Mechanical Engineering Commons^™

Biomechanical Analysis Of Open-Skull High-Rate Traumatic Brain Injury Using Finite Element Mouse Brain Model, Lihong Lu

Electronic Thesis and Dissertation Repository

To better understand traumatic brain injury (TBI), it is necessary to correlate with injuries, which are observed from in vivo laboratory experiments, to brain mechanical responses, which can so far be best predicted by finite element (FE) models. Firstly, a previously validated FE model was improved to investigate the effect of repeated impacts and lateral movements on brain responses to ensure the accuracy and reproducibility of controlled cortical impact (CCI) across different labs. Then, a new FE mouse brain model with the detailed three-dimensional (3D), non-linear vasculature was developed to study how the vasculature affected brain response in CCI and …

Katie's Jogger, Megan Guillermo, Erin Wint, Abdullah Sulaiman, Kathryn Mangiaracina

Mechanical Engineering

Edward Robinson is an avid runner who would like to take his daughter on runs. His daughter, Katie, is 100% wheelchair bound and currently does not fit in any commercial joggers on the market. The project team was expected to design, build, and test a custom working prototype of a jogger that the sponsor can use to take his daughter on runs. This entire project was performed over a span of three quarters.

Development And Characterization Of A Biopolymer Direct-Write Process For 3d Microvascular Structures Formation., Xiaoming Fan

Electronic Theses and Dissertations

Engineering of bulk tissues has been limited by the lack of nutrient and waste exchange in these tissues without an adjacent capillary network. To produce microvasculature, a scaffold must be produced that provides temporary mechanical support and stimulate endothelial cell adhesion, growth, and morphogenesis into a vessel. However, current well-established techniques for producing microvasculature, such as electrospinning, are limited since they lack both the precision to control fiber placement in three-dimensional space and the ability to create fiber networks with predefined diameters to replicate the physiological microvascular progression from arteriole to capillary to venule. Our group has developed a “Direct-write” …

Isolated Nucleus Stiffens In Response To Low Intensity Vibration, Joshua Newberg

Boise State University Theses and Dissertations

The nucleus, central to all cellular activity, relies on both direct mechanical input and its molecular transducers to sense and respond to external mechanical stimuli. This response occurs by regulating intra-nuclear organization that ultimately determines gene expression to control cell function and fate. It has long been known that signals propagate from an extracellular environment to the cytoskeleton and into nucleus (outside-in signaling) to regulate cell behavior. Emerging evidence, however, shows that both the cytoskeleton and the nucleus have inherent abilities to sense and adapt to mechanical force, independent of each other. While it has been shown that isolated nuclei …

Predictive Simulation Of Human Movement And Applications To Assistive Device Design And Control, Vinh Nguyen

Doctoral Dissertations

Predictive simulation based on dynamic optimization using musculoskeletal models is a powerful approach for studying biomechanics of human gait. Predictive simulation can be used for a variety of applications from designing assistive devices to testing theories of motor controls. However, one of the challenges in formulating the predictive dynamic optimization problem is that the cost function, which represents the underlying goal of the walking task (e.g., minimal energy consumption) is generally unknown and is assumed a priori. While different studies used different cost functions, the qualities of the gaits with those cost functions were often not provided. Therefore, this dissertation …

Vibration Evaluation Of The Driver’S Seat Of Mf 285 Tractor In Conducting The Tillage Operations, Gholamhossein Shahgholi, Sedagat Fazeli, Saleh Harami Mousavi

Emirates Journal for Engineering Research

The purpose of this study was to investigate the effect of the tractor speed on the tractors’ seat vibration and to assess the level of comfort of the driver during the agricultural operation using moldboard and disc plows. Experiments were conducted on sandy loamy soil in a factorial experiment based on randomized complete block design with three replications. The effect of the type of tillage implement using the moldboard and disc plows, the velocity of advance in four levels of 4.5, 6 and 8.8 km/h and vibration was measured and evaluated at three directions of longitudinal (x), lateral (y) and …

Estimation Of Gait Kinematics And Kinetics From Inertial Sensor Data Using Optimal Control Of Musculoskeletal Models, Eva Dorschky, Marlies Nitschke, Ann-Kristin Seifer, Antonie J. Van Den Bogert, Bjoern M. Eskofier

