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Biomedical Engineering and Bioengineering Commons

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2013

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Interstitial cell seeding

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Interstitial Cell Seeding And Dynamic Conditioning Of Aortic Heart Valve Scaffolds, Allison Kennamer Dec 2013

Interstitial Cell Seeding And Dynamic Conditioning Of Aortic Heart Valve Scaffolds, Allison Kennamer

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In 2011, U.S. Markets for Heart Valve Repair and Replacement Products estimated that roughly four million people in the United States are diagnosed with a heart valve disorder annually. And in the following year, the American Heart Association reported that approximately 35,000 deaths in the US were either directly or indirectly attributed to heart valve disease. Diseases of the heart valve are degenerative in nature and therefore progressively worsen unbeknownst to the patient until symptoms become clinically relevant. By this time, the valve is in such poor condition that complete replacement is often the only effective treatment. Current solutions are …