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Biological Engineering

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Coronary artery science

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Full-Text Articles in Mechanical Engineering

Computational Analysis Of Hybrid Norwood Circulation With Distal Aortic Arch Obstruction And Reverse Blalock-Taussig Shunt, Andres Ceballos, I. Ricardo Argueta-Morales, Eduardo Divo, Ruben Osorio, Christopher A. Caldarone, Alain J. Kassab, William M. Decampli May 2014

Computational Analysis Of Hybrid Norwood Circulation With Distal Aortic Arch Obstruction And Reverse Blalock-Taussig Shunt, Andres Ceballos, I. Ricardo Argueta-Morales, Eduardo Divo, Ruben Osorio, Christopher A. Caldarone, Alain J. Kassab, William M. Decampli

Eduardo Divo

BACKGROUND: The hemodynamics characteristics of the hybrid Norwood (HN) procedure differ from those of the conventional Norwood and are not fully understood. We present a multi-scale model of HN circulation to understand local hemodynamics and effects of aortic arch stenosis and a reverse Blalock-Taussig shunt (RBTS) on coronary and carotid perfusion. METHODS: Four 3-dimensional models of four HN anatomic variants were developed, with and without 90% distal preductal arch stenosis and with and without a 4-mm RBTS. A lumped parameter model of the circulation was coupled to a local 3-dimensional computational fluid dynamics model. Outputs from the lumped parameter model …