Biomedical Engineering and Bioengineering Commons^™

Differential Gene Expression To Investigate The Effects Of Low-Level Electrochemical Currents On Bacillus Subtilis., Robert Szkotak, Tagbo H R Niepa, Nikhil Jawrani, Jeremy L. Gilbert, Marcus B. Jones, Dacheng Ren

Biomedical and Chemical Engineering - All Scholarship

With the emergence and spread of multidrug resistant bacteria, effective methods to eliminate both planktonic bacteria and those embedded in surface-attached biofilms are needed. Electric currents at uA-mA/cm2 range are known to reduce the viability of bacteria. However, the mechanism of such effects is still not well understood. In this study, Bacillus subtilis was used as the model Gram-positive species to systematically investigate the effects of electrochemical currents on bacteria including the morphology, viability, and gene expression of planktonic cells, and viability of biofilm cells. The data suggest that weak electrochemical currents can effectively eliminate B. subtilis both as planktonic …

Structure And Optical Properties Of Self-Assembled Multicomponent Plasmonic Nanogels, Tao Cong, Satvik N. Wani, Peter Anthony Paynter, Radhakrishna Sureshkumar

Biomedical and Chemical Engineering - All Scholarship

Multicomponent plasmonic nanogels (PNGs) capable of broadband absorption of light in the 400-700 nm wavelength range were synthesized by the self-assembly of metal nanoparticles with wormlike surfactant micelles. Small angle x-ray scattering and rheological experiments suggest that the nanoparticles bridge micelle fragments to aid the formation a stable gel phase with exceptional color uniformity. Their optical absorbance could be robustly tuned by changing the nanoparticle type (Au/Ag), size, shape, and/or concentration. The PNGs have relatively low viscosity and are thermoreversible. Potential applications to the manufacturing of coatings and interfaces for solar energy harvesting and reconfigurable optical devices can be envisioned.

The Effect Of Maternal Diet On Fetal Development, Catherine Wilcox

Honors Capstone Projects - All

Using mice as a model system, this study aimed to compare the effect of a high fat diet (HFD), high sugar diet (HSD) and a control diet (CD) on fetal growth and development at the time of birth (post-natal day 0 or PND 0), post-natal day 7 (PND 7) and post-natal day 14 (PND 14). Published literature has documented the effects of a negative in-utero environment on fetal development, but currently there is limited research regarding the continued effects on development after birth. Mouse pups were harvested and then imaged in 3-D using a high-resolution micro-computed tomography (micro-CT) system. Total …

Electrochemical Investigation Of Chromium Nanocarbide Coated Ti-6al-4v And Co-Cr-Mo Alloy Substrates, Viswanathan Swaminathan, Haitong Zeng, Daniel Lawrynowicz, Zongtao Zhang, Jeremy L. Gilbert

Biomedical and Chemical Engineering - All Scholarship

This study investigated the electrochemical behavior of chromium nano-carbide cermet coating applied on Ti–6Al–4V and Co–Cr–Mo alloys for potential application as wear and corrosion resistant bearing surfaces. The cermet coating consisted of a highly heterogeneous combination of carbides embedded in a metal matrix. The main factors studied were the effect of substrate (Ti–6Al–4V vs. Co–Cr–Mo), solution conditions (physiological vs. 1 M H₂O₂ of pH 2), time of immersion (1 vs. 24 h) and post coating treatments (passivation and gamma sterilization). The coatings were produced with high velocity oxygen fuel (HVOF) thermal spray technique at atmospheric conditions to …

Issues On Clean Diesel Combustion Technology Using Supercritical Fluids: Thermophysical Properties And Thermal Stability Of Diesel Fuel, Ronghong Lin

Biomedical and Chemical Engineering - Dissertations

The clean diesel combustion technology using supercritical fluids is aimed to both improve fuel economy and reduce harmful emissions. This novel process involves preparation, injection and combustion of supercritical fuel/diluents mixtures. Design and development of this new process require a deep understanding of fuel properties. The current study has attempted to address three fuel property related issues: fuel surrogates, diffusivity and thermal stability.

Fuel surrogates are often used in engine research to mimic real fuel properties. In this work, ten diesel fuel surrogates were investigated, and the ability of these surrogates to predict diesel fuel properties was evaluated. It was …