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Biomedical Engineering and Bioengineering Commons™
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Articles 1 - 30 of 49
Full-Text Articles in Biomedical Engineering and Bioengineering
Comparison Of 4d Phase-Contrast Mri Flow Measurements To Computational Fluid Dynamics Simulations Of Cerebrospinal Fluid Motion In The Cervical Spine, Theresia Yiallourou, Jan Robert Kroger, Nikolaos Stergiopulos, David Maintz, Bryn A. Martin, Alexander C. Bunck
Comparison Of 4d Phase-Contrast Mri Flow Measurements To Computational Fluid Dynamics Simulations Of Cerebrospinal Fluid Motion In The Cervical Spine, Theresia Yiallourou, Jan Robert Kroger, Nikolaos Stergiopulos, David Maintz, Bryn A. Martin, Alexander C. Bunck
Mechanical Engineering Faculty Research
Cerebrospinal fluid (CSF) dynamics in the cervical spinal subarachnoid space (SSS) have been thought to be important to help diagnose and assess craniospinal disorders such as Chiari I malformation (CM). In this study we obtained time-resolved three directional velocity encoded phase-contrast MRI (4D PC MRI) in three healthy volunteers and four CM patients and compared the 4D PC MRI measurements to subject-specific 3D computational fluid dynamics (CFD) simulations. The CFD simulations considered the geometry to be rigid-walled and did not include small anatomical structures such as nerve roots, denticulate ligaments and arachnoid trabeculae. Results were compared at nine axial planes …
Optimal Inertial Sensor Placement And Motion Detection For Epileptic Seizure Patient Monitoring, Babak Kamalizonouzi
Optimal Inertial Sensor Placement And Motion Detection For Epileptic Seizure Patient Monitoring, Babak Kamalizonouzi
Electronic Thesis and Dissertation Repository
Use of inertial sensory systems to monitor and detect seizure episodes in patients suffering from epilepsy is investigated via numerical simulations and experiments. Numerical simulations employ a mathematical model that is able to predict human body dynamic responses during a typical epileptic seizure. An optimized inertial sensor placement procedure is developed to address achievement of highest possible sensing resolution in determining angular accelerations with minimal errors. In addition, a joint torque estimation procedure is formulated to assist in the future development of a possible detection scheme. Experimental motion data obtained from an epileptic seizure patient as well as a healthy …
Handitrike - Recumbent Tricycle, Sean Higginson, Kevin Howie, Vinay Patel
Handitrike - Recumbent Tricycle, Sean Higginson, Kevin Howie, Vinay Patel
Mechanical Engineering
This report covers the design and construction of the recumbent racing tricycle for Mr. Robert T. Kelly, a disabled veteran. Unfortunately Rob’s right leg is five inches shorter than his left one and therefore is unable to properly operate standard cranks. Our team HandiTrike is composed of Sean Higginson, Kevin Howie, and Vinay Patel and our project requires us to come up with a design that is feasible to complete within the given three quarters, as well as allow Rob to gain full use of his tricycle. Currently Rob ‘s trike uses the standard crank set up found on most …
My Lecture Notes (Power Plant Engineering) - Chapter 4, Dr Alireza Zolfaghari
My Lecture Notes (Power Plant Engineering) - Chapter 4, Dr Alireza Zolfaghari
Dr Alireza Zolfaghari
No abstract provided.
Implementation Of Magnetic Resonance Elastography For The Investigation Of Traumatic Brain Injuries, Thomas Boulet
Implementation Of Magnetic Resonance Elastography For The Investigation Of Traumatic Brain Injuries, Thomas Boulet
Department of Engineering Mechanics: Dissertations, Theses, and Student Research
Magnetic resonance elastography (MRE) is a potentially transformative imaging modality allowing local and non-invasive measurement of biological tissue mechanical properties. It uses a specific phase contrast MR pulse sequence to measure induced vibratory motion in soft material, from which material properties can be estimated. Compared to other imaging techniques, MRE is able to detect tissue pathology at early stages by quantifying the changes in tissue stiffness associated with diseases. In an effort to develop the technique and improve its capabilities, two inversion algorithms were written to evaluate viscoelastic properties from the measured displacements fields. The first one was based on …
My Lecture Notes (Power Plant Engineering) - Chapter 3, Dr Alireza Zolfaghari
My Lecture Notes (Power Plant Engineering) - Chapter 3, Dr Alireza Zolfaghari
Dr Alireza Zolfaghari
No abstract provided.
