Biomedical Engineering and Bioengineering Commons^™

Characterization Of Engineered Human Lung Tissue, Benjamin Boytor

FIU Electronic Theses and Dissertations

Characterizing engineered human lung tissue is an important step in developing a functional tissue replacement for lung tissue repair and in vitro analysis. Small tissue constructs were grown by seeding IMR-90 fetal lung fibroblasts and adult microvascular endothelial cells onto a Polyglycolic acid (PGA) polymer template. Introducing the constructs to dynamic culture conditions inside a bioreactor facilitated three-dimensional growth seen in scanning electron microscopy images (SEM).

Characterization of the resultant tissue samples was done using SEM imagery, tensile tests, and biochemical assays to quantify extra-cellular matrix (ECM) composition. Tensile tests of the engineered samples indicated an increase in the mechanical …

Bme Stats Fall 2002, Department Of Biomedical Engineering, Florida International University

STATS

No abstract provided.

Bme Stats Spring 2002, Department Of Biomedical Engineering, Florida International University

STATS

No abstract provided.