Mechanical Engineering Faculty Publications

Inertial sensing enables field studies of human movement and ambulant assessment of patients. However, the challenge is to obtain a comprehensive analysis from low-quality data and sparse measurements. In this paper, we present a method to estimate gait kinematics and kinetics directly from raw inertial sensor data performing a single dynamic optimization. We formulated an optimal control problem to track accelerometer and gyroscope data with a planar musculoskeletal model. In addition, we minimized muscular effort to ensure a unique solution and to prevent the model from tracking noisy measurements too closely. For evaluation, we recorded data of ten subjects walking …

A Novel Fiber Jamming Theory And Experimental Verification, Jared Richard Chafetz

Master's Theses

This thesis developed a novel theory of fiber jamming and experimentally verified it. The theory relates the performance, which is the ratio between the stiff and soft states of a fiber jamming chamber, to three relative design parameters: the ratio of the wall thickness to the membrane inner diameter, the ratio of the fiber diameter to membrane inner diameter, and the number of fibers. These three parameters, when held constant across different chamber sizes, hold the performance constant. To test the theory, three different types of fiber jamming chambers were built in three different sizes. Each chamber was set up …

A Heterogeneous Patient-Specific Biomechanical Model Of The Lung For Tumor Motion Compensation And Effective Lung Radiation Therapy Planning, Parya Jafari

Electronic Thesis and Dissertation Repository

Radiation therapy is a main component of treatment for many lung cancer patients. However, the respiratory motion can cause inaccuracies in radiation delivery that can lead to treatment complications. In addition, the radiation-induced damage to healthy tissue limits the effectiveness of radiation treatment. Motion management methods have been developed to increase the accuracy of radiation delivery, and functional avoidance treatment planning has emerged to help reduce the chances of radiation-induced toxicity. In this work, we have developed biomechanical model-based techniques for tumor motion estimation, as well as lung functional imaging. The proposed biomechanical model accurately estimates lung and tumor motion/deformation …

In Vitro Biomechanical Analyses Of The Pcl And Medial Ligaments Of The Human Knee, Alireza Moslemian

Electronic Thesis and Dissertation Repository

Previous studies have shown that surgical treatments of PCL injuries are not successful in all cases and there is room for improvement. The effectiveness of an isolated PCL reconstruction, in the setting of what actually is a multi-ligament injury, may be inadequate, and therefore the biomechanical contribution of other ligaments in a PCL-deficient knee need to be better understood.

A new apparatus was used to analyze the effect of medial ligaments transection on the kinematics of the PCL-deficient knee during simulated clinical tests and activities of daily living. We observed that the anterior translation of the medial side of the …

System Integration Of C-Arm Robotic Prototype Using Motion Capture Guidance For Accurate Repositioning, Alireza Yazdanshenas

Mechanical Engineering Theses

One of the important surgical tools in spinal surgery is the C-Arm X-ray System. The C-Arm is a large “C” shaped and manually maneuvered arm that provides surgeons and X-ray technicians the ability to take quick quality X-rays during surgery. Because of its five degrees of freedom, the C-Arm can be manually maneuvered around the patient to provide many angles and perspectives, ensuring surgical success.

This system works fine for most surgical procedures but falls short when the C-Arm must be moved out of the way for complicated surgical procedures.

The aim of this thesis is to develop an accurate …

A Novel Method For In Vivo Evaluation Of Finger Kinematics For Analysis Of Activities Of Daily Living, Ahmed M. Tanashi

Electronic Thesis and Dissertation Repository

This thesis examines the development of a six degrees of freedom finger coordinate system that employs electromagnetic tracking to measure finger kinematics. Secondarily, this thesis validated the in vivo finger coordinate system, and is then used to examine range of motion in the fingers in patients with hand osteoarthritis. Lastly, this thesis examines the range of motion of individuals with and without hand arthritis during various activities of daily living, performed with and with joint protection program principles. This study presents a foundation for finger kinematic evaluation and describes a methodology that will be used for larger studies to be …

Investigation Of Fundamental Principles Of Rigid Body Impact Mechanics, Khalid Alluhydan

Mechanical Engineering Research Theses and Dissertations

In impact mechanics, the collision between two or more bodies is a common, yet a very challenging problem. Producing analytical solutions that can predict the post-collision motion of the colliding bodies require consistent modeling of the dynamics of the colliding bodies. This dissertation presents a new method for solving the two and multibody impact problems that can be used to predict the post-collision motion of the colliding bodies. Also, we solve the rigid body collision problem of planar kinematic chains with multiple contacts with external surfaces.