The Design And Testing Of A Solar Autoclave With Broad Spectrum Sterilization Capabilities, Sarah S. Trabia
The Design And Testing Of A Solar Autoclave With Broad Spectrum Sterilization Capabilities, Sarah S. Trabia
Honors College Theses
Energy is difficult to come by in developing countries and this interferes with the ability of doctors to provide good healthcare to their patients. Without decent sterilization, patients can become infected and diseases can spread throughout hospitals. This study involves designing a solar autoclave for developing countries that is as efficient as electrical autoclaves. The design is intended to not require any electrical input and to be affordable to those who cannot afford advanced medical equipment. Once the solar autoclave is designed, it will be tested to determine if it can sterilize equipment against a variety of different bacteria, including …
Development Of A Novel Handheld Device For Active Compensation Of Physiological Tremor, Abhijit Saxena
Development Of A Novel Handheld Device For Active Compensation Of Physiological Tremor, Abhijit Saxena
Electronic Thesis and Dissertation Repository
In microsurgery, the human hand imposes certain limitations in accurately positioning the tip of a device such as scalpel. Any errors in the motion of the hand make microsurgical procedures difficult and involuntary motions such as hand tremors can make some procedures significantly difficult to perform. This is particularly true in the case of vitreoretinal microsurgery. The most familiar source of involuntary motion is physiological tremor. Real-time compensation of tremor is, therefore, necessary to assist surgeons to precisely position and manipulate the tool-tip to accurately perform a microsurgery. In this thesis, a novel handheld device (AID) is described for compensation …
My Lecture Notes (Power Plant Engineering) - Chapter 2, Dr Alireza Zolfaghari
My Lecture Notes (Power Plant Engineering) - Chapter 2, Dr Alireza Zolfaghari
Dr Alireza Zolfaghari
No abstract provided.
کارگاه تخصصی آسايش حرارتی, Dr Alireza Zolfaghari
کارگاه تخصصی آسايش حرارتی, Dr Alireza Zolfaghari
Dr Alireza Zolfaghari
No abstract provided.
Comparison Of Phenolic Compounds And Antioxidant Capacities Of Traditional Sorghum Beers With Other Alcoholic Beverages, Fatouma Abdoul-Latif, Romaric G. Bayili, Louis C. Obame, Mamoudou H. Dicko Prof.
Comparison Of Phenolic Compounds And Antioxidant Capacities Of Traditional Sorghum Beers With Other Alcoholic Beverages, Fatouma Abdoul-Latif, Romaric G. Bayili, Louis C. Obame, Mamoudou H. Dicko Prof.
Pr. Mamoudou H. DICKO, PhD
Thirty samples of sorghum beers “dolo” were selected from traditionally fermented household manufacturers from Burkina Faso. Dolo samples were screened for their total phenolic content, proanthocyanidins and putative antioxidant capacities, and were compared with industrial beers and wines. Total phenols were measured using the Folin-Ciocalteu method. Proanthocyanidins content were determined by the method of HCl-butanol hydrolysis. Antioxidant activities were evaluated both with 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay and by the trolox equivalent antioxidant capacity (TEAC) using 2,2’-azinobis(3-ethyl-benzothiazoline-6-sulfonic acid radical) (ABTS•+). The average contents of total phenols and proanthocyanidins were 506 μg GAE/ml of dolo and 45 μg APE/ml of dolo, respectively. An …
Designing For Success: Developing Engineers Who Consider Universal Design Principles, Kimberly Edginton Bigelow
Designing For Success: Developing Engineers Who Consider Universal Design Principles, Kimberly Edginton Bigelow
Mechanical and Aerospace Engineering Faculty Publications
Engineers must design for a diverse group of potential users of their products; however, engineering curricula rarely include an emphasis on universal design principles. This research article details the effectiveness of a design project implemented in a first-year engineering course in an effort to raise awareness of the need for engineers to be more inclusive when designing. Students were asked to apply universal design principles to redesign an engineering laboratory to make it more usable to all, including individuals with disabilities who use the room. A representative from the university’s disability services staff, as well as individuals with first-hand experience …
Enhancing The Engineering Curriculum: Defining Discovery Learning At Marquette University, Jay R. Goldberg, Mark L. Nagurka
Enhancing The Engineering Curriculum: Defining Discovery Learning At Marquette University, Jay R. Goldberg, Mark L. Nagurka
Biomedical Engineering Faculty Research and Publications
This paper summarizes the results of our investigation into the feasibility of increasing the level of discovery learning in the College of Engineering (COE) at Marquette University. We review the education literature, document examples of discovery learning currently practiced in the COE and other schools, and propose a Marquette COE-specific definition of discovery learn-ing. Based on our assessment of the benefits, costs, and tradeoffs associated with increasing the level of discovery learning, we pre-sent several recommendations and identify resources required for implementation. These recommendations may be helpful in enhancing engineering education at other schools.
