Bioimaging and Biomedical Optics Commons^™

Quantification Of Mitral Regurgitation With Mr Phase-Velocity Mapping Using A Control Volume Method, George P. Chatzimavroudis, John N. Oshinski, Roderic I. Pettigrew, Peter G. Walker, Robert H. Franch, Ajit P. Yoganathan

Chemical & Biomedical Engineering Faculty Publications

Reliable diagnosis and quantification of mitral regurgitation are important for patient management and for optimizing the time for surgery. Previous methods have often provided suboptimal results. The aim of this in vitro study was to evaluate MR phase-velocity mapping in quantifying the mitral regurgitant volume (MRV) using a control volume (CV) method. A number of contiguous slices were acquired with all three velocity components measured. A CV was then selected, encompassing the regurgitant orifice. Mass conservation dictates that the net inflow into the CV should be equal to the regurgitant flow. Results showed that a CV, the boundary voxels of …