In the first part of this dissertation, we study planar collisions of Balls and …

Computational Analysis And Design Optimization Of Convective Pcr Devices, Jung Il Shu

Mechanical & Aerospace Engineering Theses & Dissertations

Polymerase Chain Reaction (PCR) is a relatively novel technique to amplify a few copies of DNA to a detectable level. PCR has already become common in biomedical research, criminal forensics, molecular archaeology, and so on. Many have attempted to develop PCR devices in numerous types for the purpose of the lab-on-chip (LOC) or point-of-care (POC). To use PCR devices for POC lab testing, the price must be lower, and the performance should be comparable to the lab devices. For current practices with the existing methods, the price is pushed up higher partially due to too much dependence on numerous developmental …

The Effect Of Radial Head Hemiarthroplasty Stem Fit On Radiocapitellar Contact Mechanics: Is Loose Fit Better Than Rigidly Fixed?, Jakub Szmit, Graham J.W. King, James A. Johnson, G. Daniel G. Langohr

Western Research Forum

Background/Methods: Radial head hemiarthroplasty is commonly employed to manage comminuted displaced fractures. With regards to implant fixation, current designs vary with some prostheses aiming to achieve a tight 'fixed' fit, and others utilizing a smooth stem with an over reamed 'loose' fit. The purpose of the present study was to evaluate the effect of radial head hemiarthroplasty stem fit on radiocapitellar contact using a finite element model which simulated both fixed (size-for-size) and loose (1, 2 & 3mm over reamed) stem fits.

Hypothesis: It was hypothesized that a loose stem fit would improve radiocapitellar contact mechanics, with increased contact area …

Investigating The Effect Of Stiffness In Hemiarthroplasty Implants, Carolyn Berkmortel, Daniel Langohr, Graham King, James Johnson

Western Research Forum

Background: Hemiarthroplasty is an attractive alternative to total arthroplasty because it conserves tissue, allows for quicker recovery, and has a lower cost. However, likely due to the high stiffness of the implant, hemiarthroplasties often lead to accelerated wear of the opposing native cartilage.

Hypothesis and Methods: The purpose of this study was to investigate the maximum contact stress on the capitellum for different currently available biomaterials in radial head hemiarthroplasty and compare them to the native radial head. A finite element model was developed in ABAQUS (Dassault Systèmes Simulia Corp., RI, USA). An axial load of 100N was applied to …

Adapted Trailer Hitching System, Joseph Neil Hearn, Maxwell M. Selna, Maximilian D. Cossalter, Eric B. Ringsrud

Mechanical Engineering

This report highlights the entire design process of an adapted trailer hitching system for Taylor Morris: a navy veteran and quadruple amputee. This begins with problem definition through customer and product research. Objectives are generated after the problem is defined and the boundary of the project is set. This outcome of the project focuses on modifications/improvements to the vehicle side of the problem and leaves the trailers untouched. Engineering specifications are developed to constrain the concept design direction, which ultimately dictates the outcome of the final design. The final design is used as a basis to manufacture a structural prototype …

Sand Foot: A Prosthesis For Walking On Sand, Samantha A. Galicinao, John Dewing, Daniel Dugan Dotson, Christopher Urasaki

Biomedical Engineering

This critical design report describes the product development of a prosthesis for use on sand. Quality of Life Plus (QL+), a national non-profit organization aimed to develop prostheses for veterans and people with disabilities, introduced this project and its accompanying challenger, Sgt. Brady, to Cal Poly’s Interdisciplinary Senior Project class in September 2018. After consulting with Sgt. Brady and QL+ and performing extensive research, the Sand Foot team defined customer requirements and engineering specifications to meet these requirements. Comfortability, durability, and sandproof were key customer requirements. Several conceptual models were brainstormed and a final design was selected based on the …