تمرين سري اول, Dr Alireza Zolfaghari
My Lecture Notes (Heat Transfer - Chapter 1), Dr Alireza Zolfaghari
My Lecture Notes (Heat Transfer - Chapter 1), Dr Alireza Zolfaghari
Dr Alireza Zolfaghari
No abstract provided.
Preoperative Planning Of Robotics-Assisted Minimally Invasive Cardiac Surgery Under Uncertainty, Hamidreza Azimian
Preoperative Planning Of Robotics-Assisted Minimally Invasive Cardiac Surgery Under Uncertainty, Hamidreza Azimian
Electronic Thesis and Dissertation Repository
In this thesis, a computational framework for patient-specific preoperative planning of Robotics-Assisted Minimally Invasive Cardiac Surgery (RAMICS) is developed. It is expected that preoperative planning of RAMICS will improve the rate of success by considering robot kinematics, patient-specific thoracic anatomy, and procedure-specific intraoperative conditions. Given the significant anatomical features localized in the preoperative computed tomography images of a patient's thorax, port locations and robot orientations (with respect to the patient's body coordinate frame) are determined to optimize characteristics such as dexterity, reachability, tool approach angles and maneuverability. In this thesis, two approaches for preoperative planning of RAMICS are proposed that …
Toxicity Assessment And Analgesic Activity Investigation Of Aqueous Acetone Extracts Of Sida Acuta Burn F. And Sida Cordifolia L. (Malvaceae), Medicinal Plants Of Burkina Faso, Kiessoum Konate, Adama Hilou, Raïssa Rr Aworet-Samseny, Alain Souza, Nicolas Barro, Mamoudou H. Dicko Prof., Jacques Datté, Bertrand M’Batchi
Toxicity Assessment And Analgesic Activity Investigation Of Aqueous Acetone Extracts Of Sida Acuta Burn F. And Sida Cordifolia L. (Malvaceae), Medicinal Plants Of Burkina Faso, Kiessoum Konate, Adama Hilou, Raïssa Rr Aworet-Samseny, Alain Souza, Nicolas Barro, Mamoudou H. Dicko Prof., Jacques Datté, Bertrand M’Batchi
Pr. Mamoudou H. DICKO, PhD
Background Sida acuta Burn f. and Sida cordifolia L. (Malvaceae) are traditionally used in Burkina Faso to treat several ailments, mainly pains, including abdominal infections and associated diseases. Despite the extensive use of these plants in traditional health care, literature provides little information regarding their toxicity and the pharmacology. This work was therefore designed to investigate the toxicological effects of aqueous acetone extracts of Sida acuta Burn f. and Sida cordifolia L. Furthermore, their analgesic capacity was assessed, in order to assess the efficiency of the traditional use of these two medicinal plants from Burkina Faso. Method For acute toxicity …
Vision-Based Robot Control In The Context Of Human-Machine Interactions, Andrzej Nycz
Vision-Based Robot Control In The Context Of Human-Machine Interactions, Andrzej Nycz
Doctoral Dissertations
This research has explored motion control based on visual servoing – in the context of complex human-machine interactions and operations in realistic environments. Two classes of intelligent robotic systems were studied in this context: operator assistance with a high dexterity telerobotic manipulator performing remote tooling-centric tasks, and a bio-robot for X-ray imaging of lower extremity human skeletal joints during natural walking. The combination of human-machine interactions and practical application scenarios has led to the following fundamental contributions: 1) exploration and evaluation of a new concept of acquiring fluoroscope images of musculoskeletal features of interest during natural human motion, 2) creation …
Changes In In Vivo Knee Contact Forces Through Gait Modification, Allison Kinney, Thor F. Besier, Amy Slider, Scott L. Delp, Darryl D. D'Lima, Benjamin J. Fregly
Changes In In Vivo Knee Contact Forces Through Gait Modification, Allison Kinney, Thor F. Besier, Amy Slider, Scott L. Delp, Darryl D. D'Lima, Benjamin J. Fregly
Mechanical and Aerospace Engineering Faculty Publications
Gait modification represents a non-invasive method for reducing knee joint loading in patients with knee osteoarthritis. Previous studies have shown that a variety of gait modifications are effective in reducing the external knee adduction moment. The external knee adduction moment is often used as a surrogate measure of medial compartment force. However, a recent study showed that reductions in the external knee adduction moment do not guarantee reductions in medial compartment loads. Therefore, direct measurement of changes in knee contact force is important for determining the effectiveness of gait modifications. A previous study found that medial thrust gait and walking …
Design, Analysis And Testing Of Haptic Feedback System For Laparoscopic Graspers In In Vivo Surgical Robots, Nikhil Salvi
