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Electrospinning

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Novel Nanofiber Structures And Advanced Tissue Engineering Applications, Vince Beachley May 2011

Novel Nanofiber Structures And Advanced Tissue Engineering Applications, Vince Beachley

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Extracellular matrix (ECM) nanofibers such as collagen and elastin make up an important component of natural tissues. These structural components serve to impart mechanical strength and provide locations for cell attachment and biomolecule storage. Cells respond to their structural environment in a wide variety of ways beyond physical support, and it has been demonstrated that this environment directly modulates cell behaviors such as, morphology, differentiation, ECM production, attachment, and migration. ECM nanofibers also play an important role as a template for tissue formation during development, remodeling, and regeneration. Nanofiber based tissue engineering strategies aim to mimic the geometry of the …


Study Of Electrospinning Of Property-Modulated Biomedical Microfibers, Scott Taylor May 2008

Study Of Electrospinning Of Property-Modulated Biomedical Microfibers, Scott Taylor

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Electrospinning technologies have been of great interest in recent years, due in large part to developments in the field of Bioengineering, including the preparation of novel polymers and advances in tissue engineering, specifically for therapeutic applications. The electrospinning process is, in general, a very benign process that allows the preparation, under mild conditions, of micro- and nano-scale fibers from fiberforming materials, as well as traditionally non-fiber forming materials. This process is of specific interest to the biomedical community because it affords an opportunity to create highly-tailored novel constructs with a multitude of possible uses. Some proposed uses for these materials …