Protection, Ming Shen
Wayne State University Dissertations
Finite element (FE) model is a useful tool frequently used for investigating the injury mechanisms and designing protection countermeasures. At present, no 10 years old (YO) pedestrian FE model has been developed from appropriate anthropometries and validated against limitedly available impact response data. A 10 YO child FE pelvis and lower extremities (PLEX) model was established to fill the gap of lacking such models in this age group. The baseline model was validated against available pediatric postmortem human subjects (PMHS) test data and additional scaled adult data, then the PLEX model was integrated to build a whole-body FE model representing …
3d Bioprinting Of Stem Cells And Polymer/Bioactive Glass Composite Scaffolds For Bone Tissue Engineering, Caroline Murphy, Krishna Kolan, Wenbin Li, Julie A. Semon, D. E. Day, Ming-Chuan Leu
3d Bioprinting Of Stem Cells And Polymer/Bioactive Glass Composite Scaffolds For Bone Tissue Engineering, Caroline Murphy, Krishna Kolan, Wenbin Li, Julie A. Semon, D. E. Day, Ming-Chuan Leu
Biological Sciences Faculty Research & Creative Works
A major limitation of using synthetic scaffolds in tissue engineering applications is insufficient angiogenesis in scaffold interior. Bioactive borate glasses have been shown to promote angiogenesis. There is a need to investigate the biofabrication of polymer composites by incorporating borate glass to increase the angiogenic capacity of the fabri-cated scaffolds. In this study, we investigated the bioprinting of human adipose stem cells (ASCs) with a polycaprolac-tone (PCL)/bioactive borate glass composite. Borate glass at the concentration of 10 to 50 weight %, was added to a mixture of PCL and organic solvent to make an extrudable paste. ASCs suspended in Matrigel …
Chocolate Bar Wrapping Machine, Austin M. Hoff, Daniel R. Trepke, Caleb B. Krichbuam
Chocolate Bar Wrapping Machine, Austin M. Hoff, Daniel R. Trepke, Caleb B. Krichbuam
Williams Honors College, Honors Research Projects
Gilbert Chocolates has proposed to manufacture a machine to wrap chocolate bars. This machine is intended to replace two people wrapping the chocolate bars by hand, which is a time consuming method. This is especially apparent between October and January when the workers are working long hours in preparation for the Christmas rush of customers. Currently wrapping a bar takes about a minute and Gilbert Chocolates wants this time reduced down to 20-30 seconds. The budget for this project is set at $1000, and is being funded by the company. This machine needs to fit in a cubic foot of …
Behavioral Responses Of Sub-Adult Atlantic Sturgeon (Acipenser Oxyrinchus Oxyrinchus) To Electromagnetic And Magnetic Fields Under Laboratory Conditions, Andrew Mcintyre Iii
Behavioral Responses Of Sub-Adult Atlantic Sturgeon (Acipenser Oxyrinchus Oxyrinchus) To Electromagnetic And Magnetic Fields Under Laboratory Conditions, Andrew Mcintyre Iii
Theses and Dissertations
Electromagnetic fields (EMF) produced by high voltage (HV), submarine transmission cables leading from offshore wind energy generation facilities could affect foraging or migratory behaviors of electro-receptive fishes, including endangered Atlantic Sturgeon. However, no published studies have quantitatively evaluated the possible behavioral effects of EMF exposure on sturgeon during residence in coastal waters. This study evaluated behavioral responses by sub-adult Atlantic Sturgeon to electromagnetic and magnetic fields under controlled laboratory conditions. Fabricated EMF generators were used to emulate a range of field EMF conditions that migratory fishes could encounter in proximity to submarine HV sources. Sensor arrays and digital video recorders …