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Z-Protected Glutamic Acid-Based Biodegradable Thermoplastic And Thermosetting Polyesters: Synthesis And Characterization, R M. Tadros, Hossein Noureddini, Delmar C. Timm

Papers in Biomaterials

Biodegradable polymers were formed from N-benzyloxycarbonyl-L-glutamic acid with the comono-mers ethylene glycol, diglycidyl ether of 1,4-butanediol, and diglycidyl ether of bisphenol A. The three polymers were a linear and a rosslinked heterochain polyester and a crosslinked polyester that contained aromatic units within its network chains. The thermoplastic resin and the soluble fractions for the thermo-setting resins were characterized by gel permeation chromatography. Conversions for carboxylic acid were determined by titrations. A quality, 22,000 molecular weight thermoplastic resin was formed. The two ther-mosets were cured past their gel points. Gelation analysis revealed that the relative rate constants for the sequential oxirane/ …