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Biomedical Engineering and Bioengineering Commons

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Full-Text Articles in Biomedical Engineering and Bioengineering

Biomedical Photoacoustic Imaging Using Gas-Coupled Laser Acoustic Detection, Jami L. Johnson May 2013

Biomedical Photoacoustic Imaging Using Gas-Coupled Laser Acoustic Detection, Jami L. Johnson

Student Research Initiative

Several detection methods have been explored for photoacoustic and ultrasound imaging of biological tissues. Piezoelectric transducers are commonly used, which require contact with the sample and have limiting bandwidth characteristics. Interferometry detection exhibits improved bandwidth characteristics and resolution, yet generally require complicated optics and the incorporation of a contacting reflective medium. Here, we report the use of a noncontact photoacoustic and laser-ultrasound imaging system that does not require the use of a reflective layer. A simple, robust technique known as gas-coupled laser acoustic detection is used, which has previously been applied to composite material evaluation. This technique has the potential ...


Biomedical Photoacoustic Imaging Using Gas-Coupled Laser Acoustic Detection, Jami Johnson May 2013

Biomedical Photoacoustic Imaging Using Gas-Coupled Laser Acoustic Detection, Jami Johnson

Student Research Initiative

Several detection methods have been explored for photoacoustic and ultrasound imaging of biological tissues. Piezoelectric transducers are commonly used, which require contact with the sample to be imaged and have limiting bandwidth characteristics. Interferometry detection exhibits improved bandwidth characteristics and resolution, yet generally require complicated optics and the incorporation of a contacting reflective medium. In this paper, we report the use of a noncontact photoacoustic imaging system that does not require the use of a reflective layer. A simple, robust technique known as gas-coupled laser acoustic detection is used, which has previously been applied to evaluation of composite materials. This ...


Toward Characterization Of Diseased Vascular Structures Using Noncontact Photoacoustic And Laser-Ultrasound Imaging: A Phantom Study, Jami Lynne Johnson May 2013

Toward Characterization Of Diseased Vascular Structures Using Noncontact Photoacoustic And Laser-Ultrasound Imaging: A Phantom Study, Jami Lynne Johnson

Boise State University Theses and Dissertations

Visualizing and characterizing atherosclerotic plaques is important in determining the vulnerability of a plaque to rupture. To evaluate rupture risk, several compositional factors should be evaluated, including inflammation, the presence and size of lipid pools, thickness of the fibrous cap, and calcification. Currently, a need exists for an imaging modality that can detect each of these factors in a safe, noninvasive manner with high resolution and contrast at clinically relevant depths. Photoacoustic imaging is a growing field that has the potential to improve plaque diagnosis. Spectroscopic methods have shown promise toward detection of constituents of plaque with unique optical absorption ...