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Exploring Poly(Ethylene Glycol) As A Suitable Material For Peripheral Nerve Regeneration Scaffolds Manufactured By Stereolithography, Nubia Zuverza
Exploring Poly(Ethylene Glycol) As A Suitable Material For Peripheral Nerve Regeneration Scaffolds Manufactured By Stereolithography, Nubia Zuverza
Open Access Theses & Dissertations
One of the challenges in tissue engineering is to have spatial and temporal control over the biological elements within a scaffold used to guide regeneration for example of transected nerves. Some of the physical and chemical characteristics to regulate include incorporation of bioactive domains and release of chemical signals. This study presents the use of stereolithography (SL) to incorporate localized domains for cell adhesion in addition to include releasable nerve growth factor (NGF) in the process of building poly(ethylene glycol)diacrylate (PEGda) hydrogel scaffolds. Besides providing sites for cell attachment, an ideal nerve guidance conduit (NGC) should be able to release …