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Biomedical Engineering and Bioengineering Commons

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Full-Text Articles in Biomedical Engineering and Bioengineering

Simulations Of Transient Membrane Behavior In Cells Subjected To A High-Intensity Ultrashort Electric Pulse, Q. Hu, S. Viswanadham, R. P. Joshi, Karl H. Schoenbach, Stephen J. Beebe, P. F. Blackmore May 2005

Simulations Of Transient Membrane Behavior In Cells Subjected To A High-Intensity Ultrashort Electric Pulse, Q. Hu, S. Viswanadham, R. P. Joshi, Karl H. Schoenbach, Stephen J. Beebe, P. F. Blackmore

Bioelectrics Publications

A molecular dynamics (MD) scheme is combined with a distributed circuit model for a self-consistent analysis of the transient membrane response for cells subjected to an ultrashort (nanosecond) high-intensity (approximately 0.01-V/nm spatially averaged field) voltage pulse. The dynamical, stochastic, many-body aspects are treated at the molecular level by resorting to a course-grained representation of the membrane lipid molecules. Coupling the Smoluchowski equation to the distributed electrical model for current flow provides the time-dependent transmembrane fields for the MD simulations. A good match between the simulation results and available experimental data is obtained. Predictions include pore formation times of about 5-6 …


Room-Temperature Atmospheric Pressure Plasma For Biomedical Applications, Mounir Laroussi, Xinpei Lu Jan 2005

Room-Temperature Atmospheric Pressure Plasma For Biomedical Applications, Mounir Laroussi, Xinpei Lu

Electrical & Computer Engineering Faculty Publications

As low-temperature non-equilibrium plasmas come to play an increasing role in biomedical applications, reliable and user-friendly sources need to be developed. These plasma sources have to meet stringent requirements such as low temperature (at or near room temperature), no risk of arcing, operation at atmospheric pressure, preferably hand-held operation, low concentration of ozone generation, etc. In this letter, we present a device that meets exactly such requirements. This device is capable of generating a cold plasma plume several centimeters in length. It exhibits low power requirements as shown by its current-voltage characteristics. Using helium as a carrier gas, very little …


Bioengineering Instructional Framework For Technology Education, Philip A. Reed, Technology Education Department, Old Dominion University, Virginia Bioengineering Writing Team Jan 2005

Bioengineering Instructional Framework For Technology Education, Philip A. Reed, Technology Education Department, Old Dominion University, Virginia Bioengineering Writing Team

STEMPS Faculty Publications

No abstract provided.