Design, Analysis And Testing Of Haptic Feedback System For Laparoscopic Graspers In In Vivo Surgical Robots, Nikhil Salvi
Department of Mechanical and Materials Engineering: Dissertations, Theses, and Student Research
Laparo-Endoscopic Single Site (LESS) Robotics Surgery is an advanced technology in the field of Minimally Invasive Surgery (MIS). The LESS surgical robots significantly improve the surgeon’s accuracy, dexterity and visualization, and reduce the invasiveness of surgical procedure results in faster recovery time and improved cosmetic results. In a standard robotic endosurgery, the palpation of tissues is performed by laparoscopic graspers located at the end effectors. The master-slave configuration in robotic surgery leads in remote access to the operation site. Therefore, surgeon’s ability to perceive valuable sensory information is severely diminished. Sensory information such as haptics, which is essential for safe …
Toward A Gpu-Accelerated Immersed Boundary Method For Wind Forecasting Over Complex Terrain, Rey Deleon, Kyle Felzien, Inanc Senocak
Toward A Gpu-Accelerated Immersed Boundary Method For Wind Forecasting Over Complex Terrain, Rey Deleon, Kyle Felzien, Inanc Senocak
Mechanical and Biomedical Engineering Faculty Publications and Presentations
A short-term wind power forecasting capability can be a valuable tool in the renewable energy industry to address load-balancing issues that arise from intermittent wind fields. Although numerical weather prediction models have been used to forecast winds, their applicability to micro-scale atmospheric boundary layer flows and ability to predict wind speeds at turbine hub height with a desired accuracy is not clear. To address this issue, we develop a multi-GPU parallel flow solver to forecast winds over complex terrain at the micro-scale, where computational domain size can range from meters to several kilometers. In the solver, we adopt the immersed …
Evaluation Of Autonomous Robotic Milling Methodology For Natural Tooth-Shaped Implants Based On Sko Optimization, Yongki Yoon
Evaluation Of Autonomous Robotic Milling Methodology For Natural Tooth-Shaped Implants Based On Sko Optimization, Yongki Yoon
Mechanical & Aerospace Engineering Theses & Dissertations
Robotic surgery is one of the most demanding and challenging applications in the field of automatic control. One of the conventional surgeries, the dental implantation, is the standard methodology to place the artificial tooth root composed of titanium material into the upper or lower jawbone. During the dental implant surgery, mechanical removal of the bone material is the most critical procedure because it may affect the patient's safety including damage to the mandibular canal nerve and/or piercing the maxillary sinus. With this problem, even though short term survival rates are greater than 95%, long term success rate of the surgery …
Weightlifting Performance Is Related To Kinematic And Kinetic Patterns Of The Hip And Knee Joints, Kristof Kipp, Josh Redden, Michelle B. Sabick, Chad Harris
Weightlifting Performance Is Related To Kinematic And Kinetic Patterns Of The Hip And Knee Joints, Kristof Kipp, Josh Redden, Michelle B. Sabick, Chad Harris
Mechanical and Biomedical Engineering Faculty Publications and Presentations
The purpose of this study was to investigate correlations between biomechanical outcome measures and weightlifting performance. Joint kinematics and kinetics of the hip, knee, and ankle were calculated while ten subjects performed a clean at 85% of 1-RM. Kinematic and kinetic time-series patterns were extracted with principal components analysis. Discrete scores for each time-series pattern were calculated and used to determine how each pattern was related to body-mass normalized 1-RM. Two hip kinematic and two knee kinetic patterns were significantly correlated with relative 1-RM. The kinematic patterns captured hip and trunk motions during the first pull and hip joint motion …
Kinematic And Kinetic Synergies Of The Lower Extremities During The Pull In Olympic Weightlifting, Kristof Kipp, Josh Redden, Michelle Sabick, Chad Harris
Kinematic And Kinetic Synergies Of The Lower Extremities During The Pull In Olympic Weightlifting, Kristof Kipp, Josh Redden, Michelle Sabick, Chad Harris
Mechanical and Biomedical Engineering Faculty Publications and Presentations
The purpose of this study was to identify multijoint lower extremity kinematic and kinetic synergies in weightlifting and compare these synergies between joints and across different external loads. Subjects completed sets of the clean exercise at loads equal to 65, 75, and 85% of their estimated 1-RM. Functional data analysis was used to extract principal component functions (PCF's) for hip, knee, and ankle joint angles and moments of force during the pull phase of the clean at all loads. The PCF scores were then compared between joints and across loads to determine how much of each PCF was present at …