Cooking Hand Multi-Tool, Amanda D. Meares, Amy H. Wilson, Ethan G. Littlejohn, Duania A. Evans

Biomedical Engineering

The purpose of this project was to devise a solution for Jorge Segura, a US Marine who was wounded in Afghanistan and had to have his non-dominant arm amputated above the elbow. His current prosthetic attachments are not suited to cooking tasks, so he needed a way to cook more effectively with either prosthetic attachments or accessibility devices. The main tasks that he needed help with was holding down food on cutting boards and stabilizing pots, pans, and bowls especially when stirring. After background research, exploring commercially available devices, and talking with our challenger, our solution was to design three …

Investigating Grip Range Of Motion And Force Exerted By Individuals With And Without Hand Arthritis During Functional Tasks And While Swinging A Golf Club, Sara Frances Holland

Electronic Thesis and Dissertation Repository

Hand arthritis is the leading cause of disability in individuals over the age of 50; resulting in dysfunction and pain, making activities of daily living and recreational activities such as golf difficult. Few studies have been conducted on the biomechanical response of individuals with hand arthritis when performing functional activities. This research quantified hand grip movements and strength differences seen in individuals with hand arthritis. Using a video-based motion capture system (Dartfish), a grip limitation of 17.2% (maximum flexion), and 12.7% (maximum extension) was discovered. A wireless finger force measurement system (FingerTPS), was used to show that larger diameter, softer …

Development Of A Sonically Powered Biodegradable Nanogenerator For Bone Regeneration, Avi S. Patel

University Scholar Projects

Background: Reconstruction of bone fractures and defects remains a big challenge in orthopedic surgery. While regenerative engineering has advanced the field greatly using a combination of biomaterial scaffolds and stem cells, one matter of difficulty is inducing osteogenesis in these cells. Recent works have shown electricity’s ability to promote osteogenesis in stem cell lines when seeded in bone scaffolds; however, typical electrical stimulators are either (a) externally housed and require overcomplex percutaneous wires be connected to the implanted scaffold or (b) implanted non-degradable devices which contain toxic batteries and require invasive removal surgeries.

Objective: Here, we establish a biodegradable, piezoelectric …

Development Of A Sonically Powered Biodegradable Nanogenerator For Bone Regeneration, Avi Patel

Honors Scholar Theses

Background: Reconstruction of bone fractures and defects remains a big challenge in orthopedic surgery. While regenerative engineering has advanced the field greatly using a combination of biomaterial scaffolds and stem cells, one matter of difficulty is inducing osteogenesis in these cells. Recent works have shown electricity’s ability to promote osteogenesis in stem cell lines when seeded in bone scaffolds; however, typical electrical stimulators are either (a) externally housed and require overcomplex percutaneous wires be connected to the implanted scaffold or (b) implanted non-degradable devices which contain toxic batteries and require invasive removal surgeries.

Objective: Here, we establish a biodegradable, piezoelectric …

Danny’S Recumbent Bike Accessibility Device Final Design Report, Joseph J. Lee, Huy Nguyen, Jack Mcatee, John Kulick

Mechanical Engineering

The purpose of this document is to fully define our design solution and explain our manufacturing and testing results. Our project’s goal is to find a way to allow Danny Knutson, a retired Navy pilot and incomplete quadriplegic with limited use of his arms and an impaired sense of balance, to enter and exit his recumbent tricycle without any discomfort for him or his aide. We completed multiple interviews with Danny, patent research, existing product research, and other technical literature research in order to fully understand the problem. We synthesized this information to create a concrete list of customer wants …

Factors Affecting Patellar Mechanics And Bone Strain In Patients With Crouch Gait, Erika Ramirez

Boise State University Theses and Dissertations

Crouch gait is a musculoskeletal impairment that results in higher than normal stresses at the patellofemoral (PF) joint that can lead to instances of anterior knee pain and loss of ambulation. The impact of commonly implemented surgical procedures to correct for crouch gait can be quantified by evaluating stresses and underlying patellar bone strain during a gait cycle. The aims of this thesis work were (1) to analyze changes in PF mechanics and patellar bone strain between pre- and postoperative conditions; (2) to quantify the variability of predicted patellar strain due to different kinematic/loading profiles or patellar material properties; and …