Propagation Of Ultrasound Through Freshly Excised Human Calvarium, Armando Garcia Noguera
Propagation Of Ultrasound Through Freshly Excised Human Calvarium, Armando Garcia Noguera
Department of Engineering Mechanics: Dissertations, Theses, and Student Research
The propagation of ultrasound through complex biological media, such as the human calvarium, poses a great challenge for modern medicine. Several ultrasonic techniques commonly used for treatment and diagnosis in most of the human body are still difficult to apply to the human brain, in part, because of the properties of the skull. Moreover, an understanding of the biomechanics of transcranial ultrasound may provide needed insight into the problem of blast wave induced traumatic brain injury (TBI). In the present study, the spatial variability of ultrasonic properties was evaluated for relevant frequencies of 0.5, 1, and 2.25 MHz. A total …
Antibacterial Activity Against Beta- Lactamase Producing Methicillin And Ampicillin-Resistants Staphylococcus Aureus: Fractional Inhibitory Concentration Index (Fici) Determination, Kiessoun K Onate, Jacques François Mavoungou, Alexis Nicaise Lepengué, Raïssa Rr Aworet-Samseny, Adama Hilou, Mamoudou H. Dicko Prof., Bertrand M’Batchi
Antibacterial Activity Against Beta- Lactamase Producing Methicillin And Ampicillin-Resistants Staphylococcus Aureus: Fractional Inhibitory Concentration Index (Fici) Determination, Kiessoun K Onate, Jacques François Mavoungou, Alexis Nicaise Lepengué, Raïssa Rr Aworet-Samseny, Adama Hilou, Mamoudou H. Dicko Prof., Bertrand M’Batchi
Pr. Mamoudou H. DICKO, PhD
The present study reports the antibacterial capacity of alkaloid compounds in combination with Methicillin and Ampicillin-resistants bacteria isolated from clinical samples. The resistance of different bacteria strains to the current antibacterial agents, their toxicity and the cost of the treatment have led to the development of natural products against the bacteria resistant infections when applied in combination with conventional antimicrobial drugs. The antibacterial assays in this study were performed by using inhibition zone diameters, MIC, MBC methods, the time-kill assay and the Fractional Inhibitory Concentration Index (FICI) determination. On the whole, fifteen Gram-positive bacterial strains (MRSA/ARSA) were used. Negative control …
Investigation Of In-Vivo Hindfoot And Orthotic Interactions Using Bi-Planar X-Ray Fluoroscopy, Kristen M. Bushey
Investigation Of In-Vivo Hindfoot And Orthotic Interactions Using Bi-Planar X-Ray Fluoroscopy, Kristen M. Bushey
Electronic Thesis and Dissertation Repository
A markerless RSA method was used to determine the effect of orthotics on the normal, pes planus and pes cavus populations. Computed tomography (CT) was used to create bone models that were imported into the virtual environment. Joint coordinate systems were developed to measure kinematic changes in the hindfoot during weight-bearing gait and quiet standing. The objectives of this thesis were to (1) implement a fluoroscopy-based markerless RSA system on the foot, (2) determine the effect of various orthotics at midstance of fully weight-bearing dynamic gait, and (3) determine the effect of orthotics as measured using three different techniques. Every …
Polygrasp: Reach; Myoelectric Prosthetic Hand Iteration, Devon Patrick Augustus, Mighells Blaed Deuel, Ian Noel Fraser, Nicholas Philip Moesser
Polygrasp: Reach; Myoelectric Prosthetic Hand Iteration, Devon Patrick Augustus, Mighells Blaed Deuel, Ian Noel Fraser, Nicholas Philip Moesser
Mechanical Engineering
Amputations are a common occurrence in soldiers returning home who have suffered the effects of IED and munitions explosions. For upper limb amputees, trans-radial amputations are the most common. Traditional hook devices do not offer an adequate level of normalcy for users, prompting the use of myoelectric devices. While current myoelectric devices do offer a more natural experience, they come with a host of other problems that makes their adoption by service personnel not desirable or not permitted by the VA. PolyGrasp Reach seeks to reduce weight and cost and improve performance. This addresses several of the issues with devices …
Hydraulically Driven Mechanical Representation Of A Biological System, Andrea Argouarch, Michael Mceachern, Brandon Parham
Hydraulically Driven Mechanical Representation Of A Biological System, Andrea Argouarch, Michael Mceachern, Brandon Parham
Biomedical Engineering
No abstract provided.