The Effects Of Bone Morphogenic Protein 2 On The Viability And Proliferation Of Dental Pulp Stem Cell Isolates, Joseph Cinelli

UNLV Theses, Dissertations, Professional Papers, and Capstones

Growth factor is an umbrella term used to describe a signaling molecule present in organisms that serves the purpose of influencing a stimulatory or inhibitory response from the target cell it acts on. Growth factors are categorized and classified by the types of tissues they act on and the cellular responses they illicit. For example, there are growth factors that act primarily in connective tissue on fibroblasts and they are aptly classified as the fibroblast growth factor family. Similarly, there is another family of growth factors that act on bone forming cells, among others, and they are known as bone …

The Affective Perceptual Model: Enhancing Communication Quality For Persons With Pimd, Jadin Tredup

UNLV Theses, Dissertations, Professional Papers, and Capstones

Methods for prolonged compassionate care for persons with Profound Intellectual and Multiple Disabilities (PIMD) require a rotating cast of import people in the subjects life in order to facilitate interaction with the external environment. As subjects continue to age, dependency on these people increases with complexity of communications while the quality of communication decreases. It is theorized that a machine learning (ML) system could replicate the attuning process and replace these people to promote independence. This thesis extends this idea to develop a conceptual and formal model and system prototype.

The main contributions of this thesis are: (1) proposal of …

Final Design Report For The Bioburden Pre-Cleaning Device And Dr. Mark Rasnake At The University Of Tennessee Medical Center, Katherine Elizabeth Stiles, Megan Pitz, Kayla Franklin, Simran Dayal, Austin Bullock

Chancellor’s Honors Program Projects

No abstract provided.

How Infant Positioning Impacts Hip Motion And The Associated Implications For Babies With Hip Dysplasia, Lauren Buchele

Biomedical Engineering Undergraduate Honors Theses

Developmental dysplasia of the hip (DDH) refers to a group of disorders, ranging from slight instability (Grades 1-3) to a severe dislocation (Grade 4) of the femoral head from the acetabulum [1]. In order to treat DDH in infants, a reduction procedure and the use of a lower body harness to secure the hip joint as the bones and ligaments re-form properly is typically prescribed. The Pavlik Harness is currently the “gold-standard” orthopedic device used to place hips in proper positioning. However, little research has been reported on the biomechanical affects during use of these device types.

Although the Pavlik …

Mechanical And Tribological Behaviour Of Treated And Untreated Moringa Oleifera Pods Fiber Reinforced Epoxy Polymer Composite For Packaging Applications, Prakash Sampath, Senthil Kumar V.S Dr

Journal of Applied Packaging Research

Researchers now focus on the use of natural fiber polymer composites materials for packing applications. This attention is due to their low cost and renewable characteristics. Fabrication of composites with the use of renewable resources has many benefits of alternating from an appropriate management and reduction in industrial wastages, ecofriendly behaviour to cost effectiveness. The artificial fibers in packing industries can be replaced by natural fibers in the areas where stiffness and high strength are not the primary requirement. In the last decade the use of Natural fibers in the place of artificial fibers for reinforcements in epoxy resin matrix …

Graduate Keynote. Golf Grip Force Evaluation In Individuals With And Without Hand Arthritis Using A New Wearable Sensor Technology, Sara Frances Holland, Emily Lalone, Louis M. Ferreira, James P. Dickey

Western Research Forum

BACKGROUND

Hand osteoarthritis (H-OA) is the most common type of osteoarthritis largely affecting individuals over 45. H-OA involves pain, loss of grip strength and limiting participation in recreational activities such as golf. Currently, a number of ‘arthritic’ grips are designed using joint protection principles to ‘reduce hand forces and tight gripping’. However, no comprehensive examinations in their effectiveness have been conducted.

HYPOTHESIS

The purpose of this study is to systematically analyse the hand forces produced from various golf grips and arthritis grips at the distal-phalanges of the hand-grip interface in individuals with and without hand arthritis using new wearable sensor …